Research of vertical sections of rats' tubular bones in simulation of reduction bone tissue mineral density using Raman spectrum method

2017 ◽  
Author(s):  
Elena V. Timchenko ◽  
Pavel E. Timchenko ◽  
Dmitry A. Dolgyshkin ◽  
Larisa T. Volova ◽  
Anna A. Asadova ◽  
...  
Keyword(s):  
Raman Spectrum ◽  
Bone Tissue ◽  
Mineral Density ◽  
Spectrum Method ◽  
Tissue Mineral Density ◽  
Vertical Sections ◽  
Tubular Bones

Features of the structural and functional state of bone tissue in patients with generalized periodontitis who live in different anthropogenically loaded areas

2020 ◽  
Vol 33 (2) ◽  
Author(s):  
Khrystyna Kovalyshyn ◽  
Mykola Rozhko
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Metabolism ◽  
Bone Tissue ◽  
Functional State ◽  
Mineral Density ◽  
Tissue Mineral Density ◽  
Degree Of Severity

Introduction. A research was conducted of the features of the structural and functional state of bone tissue in patients with generalized periodontitis with rheumatoid arthritis who live in different anthropogenically loaded areas. Aim. The aim of the research is to assess the bone tissue mineral density according to the indicators of densitometric researches and the level of a marker of bone metabolism in generalized periodontitis of I and II degree of severity. Material and methods. We examined 105 patients with GP of the I and II degree of severity, among whom were patients with rheumatoid arthritis who live in environmentally favorable and unfavorable areas. Peculiarities of the structural and functional state of bone tissue were assessed using an ultrasonic densitometer Sunlight Mini Omni TM and the level of a marker of bone tissue resorption of deoxypyridinoline in urine. Results. Patients with generalized periodontitis with rheumatoid arthritis who live in environmentally unfavorable areas, found the largest number of people with signs of osteopenia, osteoporosis and elevated levels of deoxypyridinoline. In particular, in generalized periodontitis of the II degree of severity with osteopenia – 14 people (48.27%), with osteoporosis – 9 people (31%), the level of deoxypyridinoline determined in women was 12.03 ± 0.16 n/mol, which in 2.2 times significantly higher than the group of healthy (p < 0.001). Conclusions. According to densitometric parameters and the level of deoxypyridinoline in the urine, the acceleration of bone tissue resorption in patients with generalized periodontitis of the II degree of severity with rheumatoid arthritis who live in environmentally unfavorable areas was established.

scholarly journals Hormones and osteoporosis

1994 ◽  
Vol 40 (3) ◽  
pp. 49-52
Author(s):  
O. K. Shiraliyev ◽  
T. F. Mamedov ◽  
Zh. I. Gaghiyeva
Keyword(s):  
Trabecular Bone ◽  
Bone Tissue ◽  
Bone Fractures ◽  
The Body ◽  
High Porosity ◽  
Vital Activity ◽  
Mineral Density ◽  
Simultaneous Formation ◽  
Trabecular Bones ◽  
Tubular Bones

Osteoporosis and its complications - bone fractures - represent a significant medical and social problem. Due to osteoporosis, bone fractures occur annually in 1.3 million Americans and 40 thousand Canadians. In France, one in two, and in Australia, one in five women aged about 70 years, suffer from fractures caused by osteoporosis. The occurrence of osteoporosis in old women is due to a decrease in estrogen production. However, a decrease in bone mineral density occurs not only with age, but even more so with all conditions leading to a change in the balance of hormones of the hypothalamic-pituitary system, thyroid and parathyroid glands, and adrenal glands. In connection with the stated purpose of this work was a synthesis of literature data on the effect of hormones on the occurrence and development of osteoporosis. Bone tissue is a dynamic metabolically active system. Depending on the function performed, cortical and trabecular bone are distinguished. The first makes up three quarters of the entire skeletal mass, forms the diaphysis of the tubular bones, has a low porosity, performs the function of supporting soft tissues and transmitting muscle contraction from one part of the body to another. Trabecular bone tissue makes up one fourth of the mass of the skeleton, forms the bones of the axial skeleton and the epiphysis of the tubular bones, has high porosity and ensures normal vital activity of the bone marrow. To do this, in the trabecular bones there are cavities ranging in size from 500 to 1000 microns, located between bone plates 100-150 microns thick. The basis of the vital activity of bone tissue is the functioning of two types of cells: osteoclasts resorbing the bone, and osteoblasts responsible for its formation. The ancestors of these cells are not fully understood, although hematopoietic monocyte macrophages are considered the most probable for osteoclasts, and stromal cells for osteoblasts, from which preosteoblasts arise. Throughout life, there is a constant renewal of bones, manifested in the resorption of individual, very small sections of tissue, with the almost simultaneous formation of a new bone. This process is of great evolutionary importance, since it allows you to remove microtrauma and bone microcracks that arise during the life process. Annually 25% of the mass of the trabecular bones and only 2-3% of the cortical bones are renewed.

scholarly journals Increased variability of bone tissue mineral density resulting from estrogen deficiency influences creep behavior in a rat vertebral body

Bone ◽  
2012 ◽  
Vol 51 (5) ◽  
pp. 868-875 ◽  
Author(s):  
Do-Gyoon Kim ◽  
Anand R. Navalgund ◽  
Boon Ching Tee ◽  
Garrett J. Noble ◽  
Richard T. Hart ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Vertebral Body ◽  
Creep Behavior ◽  
Estrogen Deficiency ◽  
Mineral Density ◽  
Tissue Mineral Density

Comparative evaluation of the peri-implant bone tissue mineral density around unloaded titanium dental implants

2007 ◽  
Vol 35 (1) ◽  
pp. 84-92 ◽  
Author(s):  
Tonino Traini ◽  
Marco Degidi ◽  
Giovanna Iezzi ◽  
Luciano Artese ◽  
Adriano Piattelli
Keyword(s):  
Bone Tissue ◽  
Dental Implants ◽  
Comparative Evaluation ◽  
Mineral Density ◽  
Tissue Mineral Density ◽  
Titanium Dental Implants

scholarly journals Heidelberg-mCT-Analyzer: a novel method for standardized microcomputed-tomography-guided evaluation of scaffold properties in bone and tissue research

2015 ◽  
Vol 2 (11) ◽  
pp. 150496 ◽  
Author(s):  
Fabian Westhauser ◽  
Christian Weis ◽  
Melanie Hoellig ◽  
Tyler Swing ◽  
Gerhard Schmidmaier ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Three Dimensional ◽  
Characteristic Parameter ◽  
Micro Computed Tomography ◽  
Mineral Density ◽  
Independent Analysis ◽  
Scaffold Properties

Bone tissue engineering and bone scaffold development represent two challenging fields in orthopaedic research. Micro-computed tomography (mCT) allows non-invasive measurement of these scaffolds’ properties in vivo . However, the lack of standardized mCT analysis protocols and, therefore, the protocols’ user-dependency make interpretation of the reported results difficult. To overcome these issues in scaffold research, we introduce the Heidelberg-mCT-Analyzer. For evaluation of our technique, we built 10 bone-inducing scaffolds, which underwent mCT acquisition before ectopic implantation (T0) in mice, and at explantation eight weeks thereafter (T1). The scaffolds’ three-dimensional reconstructions were automatically segmented using fuzzy clustering with fully automatic level-setting. The scaffold itself and its pores were then evaluated for T0 and T1. Analysing the scaffolds’ characteristic parameter set with our quantification method showed bone formation over time. We were able to demonstrate that our algorithm obtained the same results for basic scaffold parameters (e.g. scaffold volume, pore number and pore volume) as other established analysis methods. Furthermore, our algorithm was able to analyse more complex parameters, such as pore size range, tissue mineral density and scaffold surface. Our imaging and post-processing strategy enables standardized and user-independent analysis of scaffold properties, and therefore is able to improve the quantitative evaluations of scaffold-associated bone tissue-engineering projects.

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