In vivo imaging of gold nanorod contrast agents using photothermal optical coherence tomography

2013 ◽  
Author(s):  
Jason M. Tucker-Schwartz ◽  
Travis A. Meyer ◽  
Chetan A. Patil ◽  
Craig L. Duvall ◽  
Melissa C. Skala
Keyword(s):  
Optical Coherence Tomography ◽  
Contrast Agents ◽  
In Vivo Imaging ◽  
Gold Nanorod ◽  
Optical Coherence

scholarly journals A Spectral Demixing Model for Triplex In Vivo Imaging of Optical Coherence Tomography Contrast Agents

ACS Photonics ◽  
2020 ◽  
Vol 7 (4) ◽  
pp. 893-900
Author(s):  
Edwin Yuan ◽  
Peng Si ◽  
Yonatan Winetraub ◽  
Saba Shevidi ◽  
Adam de la Zerda
Keyword(s):  
Optical Coherence Tomography ◽  
Contrast Agents ◽  
In Vivo Imaging ◽  
Optical Coherence

scholarly journals In vivo photothermal optical coherence tomography of gold nanorod contrast agents

2012 ◽  
Vol 3 (11) ◽  
pp. 2881 ◽  
Author(s):  
J. M. Tucker-Schwartz ◽  
T. A. Meyer ◽  
C. A. Patil ◽  
C. L. Duvall ◽  
M. C. Skala
Keyword(s):  
Optical Coherence Tomography ◽  
Contrast Agents ◽  
Gold Nanorod ◽  
Optical Coherence

scholarly journals A Spectral De-mixing Model for Triplex In Vivo Imaging of Optical Coherence Tomography Contrast Agents

2019 ◽  
Author(s):  
Edwin Yuan ◽  
Peng Si ◽  
Saba Shevidi ◽  
Adam de la Zerda
Keyword(s):  
Optical Coherence Tomography ◽  
Contrast Agent ◽  
Contrast Agents ◽  
In Vivo Imaging ◽  
Spectroscopic Technique ◽  
Optical Coherence ◽  
Single Voxel ◽  
Gold Nanobipyramids

The ability to detect multiple contrast agents simultaneously would greatly enhance Optical Coherence Tomography (OCT) images, providing nuanced biological context to physiological structures. However, previous OCT contrast agent work has been limited to scenarios where only a single contrast agent could be robustly detected within each voxel. We present a novel spectroscopic technique for de-mixing the spectral signal from multiple OCT contrast agents within a single voxel. We validate our technique in vitro and also demonstrate in vivo imaging of three spectrally distinct gold nanobipyramids, trafficking within the lymphatic system of a live mouse. This approach opens the door to a much broader range of pre-clinical and clinical OCT applications where multiplexed labeling is desirable.

scholarly journals In Vivo Imaging and Morphometry of the Human Pre-Descemet's Layer and Endothelium With Ultrahigh-Resolution Optical Coherence Tomography

2016 ◽  
Vol 57 (6) ◽  
pp. 2782 ◽  
Author(s):  
Kostadinka Bizheva ◽  
Lacey Haines ◽  
Erik Mason ◽  
Benjamin MacLellan ◽  
Bingyao Tan ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
In Vivo Imaging ◽  
Optical Coherence ◽  
Ultrahigh Resolution

Swept source optical coherence tomography for in vivo imaging and vibrometry in the apex of the mouse cochlea

2015 ◽  
Author(s):  
Hee Yoon Lee ◽  
Patrick D. Raphael ◽  
Audrey K. Ellerbee ◽  
Brian E. Applegate ◽  
John S. Oghalai
Keyword(s):  
Optical Coherence Tomography ◽  
In Vivo Imaging ◽  
Optical Coherence ◽  
Swept Source

In vivo imaging with high-speed full-range complex spectral domain optical coherence tomography

2005 ◽  
Author(s):  
Erich Goetzinger ◽  
Michael Pircher ◽  
Rainer A. Leitgeb ◽  
Adolf F. Fercher ◽  
Christoph K. Hitzenberger
Keyword(s):  
Optical Coherence Tomography ◽  
In Vivo Imaging ◽  
High Speed ◽  
Full Range ◽  
Spectral Domain ◽  
Optical Coherence

scholarly journals Scanning optical coherence tomography probe for in vivo imaging and displacement measurements in the cochlea

2019 ◽  
Vol 10 (2) ◽  
pp. 1032 ◽  
Author(s):  
Nathan C. Lin ◽  
Elika Fallah ◽  
C. Elliott Strimbu ◽  
Christine P. Hendon ◽  
Elizabeth S. Olson
Keyword(s):  
Optical Coherence Tomography ◽  
In Vivo Imaging ◽  
Optical Coherence ◽  
Displacement Measurements
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