scholarly journals Increased variability of bone tissue mineral density resulting from estrogen deficiency influences creep behavior in a rat vertebral body

Bone ◽  
2012 ◽  
Vol 51 (5) ◽  
pp. 868-875 ◽  
Author(s):  
Do-Gyoon Kim ◽  
Anand R. Navalgund ◽  
Boon Ching Tee ◽  
Garrett J. Noble ◽  
Richard T. Hart ◽  
...  
2009 ◽  
Vol 11 (1) ◽  
pp. 23-27 ◽  
Author(s):  
Thomas R. Blattert ◽  
Stefan Glasmacher ◽  
Hans-Joachim Riesner ◽  
Christoph Josten

In generalized osteoporosis, instrumentation with cement-augmented pedicle screws is an amplification of the therapeutic spectrum. Early clinical results are promising for both solid and cannulated screws; however, there are concerns regarding the revision characteristics of these screws, especially for the cannulated-fenestrated type with its continuous cement interconnection from the core of the screw to surrounding bone tissue. In a human cadaver model, bone mineral density (BMD) was assessed radiographically. Spinal levels T9–L4 were instrumented left unilaterally, transpedicularly by using cannulated-fenestrated pedicle screws with the dimensions 6.5 × 45 mm. Polymethylmethacrylate cement (1.5 ml) was injected through the screws into each vertebra. After polymerization of the cement, the extraction torque was recorded. For both implantation and explantation of the screws, a fluoroscope was used to guarantee correct screw and cement positioning and to observe possible co-movements—that is, any movement of the cement mass within the vertebral body upon removal of the screw. For comparison, the extraction torque of same-dimension pedicle screws was recorded in a nonosteoporotic, non–cement-augmented instrumentation. The BMD was 0.60 g/cm2, a level that corresponds to a severe grade of osteoporosis. For removal of the screws, the median and mean extraction torques were 34 and 49 ± 44 Ncm, respectively. No co-movements of the cement mass occurred within the vertebral body. In the nonosteoporotic control, BMD was 1.38 g/cm2. The median and mean extraction torques were 123 and 124 ± 12 Ncm, respectively. Thus, the revision characteristics of cement-augmented, cannulated-fenestrated pedicle screws are not problematic, even in cases of severe osteoporosis. The winglike cement interconnection between the screw core and surrounding bone tissue is fragile enough to break off in the event of an extraction torque and to release the screw. There is no proof to support the theoretical fear that while trying to remove a screw, the composite of screw and cement would not break but instead would rotate as a whole in the osteoporotic vertebral body.


2016 ◽  
Vol 23 (4) ◽  
pp. 44-49
Author(s):  
N. V Bogomolova ◽  
A. E Shul’ga ◽  
V. V Zaretskov ◽  
A. A Smol’kin ◽  
I. A Norkin

The analysis of the results of morphologic examination of vertebral body bone tissue obtained intraoperatively from 43 patients (20 - 67 years) with thoracic and lumbar spine injuries at different terms after trauma was performed. All patients were operated on via anterior approach to create ventral fusion. In the examined serial samples of vertebral body structures the quality and regeneration potential of bone tissue were assessed. It was shown that cell differentiation during the osteogenesis process was closely associated with angiogenesis. In the zones with active growth of microcirculatory bed vessels the normal cycle of osteoblast and osteocytes took place while hypoxia and acidosis resulted in pathologic osteogenesis. In patients under 50 years, both males and females) the full value consolidation time averaged 5 months. In patients over 50 years, independently of the gender, the decrease of spongy structures volume and bone mineral density was observed. The recommendations on surgical treatment tactics of patients with thoracic and lumbar vertebral body injuries were given.


2010 ◽  
Vol 55 (8) ◽  
pp. 599-605 ◽  
Author(s):  
Matthew S. Ames ◽  
Semi Hong ◽  
Hye Ri Lee ◽  
Henry W. Fields ◽  
William M. Johnston ◽  
...  

2020 ◽  
Vol 33 (2) ◽  
Author(s):  
Khrystyna Kovalyshyn ◽  
Mykola Rozhko

Introduction. A research was conducted of the features of the structural and functional state of bone tissue in patients with generalized periodontitis with rheumatoid arthritis who live in different anthropogenically loaded areas. Aim. The aim of the research is to assess the bone tissue mineral density according to the indicators of densitometric researches and the level of a marker of bone metabolism in generalized periodontitis of I and II degree of severity. Material and methods. We examined 105 patients with GP of the I and II degree of severity, among whom were patients with rheumatoid arthritis who live in environmentally favorable and unfavorable areas. Peculiarities of the structural and functional state of bone tissue were assessed using an ultrasonic densitometer Sunlight Mini Omni TM and the level of a marker of bone tissue resorption of deoxypyridinoline in urine. Results. Patients with generalized periodontitis with rheumatoid arthritis who live in environmentally unfavorable areas, found the largest number of people with signs of osteopenia, osteoporosis and elevated levels of deoxypyridinoline. In particular, in generalized periodontitis of the II degree of severity with osteopenia – 14 people (48.27%), with osteoporosis – 9 people (31%), the level of deoxypyridinoline determined in women was 12.03 ± 0.16 n/mol, which in 2.2 times significantly higher than the group of healthy (p < 0.001). Conclusions. According to densitometric parameters and the level of deoxypyridinoline in the urine, the acceleration of bone tissue resorption in patients with generalized periodontitis of the II degree of severity with rheumatoid arthritis who live in environmentally unfavorable areas was established.


2011 ◽  
Vol 0 (4) ◽  
pp. 100
Author(s):  
Volodymyr Radchenko ◽  
Sergey Kosterin ◽  
Ninel Diedukh ◽  
Natalya Ashukina

Sign in / Sign up

Export Citation Format

Share Document