Automatic estimation of retinal nerve fiber bundle orientation in SD-OCT images using a structure-oriented smoothing filter

2017 ◽  
Author(s):  
Babak Ghafaryasl ◽  
Robert Baart ◽  
Johannes F. de Boer ◽  
Koenraad A. Vermeer ◽  
Lucas J. van Vliet
Keyword(s):  
Nerve Fiber ◽  
Fiber Bundle ◽  
Smoothing Filter ◽  
Automatic Estimation ◽  
Sd Oct ◽  
Retinal Nerve Fiber

scholarly journals Detection of Retinal Nerve Fiber Layer Defects in Alzheimer’s Disease Using SD-OCT

2014 ◽  
Vol 5 ◽  
Author(s):  
Robert Kromer ◽  
Nermin Serbecic ◽  
Lucrezia Hausner ◽  
Lutz Froelich ◽  
Fahmy Aboul-Enein ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Sd Oct ◽  
Retinal Nerve Fiber

scholarly journals Age-Related Physiologic Thinning Rate of the Retinal Nerve Fiber Layer in Different Levels of Myopia

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Daun Jeong ◽  
Kyung Rim Sung ◽  
Youn Hye Jo ◽  
Sung-cheol Yun
Keyword(s):  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Refractive Error ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Rnfl Thickness ◽  
Significant Difference ◽  
Thinning Rate ◽  
Sd Oct ◽  
Retinal Nerve Fiber

Purpose. To investigate the effect of refractive error on the physiologic thinning rate of the retinal nerve fiber layer (RNFL) in healthy eyes. Materials and Methods. This study analyzed 223 eyes of 141 healthy subjects followed for more than 5 years and underwent at least five serial spectral domain optical coherence tomography (SD-OCT) examinations. Longitudinal RNFL measurements were analyzed by linear mixed models incorporating follow-up duration, baseline RNFL thickness, spherical equivalent (SE), age, intraocular pressure, and visual field mean deviation. Thinning rates were classified according to SE into three groups: nonmyopic (NM; >0 D), mild-to-moderately myopic (MM; >–6 D and ≤0 D), and highly myopic (HM; ≤–6 D). Results. The overall slopes of change in RNFL thickness over time in the NM, MM, and HM groups were −0.305 ± 0.128, −0.294 ± 0.068, and −0.208 ± 0.097 μm/yr, respectively. Slopes of RNFL thickness changes in these groups were −0.514 ± 0.248, −0.520 ± 0.133, and −0.528 ± 0.188 μm/yr, in the superior quadrant; −0.084 ± 0.145, 0.107 ± 0.082, and −0.161 ± 0.112 μm/yr, in the temporal quadrant; −0.807 ± 0.242, −0.794 ± 0.130, and −0.727 ± 0.183 μm/yr, in the inferior quadrant; and 0.160 ± 0.157, 0.118 ± 0.084, and 0.429 ± 0.119 μm/yr, in the nasal quadrant. Overall and in all four quadrants, there was no significant difference in the rate of RNFL thickness change among the three groups. Conclusions. Refractive error did not affect the physiologic thinning rate of RNFL when assessed by SD OCT.

The Ability of Macular Parameters and Circumpapillary Retinal Nerve Fiber Layer by Three SD-OCT Instruments to Diagnose Highly Myopic Glaucoma

2013 ◽  
Vol 54 (9) ◽  
pp. 6025 ◽  
Author(s):  
Azusa Akashi ◽  
Akiyasu Kanamori ◽  
Makoto Nakamura ◽  
Masashi Fujihara ◽  
Yuko Yamada ◽  
...  
Keyword(s):  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Sd Oct ◽  
Retinal Nerve Fiber

scholarly journals Novel Technique for Quantifying Retinal Nerve Fiber Bundle Abnormality in the Temporal Raphe

2018 ◽  
Vol 95 (4) ◽  
pp. 309-317 ◽  
Author(s):  
Bright S. Ashimatey ◽  
Brett J. King ◽  
Victor E. Malinovsky ◽  
William H. Swanson
Keyword(s):  
Nerve Fiber ◽  
Fiber Bundle ◽  
Novel Technique ◽  
Retinal Nerve Fiber

Retinal vessel course and retinal nerve fiber bundle trajectories in the human eye

2014 ◽  
Vol 92 ◽  
pp. 0-0
Author(s):  
NM JANSONIUS ◽  
K QIU ◽  
J SCHIEFER ◽  
J NEVALAINEN ◽  
J PAETZOLD ◽  
...  
Keyword(s):  
Nerve Fiber ◽  
Fiber Bundle ◽  
Retinal Vessel ◽  
Human Eye ◽  
Retinal Nerve Fiber

Pilot Study of Eyesight Characteristics and Thickness of the Retinal Nerve Fiber and Ganglion Cell-inner Plexiform Layers in Adolescent Patients with Type one Diabetes Mellitus on an Insulin Pump

2018 ◽  
Vol 24 (27) ◽  
pp. 3264-3275
Author(s):  
Dorota Raczyńska ◽  
Beata Bzoma ◽  
Katarzyna Sielachowicz ◽  
Agnieszka Brandt ◽  
Dorota Chomińska-Dorn ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Nerve Fiber ◽  
Insulin Pump ◽  
Vascular Complications ◽  
Glycated Haemoglobin ◽  
Diabetic Patients ◽  
Plexiform Layers ◽  
Sd Oct ◽  
Retinal Nerve Fiber

Aim: Estimation of the ocular status in adolescents with diabetes mellitus type 1 (DM1) treated with continuous subcutaneous insulin infusion (CSII), assessment of the development of the diabetic retinopathy (DR) and nephropathy (DN) within 10 years. Methods: 37 patients (74 eyes) aged 16-33 years, treated with CSII were enrolled to the study. Baseline, and a 10- year follow-up evaluation included: best corrected visual acuity (BCVA), tonometry, slit lamp exam and fluorescein angiography (FLA). Additionally, spectral-domain optical coherence tomography (SD-OCT) was done in the 7th year of observation to assess the thickness of the retinal nerve fiber (RNFL) and the ganglion cellinner plexiform layers (GCL-IPL) complex thickness. Glycated haemoglobin (HbA1) and albuminuria were also analysed. Results: During the 10-year observation period DR (non-proliferative - NPDR, proliferative - PDR, diabetic macular edema - DME) was diagnosed in 3 (8%) patients. In the DR group: BCVA was significantly lower, intraocular pressure (IOP) levels and albuminuria were higher. There were no differences in HbA1 in both groups. The thinning of RNFL was observed in both groups. Macular RNFL, GCL-IPL complex thickness assessment showed a significantly higher number of borderline results in the group with DR. Conclusions: Diabetic patients treated with CSII are at a lower risk of developing vascular complications even with poor metabolic control. Increased albuminuria may be a predictive sign for early ocular complications, and requires intense observation. Diagnosis of RNFL and GCL-IPL decreased values is crucial prior to diabetic retinopathy development. SD-OCT is a non-invasive, easy-to-perform, relatively inexpensive procedure, and can be a useful tool to monitor neuropathy progression.

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