Effect of the Arrangement of Optodes for 3D Diffuse Optical Tomography

2011 ◽  
Author(s):  
Kazuhiro Uchida ◽  
Shinpei Okawa ◽  
Kazuto Masamoto ◽  
Yoko Hoshi ◽  
Yukio Yamada
Keyword(s):  
Blood Volume ◽  
Wavelength Range ◽  
Near Infrared ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
High Quality ◽  
Tomographic Images ◽  
Infrared Wavelength ◽  
Optimum Arrangement ◽  
Simulation Results

Diffuse optical tomography (DOT) can obtain tomographic images of hemodynamics such as the oxygenation state and blood volume in tissues using light in the near infrared wavelength range where tissues absorb light weakly and oxy- and deoxy-hemoglobins show different absorbing characteristics. For 3D-DOT, much more optodes than those for 2D-DOT are desirable for high quality images. But practically the number of the optodes is limited and it is necessary to find the optimum arrangement of the optodes. This paper studies the effect of the optode arrangement on the reconstructed images by simulation of 3D-DOT when the number of the optodes is 16 and the object is a sphere with a diameter of 100 mm. Simulation results show that the optode arrangement which can effectively detect the light propagating through the target is important to reconstruct the target at the correct positions.

Time-Resolved Diffuse Optical Tomography of Human Forearm Under Exercise

2011 ◽  
Author(s):  
Yasuomi Endo ◽  
Yukari Tanikawa ◽  
Shinpei Okawa ◽  
Kazuto Masamoto ◽  
Hidetaka Okada ◽  
...  
Keyword(s):  
Near Infrared ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Biological Tissues ◽  
Magnetic Resonance Images ◽  
Time Resolved ◽  
Tomographic Images ◽  
Infrared Wavelength ◽  
Flexion And Extension ◽  
Absorption Characteristics

Light in the near-infrared wavelength range can penetrate deeping into biological tissues because the absorption by both water and hemoglobin is much smaller than in the other wavelength ranges. Oxygenated and deoxygenated hemoglobins have different light absorption characteristics. Therefore, by obtaining tomographic images of the absorption characteristics, it will be possible to know the hemodynamics inside deep tissues. Thus, the diffuse optical tomography (DOT) is expected as a new modality of biomedical imaging. In this study, we try to obtain DOT images of the forearms by conducting two types of exercise, and their differences caused by the muscle activity are discussed. By comparing the reconstructed DOT images with the magnetic resonance images of the forearm at the same position, the activated muscles can be identified in detail. As a result, the hemodynamics in the dominant muscles when performing flexion and extension of wrist are observed.

scholarly journals High-quality integrated microdisk resonators in the visible-to-near-infrared wavelength range on a 3C-silicon carbide-on-insulator platform

2019 ◽  
Vol 45 (1) ◽  
pp. 153 ◽  
Author(s):  
Tianren Fan ◽  
Xi Wu ◽  
Ali A. Eftekhar ◽  
Matteo Bosi ◽  
Hesam Moradinejad ◽  
...  
Keyword(s):  
Silicon Carbide ◽  
Wavelength Range ◽  
Near Infrared ◽  
High Quality ◽  
Infrared Wavelength ◽  
Microdisk Resonators

scholarly journals Design and implementation of a multifrequency near-infrared diffuse optical tomography system

2006 ◽  
Vol 11 (1) ◽  
pp. 014020 ◽  
Author(s):  
Gultekin Gulsen ◽  
Bin Xiong ◽  
Ozlem Birgul ◽  
Orhan Nalcioglu
Keyword(s):  
Near Infrared ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Design And Implementation ◽  
Tomography System

Hybridization-sensitive fluorescence control in the near-infrared wavelength range

2011 ◽  
Vol 9 (11) ◽  
pp. 4199 ◽  
Author(s):  
Shuji Ikeda ◽  
Hiroyuki Yanagisawa ◽  
Akiko Nakamura ◽  
Dan Ohtan Wang ◽  
Mizue Yuki ◽  
...  
Keyword(s):  
Wavelength Range ◽  
Near Infrared ◽  
Infrared Wavelength

scholarly journals Real-Time Dual-Wavelength Time-Resolved Diffuse Optical Tomography System for Functional Brain Imaging Based on Probe-Hosted Silicon Photomultipliers

Sensors ◽  
2020 ◽  
Vol 20 (10) ◽  
pp. 2815
Author(s):  
David Orive-Miguel ◽  
Laura Di Sieno ◽  
Anurag Behera ◽  
Edoardo Ferocino ◽  
Davide Contini ◽  
...  
Keyword(s):  
Brain Imaging ◽  
Near Infrared ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Brain Activation ◽  
Functional Brain Imaging ◽  
Dual Wavelength ◽  
Silicon Photomultipliers ◽  
Functional Brain ◽  
Tomography System

Near-infrared diffuse optical tomography is a non-invasive photonics-based imaging technology suited to functional brain imaging applications. Recent developments have proved that it is possible to build a compact time-domain diffuse optical tomography system based on silicon photomultipliers (SiPM) detectors. The system presented in this paper was equipped with the same eight SiPM probe-hosted detectors, but was upgraded with six injection fibers to shine the sample at several points. Moreover, an automatic switch was included enabling a complete measurement to be performed in less than one second. Further, the system was provided with a dual-wavelength (670 n m and 820 n m ) light source to quantify the oxy- and deoxy-hemoglobin concentration evolution in the tissue. This novel system was challenged against a solid phantom experiment, and two in-vivo tests, namely arm occlusion and motor cortex brain activation. The results show that the tomographic system makes it possible to follow the evolution of brain activation over time with a 1 s -resolution.

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