Investigation of the Effect of Geometric Parameters on EWOD Actuation in Rectangular Microchannels

2018 ◽  
Vol 140 (9) ◽  
Author(s):  
Sajad Pooyan ◽  
Mohammad Passandideh-Fard
Keyword(s):  
Theoretical Model ◽  
High Speed ◽  
Channel Width ◽  
Circuit Board ◽  
Design Parameters ◽  
Channel Height ◽  
Liquid Slug ◽  
Electrowetting On Dielectric ◽  
Transport Velocity ◽  
The Mean

Efficient actuation of liquid slugs in microfluidic circuits is a matter of interest in droplet-based microfluidic (DMF) applications. In this paper, the electrowetting on dielectric (EWOD) actuation of a liquid slug fully confined in a microchannel is studied. A set of experiments are conducted in which the mean transport velocity of a liquid slug enclosed in a microchannel of rectangular cross section and actuated by EWOD method is measured. A printed circuit board-based (PCB-based) microfluidic chip is used as the platform, and the transport velocity of the slug is measured by processing the images recorded by a high-speed camera while the slug moves in the channel. To investigate the effect of microchannel geometry on the mean transport velocity of the slugs, different channel heights and widths (ranging between 250−440μm and 1–2 mm, respectively) as well as different liquid volumes (ranging between 2.94and5.15μL) are tested and slug velocities up to 14.9 mm/s are achieved. A theoretical model is also developed to analyze the effect of involved parameters on the transport velocity. The results show that, within the range of design parameters considered in this study, for a constant slug volume and channel width, increasing the channel height enhances the velocity. Moreover, keeping the slug volume and channel height fixed, the transport velocity is increased by enlarging the channel width. An inverse proportionality between the slug length and velocity is also observed. These results are also shown to agree with the theoretical model developed.

scholarly journals Unsteady Gust Response of Road Vehicles

2003 ◽  
Vol 125 (5) ◽  
pp. 806-812 ◽  
Author(s):  
Antonio Filippone
Keyword(s):  
Theoretical Model ◽  
Frequency Domain ◽  
High Speed ◽  
Wave Length ◽  
Two Dimensional ◽  
Road Vehicles ◽  
Side Force ◽  
High Speed Trains ◽  
The Mean ◽  
Gust Response

A theoretical model based on an indicial method is proposed to simulate the unsteady response of a series of road vehicles, including high-speed trains, sports utility vehicles, sports cars, caravans, and pick-up trucks. The response is described in the frequency domain by the aerodynamic admittance for both side force and yawing moment. The properties of the admittance function are discussed for basic two-dimensional geometries, and the existence of critical damping is shown for a number of cases. The vehicles are undergoing aerodynamic forcing in the form of a gust. Systems with one degree-of-freedom were considered. The results show that the main parameters affecting the vehicle’s aerodynamic response are the mean vehicle length compared to the wave length of the gust, and the inclination of the nose.

Electrowetting on Dielectric Based Droplet Transport Inside a Closed-Channel

2010 ◽  
Author(s):  
Mohammed Jalal Ahamed ◽  
Ridha Ben-Mrad ◽  
Pierre Sullivan
Keyword(s):  
Constant Velocity ◽  
Actuation Voltage ◽  
Design Parameters ◽  
Channel Height ◽  
Closed Channel ◽  
Droplet Motion ◽  
Electrowetting On Dielectric ◽  
Droplet Transport ◽  
Open Plane ◽  
Peak Value

The paper reports Electrowetting on Dielectric (EWOD) actuated droplet transport characteristics inside a closed-channel. Traditional EWOD devices are open-plane wall-less devices within which droplets are either sitting on a substrate or sandwiched between top and bottom substrates. We investigated droplet motion by EWOD actuation inside a sealed closed-channel. Closed-channel EWOD actuation is useful for interfacing open-plane EWOD (digital) designs to closed continuous (analog) microfluidic devices. Some transport characteristics of the closed-channel EWOD actuation were investigated. Actuation voltage was varied between 85–120 VRMS. Channel height was varied between 90–150 μm. The electrodes were square shaped and 2 mm across. Within these range of design parameters the droplet velocity profile showed no steady state constant velocity. And it accelerated to the peak value near the midpoint of the energized electrode then decelerated for the rest of the travel.

Electrokinetic Flow Dynamics of Weakly Aggregated λDNA Confined in Nanochannels

2011 ◽  
Vol 133 (12) ◽  
Author(s):  
Satoshi Uehara ◽  
Hirofumi Shintaku ◽  
Satoyuki Kawano
Keyword(s):  
Theoretical Model ◽  
Electric Field ◽  
High Speed ◽  
Terminal Velocity ◽  
Flow Dynamics ◽  
Radius Of Gyration ◽  
Channel Height ◽  
Next Generation ◽  
Electrokinetic Flow ◽  
Design Data

Flow dynamics in nano-scaled structures such as nanochannels and nanopores have recently become important in developing next-generation high-speed DNA sequencers. In the present paper, we report the electrokinetic flow dynamics of λDNA confined in nanochannels having heights that are smaller than the molecular radius of gyration. Nanochannels of varying heights of from 330 to 650 nm were used in the experiments in order to systematically investigate the effect of confinement. Weakly aggregated λDNA flowed in a direction opposite to an applied electric field as a result of the competition of electrophoresis and electroosmotic flows. The terminal velocity of λDNA was proportional to the strength of the electric field, and the mobility was found to decrease with the channel height. A simple theoretical model explaining the decrease in the mobility was developed taking into account the shear stress due to small clearances between λDNA and the walls of nanochannels. The validity of the model was confirmed by reasonable agreement between the theoretical and experimental results. The theoretical model and the transport properties under confinement provide basic design data for the development of next-generation DNA sequencers.

Articulatory Behavior Pre and Post Full-Mouth Tooth Extraction and Alveoloplasty

1980 ◽  
Vol 23 (3) ◽  
pp. 630-645 ◽  
Author(s):  
Gerald Zimmermann ◽  
J.A. Scott Kelso ◽  
Larry Lander
Keyword(s):  
Control Subject ◽  
High Speed ◽  
Tooth Extraction ◽  
Kinematic Parameters ◽  
Experimental Conditions ◽  
Mean Values ◽  
Articulatory Movements ◽  
The Mean ◽  
Experimental Subjects ◽  
Normal Speech

High speed cinefluorography was used to track articulatory movements preceding and following full-mouth tooth extraction and alveoloplasty in two subjects. Films also were made of a control subject on two separate days. The purpose of the study was to determine the effects of dramatically altering the structural dimensions of the oral cavity on the kinematic parameters of speech. The results showed that the experimental subjects performed differently pre and postoperatively though the changes were in different directions for the two subjects. Differences in both means and variabilities of kinematic parameters were larger between days for the experimental (operated) subjects than for the control subject. The results for the Control subject also showed significant differences in the mean values of kinematic variables between days though these day-to-day differences could not account for the effects found pre- and postoperatively. The results of the kinematic analysis, particularly the finding that transition time was most stable over the experimental conditions for the operated subjects, are used to speculate about the coordination of normal speech.

scholarly journals The influence of solar wind on extratropical cyclones – Part 1: Wilcox effect revisited

2009 ◽  
Vol 27 (1) ◽  
pp. 1-30 ◽  
Author(s):  
P. Prikryl ◽  
V. Rušin ◽  
M. Rybanský
Keyword(s):  
Time Series ◽  
Solar Wind ◽  
Northern Hemisphere ◽  
High Speed ◽  
Coronal Holes ◽  
Extratropical Cyclones ◽  
Sector Boundary ◽  
Speed Solar Wind ◽  
The Mean ◽  
High Speed Solar Wind

Abstract. A sun-weather correlation, namely the link between solar magnetic sector boundary passage (SBP) by the Earth and upper-level tropospheric vorticity area index (VAI), that was found by Wilcox et al. (1974) and shown to be statistically significant by Hines and Halevy (1977) is revisited. A minimum in the VAI one day after SBP followed by an increase a few days later was observed. Using the ECMWF ERA-40 re-analysis dataset for the original period from 1963 to 1973 and extending it to 2002, we have verified what has become known as the "Wilcox effect" for the Northern as well as the Southern Hemisphere winters. The effect persists through years of high and low volcanic aerosol loading except for the Northern Hemisphere at 500 mb, when the VAI minimum is weak during the low aerosol years after 1973, particularly for sector boundaries associated with south-to-north reversals of the interplanetary magnetic field (IMF) BZ component. The "disappearance" of the Wilcox effect was found previously by Tinsley et al. (1994) who suggested that enhanced stratospheric volcanic aerosols and changes in air-earth current density are necessary conditions for the effect. The present results indicate that the Wilcox effect does not require high aerosol loading to be detected. The results are corroborated by a correlation with coronal holes where the fast solar wind originates. Ground-based measurements of the green coronal emission line (Fe XIV, 530.3 nm) are used in the superposed epoch analysis keyed by the times of sector boundary passage to show a one-to-one correspondence between the mean VAI variations and coronal holes. The VAI is modulated by high-speed solar wind streams with a delay of 1–2 days. The Fourier spectra of VAI time series show peaks at periods similar to those found in the solar corona and solar wind time series. In the modulation of VAI by solar wind the IMF BZ seems to control the phase of the Wilcox effect and the depth of the VAI minimum. The mean VAI response to SBP associated with the north-to-south reversal of BZ is leading by up to 2 days the mean VAI response to SBP associated with the south-to-north reversal of BZ. For the latter, less geoeffective events, the VAI minimum deepens (with the above exception of the Northern Hemisphere low-aerosol 500-mb VAI) and the VAI maximum is delayed. The phase shift between the mean VAI responses obtained for these two subsets of SBP events may explain the reduced amplitude of the overall Wilcox effect. In a companion paper, Prikryl et al. (2009) propose a new mechanism to explain the Wilcox effect, namely that solar-wind-generated auroral atmospheric gravity waves (AGWs) influence the growth of extratropical cyclones. It is also observed that severe extratropical storms, explosive cyclogenesis and significant sea level pressure deepenings of extratropical storms tend to occur within a few days of the arrival of high-speed solar wind. These observations are discussed in the context of the proposed AGW mechanism as well as the previously suggested atmospheric electrical current (AEC) model (Tinsley et al., 1994), which requires the presence of stratospheric aerosols for a significant (Wilcox) effect.

scholarly journals Modeling the Excess Velocity of Low-Viscous Taylor Droplets in Square Microchannels

Fluids ◽  
2019 ◽  
Vol 4 (3) ◽  
pp. 162 ◽  
Author(s):  
Thorben Helmers ◽  
Philip Kemper ◽  
Jorg Thöming ◽  
Ulrich Mießner
Keyword(s):  
High Speed ◽  
Process Intensification ◽  
Continuous Phase ◽  
Channel Cross Section ◽  
Optimization Approach ◽  
Mean Flow ◽  
Bypass Flow ◽  
Wall Film ◽  
Proposed Model ◽  
The Mean

Microscopic multiphase flows have gained broad interest due to their capability to transfer processes into new operational windows and achieving significant process intensification. However, the hydrodynamic behavior of Taylor droplets is not yet entirely understood. In this work, we introduce a model to determine the excess velocity of Taylor droplets in square microchannels. This velocity difference between the droplet and the total superficial velocity of the flow has a direct influence on the droplet residence time and is linked to the pressure drop. Since the droplet does not occupy the entire channel cross-section, it enables the continuous phase to bypass the droplet through the corners. A consideration of the continuity equation generally relates the excess velocity to the mean flow velocity. We base the quantification of the bypass flow on a correlation for the droplet cap deformation from its static shape. The cap deformation reveals the forces of the flowing liquids exerted onto the interface and allows estimating the local driving pressure gradient for the bypass flow. The characterizing parameters are identified as the bypass length, the wall film thickness, the viscosity ratio between both phases and the C a number. The proposed model is adapted with a stochastic, metaheuristic optimization approach based on genetic algorithms. In addition, our model was successfully verified with high-speed camera measurements and published empirical data.

scholarly journals Formulation and in vitro evaluation of self-nanoemulsifying liquisolid tablets of furosemide

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lena Dalal ◽  
Abdul Wahab Allaf ◽  
Hind El-Zein
Keyword(s):  
Theoretical Model ◽  
Castor Oil ◽  
In Vivo Studies ◽  
Coating Materials ◽  
Peg 400 ◽  
The Mean ◽  
Usp Apparatus ◽  
Solid System

AbstractSelf-nanoemulsifying drug delivery systems (SNEDDS) were used to enhance the dissolution rate of furosemide as a model for class IV drugs and the system was solidified into liquisolid tablets. SNEDDS of furosemide contained 10% Castor oil, 60% Cremophor EL, and 30% PEG 400. The mean droplets size was 17.9 ± 4.5 nm. The theoretical model was used to calculate the amounts of the carrier (Avicel PH101) and coating materials (Aerosil 200) to prepare liquisolid powder. Carrier/coating materials ratio of 5/1 was used and Ludipress was added to the solid system, thus tablets with hardness of 45 ± 2 N were obtained. Liquisolid tablets showed 2-folds increase in drug release as compared to the generic tablets after 60 min in HCl 0.1 N using USP apparatus-II. Furosemide loaded SNEDDS tablets have great prospects for further in vivo studies, and the theoretical model is useful for calculating the adequate amounts of adsorbents required to solidify these systems.

Aerodynamic and aeroacoustic performance investigations on modified H-rotor Darrieus wind turbine

2021 ◽  
pp. 0309524X2110039
Author(s):  
Amgad Dessoky ◽  
Thorsten Lutz ◽  
Ewald Krämer
Keyword(s):  
Wind Turbine ◽  
High Speed ◽  
Cfd Simulation ◽  
Vertical Axis ◽  
3D Models ◽  
Power Coefficient ◽  
Design Parameters ◽  
Second Phase ◽  
Vertical Axis Wind Turbine ◽  
Guide Vanes

The present paper investigates the aerodynamic and aeroacoustic characteristics of the H-rotor Darrieus vertical axis wind turbine (VAWT) combined with very promising energy conversion and steering technology; a fixed guide-vanes. The main scope of the current work is to enhance the aerodynamic performance and assess the noise production accomplished with such enhancement. The studies are carried out in two phases; the first phase is a parametric 2D CFD simulation employing the unsteady Reynolds-averaged Navier-Stokes (URANS) approach to optimize the design parameters of the guide-vanes. The second phase is a 3D CFD simulation of the full turbine using a higher-order numerical scheme and a hybrid RANS/LES (DDES) method. The guide-vanes show a superior power augmentation, about 42% increase in the power coefficient at λ = 2.75, with a slightly noisy operation and completely change the signal directivity. A remarkable difference in power coefficient is observed between 2D and 3D models at the high-speed ratios stems from the 3D effect. As a result, a 3D simulation of the capped Darrieus turbine is carried out, and then a noise assessment of such configuration is assessed. The results show a 20% increase in power coefficient by using the cap, without significant change in the noise signal.

scholarly journals Clogging sensitivity of flow distributors designed for radially elongated hexagonal pillar array columns: a computational modelling

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Farideh Haghighi ◽  
Zahra Talebpour ◽  
Amir Sanati-Nezhad
Keyword(s):  
Pressure Drop ◽  
Aspect Ratio ◽  
Contact Zone ◽  
Separation Efficiency ◽  
Fluid Dynamic ◽  
Computational Modelling ◽  
Channel Width ◽  
Fluid Distribution ◽  
Design Parameters ◽  
Pillar Array

AbstractFlow distributor located at the beginning of the micromachined pillar array column (PAC) has significant roles in uniform distribution of flow through separation channels and thus separation efficiency. Chip manufacturing artifacts, contaminated solvents, and complex matrix of samples may contribute to clogging of the microfabricated channels, affect the distribution of the sample, and alter the performance of both natural and engineered systems. An even fluid distribution must be achieved cross-sectionally through careful design of flow distributors and minimizing the sensitivity to clogging in order to reach satisfactory separation efficiency. Given the difficulty to investigate experimentally a high number of clogging conditions and geometries, this work exploits a computational fluid dynamic model to investigate the effect of various design parameters on the performance of flow distributors in equally spreading the flow along the separation channels in the presence of different degrees of clogging. An array of radially elongated hexagonal pillars was selected for the separation channel (column). The design parameters include channel width, distributor width, aspect ratio of the pillars, and number of contact zone rows. The performance of known flow distributors, including bifurcating (BF), radially interconnected (RI), and recently introduced mixed-mode (MMI) in addition to two new distributors designed in this work (MMII and MMIII) were investigated in terms of mean elution time, volumetric variance, asymmetry factors, and pressure drop between the inlet and the monitor line for each design. The results show that except for pressure drop, the channel width and aspect ratio of the pillars has no significant influence on flow distribution pattern in non-clogged distributors. However, the behavior of flow distributors in response to clogging was found to be dependent on width of the channels. Also increasing the distributor width and number of contact zone rows after the first splitting stage showed no improvement in the ability to alleviate the clogging. MMI distributor with the channel width of 3 µm, aspect ratio of the pillars equal to 20, number of exits of 8, and number of contact zones of 3 exhibited the highest stability and minimum sensitivity to different degrees of clogging.

The Engagement of Hybrid Ultra High Space Division Multiplexing with Maximum Time Division Multiplexing Techniques for High-Speed Single-Mode Fiber Cable Systems

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
I. S. Amiri ◽  
P. G. Kuppusamy ◽  
Ahmed Nabih Zaki Rashed ◽  
P. Jayarajan ◽  
M. R. Thiyagupriyadharsan ◽  
...  
Keyword(s):  
Communication Systems ◽  
High Speed ◽  
Single Mode ◽  
Single Mode Fiber ◽  
Design Parameters ◽  
Control Parameters ◽  
Data Rates ◽  
Fiber Optic Communication ◽  
High Space ◽  
Optic Communication

AbstractHigh-speed single-mode fiber-optic communication systems have been presented based on various hybrid multiplexing schemes. Refractive index step and silica-doped germanium percentage parameters are also preserved during their technological boundaries of attention. It is noticed that the connect design parameters suffer more nonlinearity with the number of connects. Two different propagation techniques have been used to investigate the transmitted data rates as a criterion to enhance system performance. The first technique is soliton propagation, where the control parameters lead to equilibrium between the pulse spreading due to dispersion and the pulse shrinking because of nonlinearity. The second technique is the MTDM technique where the parameters are adjusted to lead to minimum dispersion. Two cases are investigated: no dispersion cancellation and dispersion cancellation. The investigations are conducted over an enormous range of the set of control parameters. Thermal effects are considered through three basic quantities, namely the transmission data rates, the dispersion characteristics, and the spectral losses.

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