scholarly journals A simplified method for the determination of circulating red‐cell volume with radioactive phosphorus

1949 ◽  
Vol 108 (1) ◽  
pp. 12-23 ◽  
Author(s):  
E. B. Reeve ◽  
N. Veall
1997 ◽  
Vol 24 (3) ◽  
pp. 132-137
Author(s):  
M. Haller ◽  
H. Dressel ◽  
M. Thiel ◽  
V. Orth ◽  
H. Brechtelsbauer ◽  
...  

1960 ◽  
Vol 198 (1) ◽  
pp. 183-186 ◽  
Author(s):  
S. M. Weissman ◽  
T. A. Waldmann ◽  
N. I. Berlin

The quantitative measurement of erythropoiesis requires the simultaneous determination of total red cell volume, rate of production of red cells and the red cell life span. The total red cell volume was measured with autologous Cr51-labeled red cells, the rate of production of red cells from the rate of disappearance of radioiron from the plasma and uptake by red cells, the red cell life span with C14-labeled glycine and the apparent red cell survival T1/2 with Cr51. The average total red cell volume of the dogs studied was 38.6 cc/kg; the plasma radioiron T1/2 was 66 minutes; the red cell radio-iron uptake was 80%; the serum iron was 102 µg/100 cc, and the plasma volume calculated from the peripheral hematocrit and total red cell volume was 46 cc/kg, and from the extrapolation to t0 of the radioiron disappearance was 48 cc/kg. From these figures the plasma iron turnover was calculated to be 0.63 mg/kg/day and the red cell iron renewal rate 1.26%/day. The average red cell life span was 108 days; the average apparent T1/2 of Cr51 red cell survival was 24.3 days; the average elution rate of Cr51 was 1.77%/day.


1962 ◽  
Vol 14 (4) ◽  
pp. 355-367 ◽  
Author(s):  
R. Wennesland ◽  
E. Brown ◽  
J. Hopper ◽  
K. G. Scott ◽  
J. L. Hodges ◽  
...  
Keyword(s):  
Red Cell ◽  

1958 ◽  
Vol 195 (3) ◽  
pp. 628-630 ◽  
Author(s):  
L. Kraintz ◽  
J. de Boer ◽  
E. L. Smith ◽  
R. A. Huggins

Dogs anesthetized with morphine-pentobarbital were injected with Cr51-tagged red cells, and their mixing time in the general circulation and the spleen was compared. The necessary blood samples were taken and the spleens rapidly excised at 10, 20 or 30 minutes after the injection of the tagged red cells. When the data were grouped according to the size of the spleen and irrespective of the time of removal, the mixing of tagged red cells in small spleens was practically the same as in the general circulation. With increasing sizes of spleens the mixing appeared to be progressively less complete than in the general circulation. If the spleen size was disregarded and the data grouped according to the time after the injections of tagged red cells mixing in the spleen was still incomplete after 30 minutes. However, the maximum mean possible error that could be introduced into the determination of total red cell volume if all the unmixed red cells were ejected into the general circulation would be less than 5% at the 20-minute period.


2000 ◽  
Vol 10 (3) ◽  
pp. 219-224 ◽  
Author(s):  
Fisher ◽  
Matthes ◽  
Wynn ◽  
Al-Ismail ◽  
Hoy ◽  
...  

1959 ◽  
Vol 196 (4) ◽  
pp. 703-705 ◽  
Author(s):  
E. J. Fedor ◽  
B. Fisher

Dogs lightly anesthetized with ether, maintained between 23–24°C for 2 hours and rewarmed, were subjected to simultaneous determinations of red cell volume (Cr51) and plasma volume (T-1824). Red cell volume values were unchanged during the course of the experiment. Plasma volumes were significantly decreased during hypothermia and were transiently elevated during rewarming. Twenty-four hours after rewarming, total blood volume and plasma volume values were not significantly different from control values. It would seem that circulatory failure (‘rewarming shock’) is not a usual feature of rewarming following hypothermia of 2 hours duration.


1959 ◽  
Vol 101 (2) ◽  
pp. 233-235 ◽  
Author(s):  
M. D. Pareira ◽  
K. D. Serkes ◽  
S. Lang

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