Time-Resolved Echo-Particle Image/Tracking Velocimetry Measurement of Interactions Between Native Cardiac Output and Veno-Arterial ECMO Flows

2020 ◽  
Vol 143 (2) ◽  
Author(s):  
Zeng Zhang ◽  
Xun Zhou ◽  
Alejandro Suarez-Pierre ◽  
Cecillia Lui ◽  
Sean Kearney ◽  
...  
Keyword(s):  
Cardiac Output ◽  
Flow Rate ◽  
Aortic Root ◽  
Particle Image ◽  
Blind Deconvolution ◽  
Secondary Flows ◽  
Time Resolved ◽  
Image Tracking ◽  
The Impact ◽  
Ecmo Flow

Abstract Determination of optimal hemodynamic and pressure–volume loading conditions for patients undergoing veno-arterial extracorporeal membrane oxygenation (VA-ECMO) would benefit from understanding the impact of ECMO flow rates (QE) on the native cardiac output in the admixing zone, i.e., aortic root. This study characterizes the flow in the aortic root of a pig with severe myocardial ischemia using contrast-enhanced ultrasound particle image/tracking velocimetry (echo-PIV/PTV). New methods for data preprocessing are introduced, including autocontouring to remove surrounding tissues, followed by blind deconvolution to identify the centers of elongated bubble traces in images with low signal to noise ratio. Calibrations based on synthetic images show that this procedure increases the number of detected bubbles and reduces the error in their locations by 50%. Then, an optimized echo-PIV/PTV procedure, which integrates image enhancement with velocity measurements, is used for characterizing the time-resolved two-dimensional (2D) velocity distributions. Phase-averaged and instantaneous flow fields show that the ECMO flow rate influences the velocity and acceleration of the cardiac output during systole, and secondary flows during diastole. When QE is 3.0 L/min or higher, the cardiac ejection velocity, phase interval with open aortic valve, velocity-time integral (VTI), and mean arterial pressure (MAP) increase with decreasing QE, all indicating sufficient support. For lower QE, the MAP and VTI decrease as QE is reduced, and the deceleration during transition to diastole becomes milder. Hence, for this specific case, the optimal ECMO flow rate is 3.0 L/min.

Effect of Hot Streak Migration on Unsteady Blade Row Interaction in an Axial Turbine

2012 ◽  
Vol 134 (5) ◽  
Author(s):  
P. Jenny ◽  
C. Lenherr ◽  
R. S. Abhari ◽  
A. Kalfas
Keyword(s):  
Hot Spot ◽  
Fast Response ◽  
Secondary Flows ◽  
Inlet Temperature ◽  
Time Resolved ◽  
Axial Turbine ◽  
Blade Row ◽  
Hot Streak ◽  
The Impact ◽  
Blade Row Interaction

This paper presents an experimental study of the effect of unsteady blade row interaction on the migration of hot streaks in an axial turbine. The hot streaks can cause localized hot spots on the blade surfaces in a high-pressure turbine, leading to high heat loads and potentially catastrophic failure of the blades. An improved understanding of the effect of unsteady blade row interaction on an inlet temperature distortion is of crucial importance. The impact of hot streaks on the aerodynamic performance of a turbine stage is also not well understood. In the current experiment, the influence of hot streaks on a highly loaded 1.5-stage unshrouded model axial turbine is studied. A hot streak generator has been developed specifically for this project to introduce hot streaks that match the dimensional parameters of real engines. The temperature profile, spanwise position, circumferential position, and cross-section shape of the hot streak can be independently varied. The recently developed ETH Zurich two-sensor high temperature (260 °C) fast response aerodynamic probe (FRAP) technique and the fast response entropy. Probe (FENT) systems are used in this experimental campaign. Time resolved measurements of the unsteady pressure, temperature, and entropy are made at the NGV inlet and between the rotor and stator blade rows. From the nozzle guide vane inlet to outlet the measurements show a reduction in the maximum relative entropy difference between the free stream and the hot spot of 30% for the highest temperature gases in the core of the hot streak, indicating a region of heat loss. Time resolved flow field measurements at the rotor exit based on both measurement methods showed the hot gases traveling towards the hub and tip casing on the blade pressure side and interacting with secondary flows such as the hub passage vortex.

Large Eddy Simulations of Static and Rotating Ribbed Channels in Adiabatic and Isothermal Conditions

2017 ◽  
Author(s):  
Thomas Grosnickel ◽  
Florent Duchaine ◽  
Laurent Y. M. Gicquel ◽  
Charlie Koupper
Keyword(s):  
Flow Direction ◽  
Secondary Flows ◽  
Flow Topology ◽  
Time Resolved ◽  
Piv Measurements ◽  
Eddy Simulation ◽  
Image Velocimetry ◽  
Large Eddy ◽  
Rib Turbulators ◽  
The Impact

In an attempt to better understand spatially developing rotating cooling flows, the present study focuses on a computational investigation of a straight, rotating rib roughened cooling channel initially numerically studied by Fransen et al. [1]. The configuration consists of a squared channel equipped with 8 rib turbulators placed with an angle of 90 degrees with respect to the flow direction. The rib pitch-to-height (p/h) ratio is 10 and the height-to-hydraulic diameter (h/Dh) ratio is 0.1. The simulations are based on a case where time resolved two-dimensional Particle Image Velocimetry (PIV) measurements have been performed at the Von Karman Institute (VKI) in a near gas turbine operating condition: the Reynolds number (Re) and the rotation number (Ro) are around 15000 and ± 0.38 respectively. Adiabatic as well as anisothermal conditions have been investigated to evaluate the impact of the wall temperature on the flow, especially in the rotating configurations. Static as well as both positive and negative rotating channels are compared with experimental data. In each case, either an adiabatic or an isothermal wall boundary condition can be computed. In this work, Large Eddy Simulation (LES) results show that the high fidelity CFD model manages very well the turbulence increase (decrease) around the rib in destabilizing (stabilizing) rotation of the ribbed channels. Thanks to the full spatial and temporal description produced by LES, the spatial development of secondary flows are found to be at the origine of observed differences with experimental measurements. Finally, the model is also able to reproduce the differences induced by buoyancy on the flow topology in the near rib region and resulting from an anisothermal flow in rotation.

Validating the Numerical Prediction of the Aerodynamics of an Axial Compressor

2014 ◽  
Author(s):  
Torben Wolff ◽  
Florian Herbst ◽  
Oliver Freund ◽  
Le Liu ◽  
Joerg R. Seume
Keyword(s):  
Pressure Ratio ◽  
Three Dimensional ◽  
Axial Compressor ◽  
Secondary Flows ◽  
Time Resolved ◽  
Prediction Quality ◽  
Numerical Predictions ◽  
Turbomachinery Design ◽  
The Impact

Numerical methods have become the basis for the aerodynamic design of turbomachinery in order to reduce the time for development cycles and associated cost. Designing modern axial compressors requires high confidence in the quality of numerical predictions. In terms of the aerodynamics, the loading of the blades as well as the efficiency targets constantly increase. Losses have to be predicted precisely and the impact of three-dimensional secondary flows, separation, and laminar-turbulent transition must be taken into account. In the present paper, the aerodynamic prediction quality of the state-of-the-art turbomachinery design code TRACE is validated against experimental data from a 2.5-stage axial compressor. The aerodynamic prediction quality is systematically investigated to determine errors and uncertainties regarding the discretization, turbulence and transition models, and importance of considering unsteady effects. Computations are performed for several operating points and the results are validated by means of the compressors integral pressure ratio as well as by means of local pneumatic probe measurements. It is shown that using the empirical γ–ReΘ model improves the prediction quality of the boundary layers and wake flows. Time-resolved computations at the design point of the compressor show that the strength and the losses of a corner separation in both vane rows are reduced to realistic levels when the periodic-unsteady interaction with the upstream wakes is considered. The generally good aerodynamic predictions for both local and integral experimental quantities qualify TRACE for aeroelastic predictions which are planned for the future.

Effect of Hot Streak Migration on Unsteady Blade Row Interaction in an Axial Turbine

2010 ◽  
Author(s):  
P. Jenny ◽  
C. Lenherr ◽  
A. Kalfas ◽  
R. S. Abhari
Keyword(s):  
Hot Spot ◽  
Fast Response ◽  
Secondary Flows ◽  
Inlet Temperature ◽  
Time Resolved ◽  
Axial Turbine ◽  
Blade Row ◽  
Hot Streak ◽  
The Impact ◽  
Blade Row Interaction

This paper presents an experimental study of the effect of unsteady blade row interaction on the migration of hot streaks in an axial turbine. The hot streaks can cause localised hot spots on the blade surfaces in a high-pressure turbine, leading to high heat loads and potentially catastrophic failure of the blades. An improved understanding of the effect of unsteady blade row interaction on an inlet temperature distortion is of crucial importance. The impact of hot streaks on the aerodynamic performance of a turbine stage is also not well understood. In the current experiment, the influence of hot streaks on a highly loaded one-and-half-stage unshrouded model axial turbine is studied. A hot streak generator has been developed specifically for this project to introduce hot streaks that match the dimensional parameters of real engines. The temperature profile, spanwise position, circumferential position and cross-section shape of the hot streak can be independently varied. The recently developed ETH Zurich 2-sensor high temperature (260°C) Fast Response Aerodynamic Probe (FRAP) technique and the Fast Response Entropy Probe (FENT) systems are used in this experimental campaign. Time resolved measurements of the unsteady pressure, temperature and entropy are made at the NGV inlet and between the rotor and stator blade rows. From the nozzle guide vane inlet to outlet the measurements show a reduction in the maximum relative entropy difference between the free stream and the hot spot of 30% for the highest temperature gases in the core of the hot streak, indicating a region of heat loss. Time resolved flow field measurements at the rotor exit based on both measurement methods showed the hot gases travelling towards the hub and tip casing on the blade pressure side and interacting with secondary flows such as the hub passage vortex.

Impact Of Transurethral Resection Of Prostate On International Prostate Symptom Score And Peak Urinary Flow Rate

2020 ◽  
Vol 16 (1) ◽  
pp. 11-15
Author(s):  
Md Waliul Islam ◽  
Md Abul Hossain ◽  
Md Nurul Hooda ◽  
Kazi Rafiqul Abedin ◽  
Husne Ara
Keyword(s):  
Flow Rate ◽  
Transurethral Resection ◽  
Urine Volume ◽  
T Test ◽  
Urinary Symptoms ◽  
Urinary Flow Rate ◽  
Transurethral Resection Of Prostate ◽  
Urinary Flow ◽  
Paired Student ◽  
The Impact

Objectives: To evaluate urinary symptoms and quality of life in patient with BPH before and after TURP. To determine the impact of TURP on the urinary symptoms (IPSS) and peak urinary flow rate. Methods: This study is prospective study carried out between 2010 and 2011 in the department of Urology, National Institute of Kidney Diseases & Urology. Total 102 cases were selected purposively according to selection criteria. Each patient was observed and followed up at 8 weeks (1st visit), 16 weeks (2nd visit) 24 weeks (3rd visit) after transurethral resection of prostate (TURP). IPSS score, QOL score also recorded and uroflowmetry was done to see the peak urinary flow rate (Qmax) of urine and voiding time. USG was done to see post voidal residual urine volume and DRE also done in selected cases. Data was complied and statistical analysis were done using computer based software, Statistical Package for Social Science (SPSS), using paired ‘t’ test. A P value <0.05 was taken as significance. Results: Before TURP, IPSS range 17-25 and mean 21.61+2.43, after TURP, range 0-7 and mean 4.27+1.71). Hence a significant improvement of IPSS was found from 2 months to 6 months follow up after TURP. The change was tested using “paired student ‘t’ test”. Before TURP Qmax range 7-12.2 and mean was 9.96+1.69, which became range 18-25 and mean was 22.61+2.28 after TURP and therefore change of mean Qmax was 12.64+2.69. The change was tested using “paired student ‘t’ test”. The change was found significant (P<0.001). Conclusion: Transurethral resection of prostate resolves obstructive symptoms, rapid improvement of urinary flow rate Bangladesh Journal of Urology, Vol. 16, No. 1, Jan 2013 p.11-15

scholarly journals Model of thermal buoyancy in cavity-ventilated roof constructions

2021 ◽  
pp. 174425912098418
Author(s):  
Toivo Säwén ◽  
Martina Stockhaus ◽  
Carl-Eric Hagentoft ◽  
Nora Schjøth Bunkholt ◽  
Paula Wahlgren
Keyword(s):  
Analytical Model ◽  
Flow Rate ◽  
Numerical Study ◽  
Air Flow ◽  
Wind Pressure ◽  
Air Flow Rate ◽  
Test Set ◽  
Air Cavity ◽  
Thermal Buoyancy ◽  
The Impact

Timber roof constructions are commonly ventilated through an air cavity beneath the roof sheathing in order to remove heat and moisture from the construction. The driving forces for this ventilation are wind pressure and thermal buoyancy. The wind driven ventilation has been studied extensively, while models for predicting buoyant flow are less developed. In the present study, a novel analytical model is presented to predict the air flow caused by thermal buoyancy in a ventilated roof construction. The model provides means to calculate the cavity Rayleigh number for the roof construction, which is then correlated with the air flow rate. The model predictions are compared to the results of an experimental and a numerical study examining the effect of different cavity designs and inclinations on the air flow rate in a ventilated roof subjected to varying heat loads. Over 80 different test set-ups, the analytical model was found to replicate both experimental and numerical results within an acceptable margin. The effect of an increased total roof height, air cavity height and solar heat load for a given construction is an increased air flow rate through the air cavity. On average, the analytical model predicts a 3% higher air flow rate than found in the numerical study, and a 20% lower air flow rate than found in the experimental study, for comparable test set-ups. The model provided can be used to predict the air flow rate in cavities of varying design, and to quantify the impact of suggested roof design changes. The result can be used as a basis for estimating the moisture safety of a roof construction.

scholarly journals Research on the impact of ship traffic flow on the restricted channel segment of the middle Yangtze River based on traffic wave theory

2021 ◽  
Vol 3 (8) ◽  
Author(s):  
Ting Liu ◽  
Gabriel Lodewijks
Keyword(s):  
Traffic Flow ◽  
Flow Rate ◽  
Flow Simulation ◽  
Wave Theory ◽  
Flow Density ◽  
List Type ◽  
Ship Traffic ◽  
Traffic Wave ◽  
The Impact ◽  
Channel Segment

Abstract Abstract On the basis of the influence of dry season on ship traffic flow, the gathering and dissipating process of ship traffic flow was researched with Greenshields linear flow—density relationship model, the intrinsic relationship between the ship traffic congestion state and traffic wave in the unclosed restricted channel segment was emphatically explored when the ship traffic flow in a tributary channel inflows, and the influence law of multiple traffic waves on the ship traffic flow characteristics in unclosed restricted segment is revealed. On this basis, the expressions of traffic wave speed and direction, dissipation time of queued ships and the number of ships affected were provided, and combined with Monte Carlo method, the ship traffic flow simulation model in the restricted channel segment was built. The simulation results show that in closed restricted channel segment the dissipation time of ships queued is mainly related to the ship traffic flow rate of segments A and C, and the total number of ships affected to the ship traffic flow rate of segment A. And in unclosed restricted channel segment, the dissipation time and the total number of ships affected are also determined by the meeting time of the traffic waves in addition to the ship traffic flow rate of segments. The research results can provide the theoretical support for further studying the ship traffic flow in unclosed restricted channel segment with multiple tributaries Article Highlights The inflow of tributaries' ship traffic flows has an obvious impact on the traffic conditions in the unenclosed restricted channel segment. The interaction and influence between multiple ship traffic waves and the mechanism of generating new traffic waves are explained. The expression of both dissipation time of queued ships and the total number of ships affected in the closed and unclosed restricted channel segment are given.

scholarly journals Time-resolved particle image velocimetry measurements of the turbulent Richtmyer–Meshkov instability

2021 ◽  
Vol 917 ◽  
Author(s):  
Everest G. Sewell ◽  
Kevin J. Ferguson ◽  
Vitaliy V. Krivets ◽  
Jeffrey W. Jacobs
Keyword(s):  
Particle Image Velocimetry ◽  
Particle Image ◽  
Time Resolved ◽  
Image Velocimetry

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