scholarly journals Rapid convergence to the inverse solution regularized with Lorentzian distributed function for near-infrared continuous wave diffuse optical tomography

2010 ◽  
Vol 15 (1) ◽  
pp. 016014 ◽  
Author(s):  
Min-Cheng Pan ◽  
Min-Chun Pan
Keyword(s):  
Near Infrared ◽  
Continuous Wave ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Inverse Solution ◽  
Rapid Convergence

Boundary Data Analysis of Continuous Wave Domain Diffuse Optical Tomography with Structured Refined Mesh Algorithm for Product Quality Control

2015 ◽  
Vol 771 ◽  
pp. 174-178
Author(s):  
Vebi Nadhira ◽  
Deddy Kurniadi ◽  
Endang Juliastuti ◽  
T. A. Yudha ◽  
Kurniadi Budiono
Keyword(s):  
Quality Control ◽  
Product Quality ◽  
Near Infrared ◽  
Continuous Wave ◽  
Infrared Detector ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Product Quality Control ◽  
Infrared Source ◽  
Boundary Parameter

Diffuse optical tomography is promising technology for non destructive evaluation on product quality control. In order to improve the forward sensitivity, structured refine mesh method was applied on continuous wave domain diffuse optical tomography imaging. This study was conducted on numerical and phantom object. These objects were illuminated by the near infrared source from object’s boundary. To obtain the boundary parameter data, a set of near infrared detector were placed on the periphery of the object. To validate our proposed forward analysis method, boundary parameter data of simulation are shown in comparison with that of experiment. In this study, we vary the position and the value of optical coefficient of defect on the object then we analyze the forward problem sensitivity. The result of this study indicated that continuous wave domain-diffuse optical tomography is promising for product quality control.

scholarly journals A Near-Infrared Optical Tomography System Based on Photomultiplier Tube

2007 ◽  
Vol 2007 ◽  
pp. 1-9 ◽  
Author(s):  
Huacheng Feng ◽  
Jing Bai ◽  
Xiaolei Song ◽  
Gang Hu ◽  
Junjie Yao
Keyword(s):  
Breast Cancer ◽  
Spectral Range ◽  
Near Infrared ◽  
Continuous Wave ◽  
Imaging System ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Experimental Results ◽  
Photomultiplier Tube ◽  
Tomography System

Diffuse optical tomography (DOT) is a rapidly growing discipline in recent years. It plays an important role in many fields, such as detecting breast cancer and monitoring the cerebra oxygenation. In this paper, a relatively simple, inexpensive, and conveniently used DOT system is presented in detail, in which only one photomultiplier tube is employed as the detector and an optical multiplexer is used to alter the detector channels. The 32-channel imager is consisted of 16-launch fibers and 16-detector fibers bundles, which works in the near-infrared (NIR) spectral range under continuous-wave (CW) model. The entire imaging system can work highly automatically and harmoniously. Experiments based on the proposed imaging system were performed, and the desired results can be obtained. The experimental results suggested that the proposed imaging instrumentation is effective.

Diffuse optical tomography to monitor the photocoagulation front during interstitial photothermal therapy: Numerical simulations and measurements in tissue-simulating phantoms

2014 ◽  
Vol 3 (3) ◽  
Author(s):  
Jie He ◽  
Brian C. Wilson ◽  
Daqing Piao ◽  
Robert Weersink
Keyword(s):  
Photothermal Therapy ◽  
Near Infrared ◽  
Continuous Wave ◽  
Diffusion Theory ◽  
Rectal Wall ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Optical Signal ◽  
Finite Element Software ◽  
Tissue Simulating Phantoms

AbstractNear-infrared interstitial photothermal therapy (PTT) is currently undergoing clinical trials as an alternative to watchful waiting or radical treatments in patients with low/intermediate-risk focal prostate cancer. Currently, magnetic resonance imaging (MRI)-based thermography is used to monitor thermal energy delivery and determine indirectly the completeness of the target tumor destruction while avoiding damage to adjacent normal tissues, particularly the rectal wall. As an alternative, transrectal diffuse optical tomography (TRDOT) is being developed to image directly the photocoagulation boundary based on the changes in tissue optical properties, particularly scattering. An established diffusion-theory finite-element software platform was used to perform forward simulations to determine the sensitivity of changes in the optical signal resulting from a growing coagulated lesion with optical scattering contrast, for varying light source-detector separations in both longitudinal and transverse imaging geometries. The simulations were validated experimentally in tissue-simulating phantoms using an existing continuous-wave TRDOT system, in a configuration that is representative of one potential intended clinical use. This provides critical guidance for the optimum design of the transrectal applicator probe, in terms of achieving maximum sensitivity to the presence of the coagulation boundary and, consequently, the highest accuracy in determining the boundary location relative to the rectal wall.

scholarly journals Design and implementation of a multifrequency near-infrared diffuse optical tomography system

2006 ◽  
Vol 11 (1) ◽  
pp. 014020 ◽  
Author(s):  
Gultekin Gulsen ◽  
Bin Xiong ◽  
Ozlem Birgul ◽  
Orhan Nalcioglu
Keyword(s):  
Near Infrared ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Design And Implementation ◽  
Tomography System

scholarly journals Real-Time Dual-Wavelength Time-Resolved Diffuse Optical Tomography System for Functional Brain Imaging Based on Probe-Hosted Silicon Photomultipliers

Sensors ◽  
2020 ◽  
Vol 20 (10) ◽  
pp. 2815
Author(s):  
David Orive-Miguel ◽  
Laura Di Sieno ◽  
Anurag Behera ◽  
Edoardo Ferocino ◽  
Davide Contini ◽  
...  
Keyword(s):  
Brain Imaging ◽  
Near Infrared ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Brain Activation ◽  
Functional Brain Imaging ◽  
Dual Wavelength ◽  
Silicon Photomultipliers ◽  
Functional Brain ◽  
Tomography System

Near-infrared diffuse optical tomography is a non-invasive photonics-based imaging technology suited to functional brain imaging applications. Recent developments have proved that it is possible to build a compact time-domain diffuse optical tomography system based on silicon photomultipliers (SiPM) detectors. The system presented in this paper was equipped with the same eight SiPM probe-hosted detectors, but was upgraded with six injection fibers to shine the sample at several points. Moreover, an automatic switch was included enabling a complete measurement to be performed in less than one second. Further, the system was provided with a dual-wavelength (670 n m and 820 n m ) light source to quantify the oxy- and deoxy-hemoglobin concentration evolution in the tissue. This novel system was challenged against a solid phantom experiment, and two in-vivo tests, namely arm occlusion and motor cortex brain activation. The results show that the tomographic system makes it possible to follow the evolution of brain activation over time with a 1 s -resolution.

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