scholarly journals Responses of glutamine transport in cultured rat skeletal muscle to osmotically induced changes in cell volume.

1996 ◽  
Vol 492 (3) ◽  
pp. 877-885 ◽  
Author(s):  
S Y Low ◽  
P M Taylor ◽  
M J Rennie
Keyword(s):  
Skeletal Muscle ◽  
Cell Volume ◽  
Rat Skeletal Muscle ◽  
Glutamine Transport ◽  
Induced Changes

Ischemia/reperfusion-induced changes in intracellular free Ca2+ levels in rat skeletal muscle fibers – an in vivo study

2000 ◽  
Vol 440 (2) ◽  
pp. 302-308 ◽  
Author(s):  
Tamás Ivanics ◽  
Zsuzsa Miklós ◽  
Zoltán Ruttner ◽  
Sándor Bátkai ◽  
Dick W. Slaaf ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Ischemia Reperfusion ◽  
Muscle Fibers ◽  
In Vivo Study ◽  
Rat Skeletal Muscle ◽  
Skeletal Muscle Fibers ◽  
Induced Changes

Contraction-induced changes in TNFα and Akt-mediated signalling are associated with increased myofibrillar protein in rat skeletal muscle

2010 ◽  
Vol 109 (5) ◽  
pp. 839-848 ◽  
Author(s):  
Leonidas G. Karagounis ◽  
Ben B. Yaspelkis ◽  
Donald W. Reeder ◽  
Graeme I. Lancaster ◽  
John A. Hawley ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Myofibrillar Protein ◽  
Rat Skeletal Muscle ◽  
Induced Changes

Glutamine transport and metabolism in denervated rat skeletal muscle

1990 ◽  
Vol 259 (2) ◽  
pp. E148-E154 ◽  
Author(s):  
H. S. Hundal ◽  
P. Babij ◽  
P. W. Watt ◽  
M. R. Ward ◽  
M. J. Rennie
Keyword(s):  
Skeletal Muscle ◽  
Membrane Potential ◽  
Maximal Activity ◽  
Resting Membrane Potential ◽  
Na Channel ◽  
Synthetase Activity ◽  
Glutamine Synthetase Activity ◽  
Rat Skeletal Muscle ◽  
Glutamine Transport ◽  
Recovery Of Vmax

Rat skeletal muscle glutamine fell by 40% from 4.18 to 2.5 mumols/g wet weight (P less than 0.01) after 4 days of denervation. Over the same period net glutamine efflux from denervated hindlimbs [i.e., arteriovenous (a-v) concentration differences x blood flow] increased 3.5-fold (from -6.72 +/- 1.73 to -26 +/- 4.81 nmol.min-1.g-1, P less than 0.001). Gastrocnemius glutamine synthetase activity fell 48% after denervation (from 475 +/- 81 to 248 +/- 39 nmol.min-1.g-1, P less than 0.001), but glutaminase activity was not significantly altered (17 nmol.min-1.g-1). The maximal activity (Vmax) of the unidirectional Na(+)-dependent glutamine transporter (system Nm) was depressed by 45% from 1,020 +/- 104 to 571 +/- 9 nmol.min-1.g-1 (P less than 0.01), but the concentration at which transport was half maximal (Km) was not significantly altered (control 8.1 +/- 0.6 mM; denervated 6.52 +/- 0.12). Hindlimb denervation resulted in an increase of intramuscular Na+ by 17% and a fall of K+ by 12%, and the resting membrane potential in isolated muscles decreased from -75 +/- 10 to -59.5 +/- 5.5 mV. Membrane potential of perfused denervated muscle, isolated after acute addition of the Na+ channel blocker tetrodotoxin (TTX, 3 microM), repolarized to -66.4 +/- 3.2 mV. In perfused denervated preparations TTX caused an acute recovery of Vmax of unidirectional glutamine transport to 848 +/- 75 nmol.min-1.g-1; Km was unaffected.(ABSTRACT TRUNCATED AT 250 WORDS)

ATP-induced changes in rat skeletal muscle contractility

2015 ◽  
Vol 27 (s1) ◽  
pp. S82-S83 ◽  
Author(s):  
A.I. Gabdrakhmanov ◽  
A.E. Khayrullin ◽  
C.H. Grishin ◽  
A.U. Ziganshin
Keyword(s):  
Skeletal Muscle ◽  
Rat Skeletal Muscle ◽  
Muscle Contractility ◽  
Induced Changes

THE EFFECT OF CELL VOLUME ON THE RATE OF LACTATE RELEASE FROM RAT SKELETAL MUSCLE

1991 ◽  
Vol 19 (2) ◽  
pp. 198S-198S ◽  
Author(s):  
S.J. Bevan ◽  
M. Parry-Billings ◽  
E. Opara ◽  
E.A. Newsholme
Keyword(s):  
Skeletal Muscle ◽  
Cell Volume ◽  
Rat Skeletal Muscle ◽  
Lactate Release
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