The Ability of Macular Parameters and Circumpapillary Retinal Nerve Fiber Layer by Three SD-OCT Instruments to Diagnose Highly Myopic Glaucoma

2013 ◽  
Vol 54 (9) ◽  
pp. 6025 ◽  
Author(s):  
Azusa Akashi ◽  
Akiyasu Kanamori ◽  
Makoto Nakamura ◽  
Masashi Fujihara ◽  
Yuko Yamada ◽  
...  
Keyword(s):  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Sd Oct ◽  
Retinal Nerve Fiber

scholarly journals Detection of Retinal Nerve Fiber Layer Defects in Alzheimer’s Disease Using SD-OCT

2014 ◽  
Vol 5 ◽  
Author(s):  
Robert Kromer ◽  
Nermin Serbecic ◽  
Lucrezia Hausner ◽  
Lutz Froelich ◽  
Fahmy Aboul-Enein ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Sd Oct ◽  
Retinal Nerve Fiber

scholarly journals Age-Related Physiologic Thinning Rate of the Retinal Nerve Fiber Layer in Different Levels of Myopia

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Daun Jeong ◽  
Kyung Rim Sung ◽  
Youn Hye Jo ◽  
Sung-cheol Yun
Keyword(s):  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Refractive Error ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Rnfl Thickness ◽  
Significant Difference ◽  
Thinning Rate ◽  
Sd Oct ◽  
Retinal Nerve Fiber

Purpose. To investigate the effect of refractive error on the physiologic thinning rate of the retinal nerve fiber layer (RNFL) in healthy eyes. Materials and Methods. This study analyzed 223 eyes of 141 healthy subjects followed for more than 5 years and underwent at least five serial spectral domain optical coherence tomography (SD-OCT) examinations. Longitudinal RNFL measurements were analyzed by linear mixed models incorporating follow-up duration, baseline RNFL thickness, spherical equivalent (SE), age, intraocular pressure, and visual field mean deviation. Thinning rates were classified according to SE into three groups: nonmyopic (NM; >0 D), mild-to-moderately myopic (MM; >–6 D and ≤0 D), and highly myopic (HM; ≤–6 D). Results. The overall slopes of change in RNFL thickness over time in the NM, MM, and HM groups were −0.305 ± 0.128, −0.294 ± 0.068, and −0.208 ± 0.097 μm/yr, respectively. Slopes of RNFL thickness changes in these groups were −0.514 ± 0.248, −0.520 ± 0.133, and −0.528 ± 0.188 μm/yr, in the superior quadrant; −0.084 ± 0.145, 0.107 ± 0.082, and −0.161 ± 0.112 μm/yr, in the temporal quadrant; −0.807 ± 0.242, −0.794 ± 0.130, and −0.727 ± 0.183 μm/yr, in the inferior quadrant; and 0.160 ± 0.157, 0.118 ± 0.084, and 0.429 ± 0.119 μm/yr, in the nasal quadrant. Overall and in all four quadrants, there was no significant difference in the rate of RNFL thickness change among the three groups. Conclusions. Refractive error did not affect the physiologic thinning rate of RNFL when assessed by SD OCT.

Comparative data on SD-OCT for the retinal nerve fiber layer and retinal macular thickness in a large cohort with Marfan syndrome

2017 ◽  
Vol 38 (1) ◽  
pp. 34-38 ◽  
Author(s):  
WanWan Xu ◽  
Sudhi P. Kurup ◽  
Amani A. Fawzi ◽  
Mary K. Durbin ◽  
Irene H. Maumenee ◽  
...  
Keyword(s):  
Nerve Fiber ◽  
Marfan Syndrome ◽  
Retinal Nerve Fiber Layer ◽  
Large Cohort ◽  
Macular Thickness ◽  
Comparative Data ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Sd Oct ◽  
Retinal Nerve Fiber

Effects of Axial Length and Age on Circumpapillary Retinal Nerve Fiber Layer and Inner Macular Parameters Measured by 3 Types of SD-OCT Instruments

2016 ◽  
Vol 25 (4) ◽  
pp. 383-389 ◽  
Author(s):  
Kaori Ueda ◽  
Akiyasu Kanamori ◽  
Azusa Akashi ◽  
Mari Tomioka ◽  
Yuki Kawaka ◽  
...  
Keyword(s):  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Axial Length ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Sd Oct ◽  
Retinal Nerve Fiber

scholarly journals Evaluation of retinal nerve fiber layer thickness in patients of pituitary adenomas with and without optic chiasmal compression

2019 ◽  
Author(s):  
Kun Lei ◽  
Lina Wang ◽  
Meizi Wang ◽  
Shuran Wang ◽  
Yuanzhen Qu
Keyword(s):  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Pituitary Tumors ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Chiasmal Compression ◽  
Nerve Fiber Layer Thickness ◽  
Significant Difference ◽  
Sd Oct ◽  
Retinal Nerve Fiber

Abstract Background: Numerous studies have demonstrated loss of circumpapillary retinal nerve fiber layer (cpRNFL) thickness in patients with chiasmal compression using optical coherence tomography (OCT). This study aimed to evaluate the cpRNFL and ganglion cell compound (GCC) thicknesses in patients suffering pituitary tumors with and without chiasmal compression. Methods: forty-four patients with pituitary adenoma (PA) (twenty-one without chiasmal compression and twenty-three with chiasmal compression) and eighteen controls were enrolled. cpRNFL and GCC thickness were measured in both patients and controls by SD-OCT. Results: three groups (PAs with optic chiasmal compression, PAs without optic chiasmal compression and controls) were closely matched in terms of mean age, sex and IOP (p=0.173, p=0.184 and P=0.343, respectively). The average cpRNFL and GCC thickness was significantly different among three groups (cpRNFL : 94.1±12.5µm, 106.4±7.3µm, 110.7±6.9µm, respectively; GCC: 85.8±6.9µm, 93.8±5.0µm, 97.2±5.6µm, respectively ). The cpRNFL was analyzed in different regions, and significant difference was found in nasal upper and nasal lower between PAs without optic chiasmal compression and controls. Conclusion: Even there is no evidence of compression at the chiasm on magnetic resonance imaging (MRI), GCC and cpRNFL thinning could still be detected in patients of pituitary tumor by SD-OCT. The loss of RNFL is more severe in patients with chiasmal compression.

scholarly journals Effects of Misalignments in the Retinal Nerve Fiber Layer Thickness Measurements with Spectral Domain Optical Coherence Tomography

2014 ◽  
Vol 2014 ◽  
pp. 1-7
Author(s):  
Kleyton A. Barella ◽  
Fernanda Cremasco ◽  
Camila Zangalli ◽  
Vital P. Costa
Keyword(s):  
Nerve Fiber ◽  
Layer Thickness ◽  
Retinal Nerve Fiber Layer ◽  
Fiber Layer ◽  
Cross Sectional ◽  
Nerve Fiber Layer ◽  
Nerve Fiber Layer Thickness ◽  
Significant Difference ◽  
Sd Oct ◽  
Retinal Nerve Fiber

Purpose. To investigate misalignments (MAs) on retinal nerve fiber layer thickness (RNFLT) measurements obtained withCirrus©SD-OCT.Methods. This was a retrospective, observational, cross-sectional study. Twenty-seven healthy and 29 glaucomatous eyes of 56 individuals with one normal exam and another showing MA were included. MAs were defined as an improper alignment of vertical vessels in the en face image. MAs were classified in complete MA (CMA) and partial MA (PMA), according to their site: 1 (superior, outside the measurement ring (MR)), 2 (superior, within MR), 3 (inferior, within MR), and 4 (inferior, outside MR). We compared RNFLT measurements of aligned versus misaligned exams in all 4 sectors, in the superior area (sectors 1 + 2), inferior area (sectors 3 + 4), and within the measurement ring (sectors 2 + 3).Results. RNFLT measurements at 12 clock-hour of eyes with MAs in the superior area (sectors 1 + 2) were significantly lower than those obtained in the same eyes without MAsP=0.043. No significant difference was found in other areas (sectors 1 + 2 + 3 + 4, sectors 3 + 4, and sectors 2 + 3).Conclusion. SD-OCT scans with superior MAs may present lower superior RNFLT measurements compared to aligned exams.

The Optimal Diameter for Circumpapillary Retinal Nerve Fiber Layer Thickness Measurement by SD-OCT in Glaucoma

2018 ◽  
Vol 27 (12) ◽  
pp. 1086-1093
Author(s):  
Ludwig M. Heindl ◽  
Werner Adler ◽  
Ouahiba El-Malahi ◽  
Friederike Schaub ◽  
Manuel M. Hermann ◽  
...  
Keyword(s):  
Nerve Fiber ◽  
Layer Thickness ◽  
Retinal Nerve Fiber Layer ◽  
Thickness Measurement ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Nerve Fiber Layer Thickness ◽  
Optimal Diameter ◽  
Sd Oct ◽  
Retinal Nerve Fiber
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