An Automated Kinematic Measurement System for Sagittal Plane Murine Head Impacts

2020 ◽  
Vol 142 (8) ◽  
Author(s):  
Kurt A. McInnes ◽  
Zelalem A. Abebe ◽  
Thomas Whyte ◽  
Asma Bashir ◽  
Carlos Barron ◽  
...  
Keyword(s):  
High Speed ◽  
Brain Injuries ◽  
Sagittal Plane ◽  
Tracking System ◽  
Head Impact ◽  
Percentage Error ◽  
Head Tracking ◽  
Rigid Fixation ◽  
Head Impacts ◽  
The Brain

Abstract Mild traumatic brain injuries are typically caused by nonpenetrating head impacts that accelerate the skull and result in deformation of the brain within the skull. The shear and compressive strains caused by these deformations damage neural and vascular structures and impair their function. Accurate head acceleration measurements are necessary to define the nature of the insult to the brain. A novel murine head tracking system was developed to improve the accuracy and efficiency of kinematic measurements obtained with high-speed videography. A three-dimensional (3D)-printed marker carrier was designed for rigid fixation to the upper jaw and incisors with an elastic strap around the snout. The system was evaluated by impacting cadaveric mice with the closed head impact model of engineered rotational acceleration (CHIMERA) system using an energy of 0.7 J (5.29 m/s). We compared the performance of the head-marker system to the previously used skin-tracking method and documented significant improvements in measurement repeatability (aggregate coefficient of variation (CV) within raters from 15.8 to 1.5 and between raters from 15.5 to 1.5), agreement (aggregate percentage error from 24.9 to 8.7), and temporal response (aggregate temporal curve agreement from 0.668 to 0.941). Additionally, the new system allows for automated software tracking, which dramatically decreases the analysis time required (74% reduction). This novel head tracking system for mice offers an efficient, reliable, and real-time method to measure head kinematics during high-speed impacts using CHIMERA or other rodent or small mammal head impact models.

Head Kinematics in Mini-Sled Tests of Foam Padding: Relevance of Linear Responses From Free Motion Headform (FMH) Testing to Head Angular Responses

2003 ◽  
Vol 125 (4) ◽  
pp. 523-532 ◽  
Author(s):  
J. Ivarsson ◽  
D. C. Viano ◽  
P. Lo¨vsund ◽  
Y. Parnaik
Keyword(s):  
Angular Velocity ◽  
Brain Injuries ◽  
Motor Vehicle ◽  
Sagittal Plane ◽  
Angular Acceleration ◽  
Linear Acceleration ◽  
Free Motion ◽  
Constant Thickness ◽  
Head Impacts ◽  
Hybrid Iii

The revised Federal Motor Vehicle Safety Standard (FMVSS) No. 201 specifies that the safety performance of vehicle upper interiors is determined from the resultant linear acceleration response of a free motion headform (FMH) impacting the interior at 6.7 m/s. This study addresses whether linear output data from the FMH test can be used to select an upper interior padding that decreases the likelihood of rotationally induced brain injuries. Using an experimental setup consisting of a Hybrid III head-neck structure mounted on a mini-sled platform, sagittal plane linear and angular head accelerations were measured in frontal head impacts into foam samples of various stiffness and density with a constant thickness (51 mm) at low (∼5.0 m/s), intermediate (∼7.0 m/s), and high (∼9.6 m/s) impact speeds. Provided that the foam samples did not bottom out, recorded peak values of angular acceleration and change in angular velocity increased approximately linearly with increasing peak resultant linear acceleration and value of the Head Injury Criterion HIC36. The results indicate that the padding that produces the lowest possible peak angular acceleration and peak change in angular velocity without causing high peak forces is the one that produces the lowest possible HIC36 without bottoming out in the FMH test.

Arachnoid Trabeculae and CSF Roles in Blunt Head Impacts

2003 ◽  
Author(s):  
M. Zoghi-Moghadam ◽  
Ali Sadegh ◽  
Charles Watkins
Keyword(s):  
Cerebrospinal Fluid ◽  
Relative Motion ◽  
Brain Injuries ◽  
Shear Stresses ◽  
Two Dimensional ◽  
Global Models ◽  
Contact Sports ◽  
Head Impacts ◽  
The Brain

The blunt head impacts due to vehicular collisions, contact sports or falls cause relative motion between the brain and skull and an increase in contact and shear stresses in meningeal region. Several models have been developed to better understand brain injuries. In this study the mechanical role of the fibrous trabeculae and the Cerebrospinal Fluid (CSF) in Subarachnoid space (SAS) is investigated. Two-dimensional solid and fluid global models of the head and a local model of the SAS trabeculae were developed. The CSF pressure distribution and the trabeculae deformations were determined. It is concluded that the arachnoid trabeculae reduce the pressure in the CSF and both play a major role in damping the blunt head impact.

High-speed active head tracking system

2014 ◽  
Author(s):  
V. Markov ◽  
S. A. Kupiec ◽  
A. Hastings ◽  
T. Hester
Keyword(s):  
High Speed ◽  
Tracking System ◽  
Head Tracking

scholarly journals Reconstruction of head impacts in FIS World Cup alpine skiing

2017 ◽  
Vol 52 (11) ◽  
pp. 709-715 ◽  
Author(s):  
Sophie Elspeth Steenstrup ◽  
Kam-Ming Mok ◽  
Andrew S McIntosh ◽  
Roald Bahr ◽  
Tron Krosshaug
Keyword(s):  
Head Injury ◽  
Sagittal Plane ◽  
Two Dimensions ◽  
Head Impact ◽  
World Cup ◽  
Injury Surveillance System ◽  
Velocity Change ◽  
Head Impacts ◽  
Impact Biomechanics ◽  
Testing Speed

IntroductionPrior to the 2013/2014 season, the International Ski Federation (FIS) increased the helmet testing speed from 5.4 to 6.8 m/s for alpine downhill, super-G and giant slalom. Whether this increased testing speed reflects head impact velocities in real head injury situations on snow is unclear. We therefore investigated the injury mechanisms and gross head impact biomechanics in seven real head injury situations among World Cup (WC) alpine skiers.MethodsWe analysed nine head impacts from seven head injury videos from the FIS Injury Surveillance System, throughout nine WC seasons (2006–2015) in detail. We used commercial video-based motion analysis software to estimate head impact kinematics in two dimensions, including directly preimpact and postimpact, from broadcast video. The sagittal plane angular movement of the head was also measured using angle measurement software.ResultsIn seven of nine head impacts, the estimated normal to slope preimpact velocity was higher than the current FIS helmet rule of 6.8 m/s (mean 8.1 (±SD 0.6) m/s, range 1.9±0.8 to 12.1±0.4 m/s). The nine head impacts had a mean normal to slope velocity change of 9.3±1.0 m/s, range 5.2±1.1 to 13.5±1.3 m/s. There was a large change in sagittal plane angular velocity (mean 43.3±2.9 rad/s (range 21.2±1.5 to 64.2±3.0 rad/s)) during impact.ConclusionThe estimated normal to slope preimpact velocity was higher than the current FIS helmet rule of 6.8 m/s in seven of nine head impacts.

scholarly journals Subconcussive brain vital signs changes predict head-impact exposure in ice hockey players

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Shaun D Fickling ◽  
Aynsley M Smith ◽  
Michael J Stuart ◽  
David W Dodick ◽  
Kyle Farrell ◽  
...  
Keyword(s):  
Cognitive Processing ◽  
Vital Sign ◽  
Brain Function ◽  
Point Of Care ◽  
Vital Signs ◽  
Head Impact ◽  
Ice Hockey ◽  
Head Impacts ◽  
Hockey Players ◽  
The Brain

Abstract The brain vital signs framework is a portable, objective, neurophysiological evaluation of brain function at point-of-care. We investigated brain vital signs at pre- and post-season for age 14 or under (Bantam) and age 16–20 (Junior-A) male ice hockey players to (i) further investigate previously published brain vital sign results showing subconcussive cognitive deficits and (ii) validate these findings through comparison with head-impact data obtained from instrumented accelerometers. With a longitudinal study design, 23 male ice hockey players in Bantam (n = 13; age 13.63 ± 0.62) and Tier II Junior-A (n = 10; age 18.62 ± 0.86) divisions were assessed at pre- and post-season. None were diagnosed with a concussion during the season. Cognitive evoked potential measures of Auditory sensation (N100), Basic attention (P300) and Cognitive processing (N400) were analysed as changes in peak amplitudes and latencies (six standard scores total). A regression analysis examined the relationship between brain vital signs and the number of head impacts received during the study season. Significant pre/post differences in brain vital signs were detected for both groups. Bantam and Junior-A players also differed in number of head impacts (Bantam: 32.92 ± 17.68; Junior-A: 195.00 ± 61.08; P < 0.001). Importantly, the regression model demonstrated a significant linear relationship between changes in brain vital signs and total head impacts received (R = 0.799, P = 0.007), with clear differences between the Bantam and Junior-A groups. In the absence of a clinically diagnosed concussion, the brain vital sign changes appear to have demonstrated the compounding effects of repetitive subconcussive impacts. The findings underscored the importance of an objective physiological measure of brain function along the spectrum of concussive impacts.

Brain Tumor Detection via Asymmetry Quantification across Mid Sagittal Plane

2020 ◽  
Vol 13 ◽  
Author(s):  
Shoaib Amin Banday ◽  
Mohammad Khalid Pandit
Keyword(s):  
Brain Tumor ◽  
Brain Tumors ◽  
Sagittal Plane ◽  
Early Stage ◽  
Imaging Techniques ◽  
Complex Structure ◽  
Magnetic Resonance Images ◽  
Absolute Difference ◽  
Brain Hemispheres ◽  
The Brain

Introduction: Brain tumor is among the major causes of morbidity and mortality rates worldwide. According to National Brain Tumor Foundation (NBTS), the death rate has nearly increased by as much as 300% over last couple of decades. Tumors can be categorized as benign (non-cancerous) and malignant (cancerous). The type of the brain tumor significantly depends on various factors like the site of its occurrence, its shape, the age of the subject etc. On the other hand, Computer Aided Detection (CAD) has been improving significantly in recent times. The concept, design and implementation of these systems ascend from fairly simple ones to computationally intense ones. For efficient and effective diagnosis and treatment plans in brain tumor studies, it is imperative that an abnormality is detected at an early stage as it provides a little more time for medical professionals to respond. The early detection of diseases has predominantly been possible because of medical imaging techniques developed from past many decades like CT, MRI, PET, SPECT, FMRI etc. The detection of brain tumors however, has always been a challenging task because of the complex structure of the brain, diverse tumor sizes and locations in the brain. Method: This paper proposes an algorithm that can detect the brain tumors in the presence of the Radio-Frequency (RF) inhomoginiety. The algorithm utilizes the Mid Sagittal Plane as a landmark point across which the asymmetry between the two brain hemispheres is estimated using various intensity and texture based parameters. Result: The results show the efficacy of the proposed method for the detection of the brain tumors with an acceptable detection rate. Conclusion: In this paper, we have calculated three textural features from the two hemispheres of the brain viz: Contrast (CON), Entropy (ENT) and Homogeneity (HOM) and three parameters viz: Root Mean Square Error (RMSE), Correlation Co-efficient (CC), and Integral of Absolute Difference (IAD) from the intensity distribution profiles of the two brain hemispheres to predict any presence of the pathology. First a Mid Sagittal Plane (MSP) is obtained on the Magnetic Resonance Images that virtually divides brain into two bilaterally symmetric hemispheres. The block wise texture asymmetry is estimated for these hemispheres using the above 6 parameters.

Methyl jasmonate delays the latency to anoxic convulsions by normalizing the brain levels of oxidative stress biomarkers and serum corticosterone contents in mice with repeated anoxic stress

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Abayomi Ololade Adelaja ◽  
Oluwafemi Gabriel Oluwole ◽  
Oritoke Modupe. Aluko ◽  
Solomon Umukoro
Keyword(s):  
Oxidative Stress ◽  
Blood Glucose ◽  
Methyl Jasmonate ◽  
Brain Injuries ◽  
Antioxidant Property ◽  
Oxidative Stress Biomarkers ◽  
Serum Corticosterone ◽  
Stress Agent ◽  
Cellular Antioxidants ◽  
The Brain

AbstractObjectivesRepeated exposure to anoxic stress damages the brain through cortisol-mediated increases in oxidative stress and cellular-antioxidants depletion. Thus, compounds with antioxidant property might confer protection against anoxic stress-induced brain injuries. In this study, we further examined the protective effect of methyl jasmonate (MJ), a potent anti-stress agent against anoxic stress-induced convulsions in mice.MethodsThirty-six male Swiss mice randomized into six groups (n=6) were given MJ (25, 50 and 100 mg/kg, i.p.) or vehicle (10 mL/kg, i.p.) 30 min before 15 min daily exposure to anoxic stress for 7 days. The latency(s) to anoxic convulsion was recorded on day 7. The blood glucose and serum corticosterone levels were measured afterwards. The brains were also processed for the determination of malondialdehyde, nitrite, and glutathione levels.ResultsMethyl jasmonate (MJ) delayed the latency to anoxic convulsion and reduced the blood glucose and serum corticosterone levels. The increased malondialdehyde and nitrite contents accompanied by decreased glutathione concentrations in mice with anoxic stress were significantly attenuated by MJ.ConclusionsThese findings further showed that MJ possesses anti-stress property via mechanisms relating to the reduction of serum contents of corticosterone and normalization of brain biomarker levels of oxidative stress in mice with anoxic stress.

Do elite soccer players cover longer distance when losing? Differences between attackers and defenders

2020 ◽  
pp. 174795412098227
Author(s):  
Carlos Lago-Peñas ◽  
Anton Kalén ◽  
Miguel Lorenzo-Martinez ◽  
Roberto López-Del Campo ◽  
Ricardo Resta ◽  
...  
Keyword(s):  
New York ◽  
High Speed ◽  
Large Scale ◽  
Tracking System ◽  
Soccer Players ◽  
Running Performance ◽  
Situational Variables ◽  
Total Distance ◽  
Professional Soccer ◽  
Score Line

This study aimed to evaluate the effects playing position, match location (home or away), quality of opposition (strong or weak), effective playing time (total time minus stoppages), and score-line on physical match performance in professional soccer players using a large-scale analysis. A total of 10,739 individual match observations of outfield players competing in the Spanish La Liga during the 2018–2019 season were recorded using a computerized tracking system (TRACAB, Chyronhego, New York, USA). The players were classified into five positions (central defenders, players = 94; external defenders, players = 82; central midfielders, players = 101; external midfielders, players = 72; and forwards, players = 67) and the following match running performance categories were considered: total distance covered, low-speed running (LSR) distance (0–14 km · h−1), medium-speed running (MSR) distance (14–21 km · h−1), high-speed running (HSR) distance (>21 km · h−1), very HSR (VHSR) distance (21–24 km · h−1), sprint distance (>24 km · h−1) Overall, match running performance was highly dependent on situational variables, especially the score-line condition (winning, drawing, losing). Moreover, the score-line affected players running performance differently depending on their playing position. Losing status increased the total distance and the distance covered at MSR, HSR, VHSR and Sprint by defenders, while attacking players showed the opposite trend. These findings may help coaches and managers to better understand the effects of situational variables on physical performance in La Liga and could be used to develop a model for predicting the physical activity profile in competition.

Effects of shoulder translation on lumbar moment for two dimensional modeling strategies during lifting

1998 ◽  
Vol 1 (3) ◽  
pp. 173-187
Author(s):  
Wayne J. Albert ◽  
Joan M. Stevenson ◽  
Geneviève A. Dumas ◽  
Roger W. Wheeler
Keyword(s):  
Sagittal Plane ◽  
Tracking System ◽  
Vertical Direction ◽  
Two Dimensional ◽  
Model Type ◽  
Trunk Acceleration ◽  
Analysis System ◽  
Trunk Orientation ◽  
Shoulder Position ◽  
Dynamic Link

The objectives of this study were to: 1) develop a dynamic 2D link segment model for lifting using the constraints of four sensors from an electromagnetic motion analysis system; 2) evaluate the magnitude of shoulder movement in the sagittal plane during lifting; and 3) investigate the effect of shoulder translation on trunk acceleration and lumbar moments calculated by the developed model and comparing it with two separate 2D dynamic link segment models. Six women and six men lifted loads of 2 kg, 7 kg, 12 kg and 2 kg, 12 kg, 22 kg respectively, under stoop, squat and freestyle conditions. Trunk orientation and position, as well as shoulder position were monitored during all lifts using the Polhemus FASTRAK\trdmk. Results indicated that average range of motion was 0.05 ± 0.02 m in the horizontal direction and 0.03 ± 0.02 m in the vertical direction. Shoulder position relative to T1 was located 0.07 ± 0.02 m anteriorly, and 0.02 ± 0.04 m superiorly (0.06 and 0.00 m for males and 0.08 and 0.04 m for females, respectively). To estimate the effect of shoulder motion on trunk acceleration and L5/S1 moments, three two-dimensional dynamic link segment models were developed within the constraints of the electromagnetic tracking system and compared. Trunk segment endpoints were defined as L5/S1 and either T1 or shoulder depending on model type. For trunk accelerations, average differences between models were greater than 40 deg/s² in 70.4% trunk accelerations did not translate into significantly different moment calculations between models. Average peak dynamic L5/S1 moment differences between models were smaller than 4 Nm for all lifting conditions which failed to be statistically significant (p>0.05). The model type did not have a statistically significant effect on peak L5/S1 moments. Therefore, despite important shoulder joint translations, peak L5/S1 moments were not significantly affected.

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