scholarly journals Global REACH 2018: Andean highlanders, chronic mountain sickness and the integrative regulation of resting blood pressure

2020 ◽  
Vol 106 (1) ◽  
pp. 104-116 ◽  
Author(s):  
Lydia L. Simpson ◽  
Victoria L. Meah ◽  
Andrew R. Steele ◽  
Christopher Gasho ◽  
Connor A. Howe ◽  
...  
2021 ◽  
Author(s):  
Alexander B. Hansen ◽  
Gilbert Moralez ◽  
Sachin B. Amin ◽  
Lydia L. Simspon ◽  
Florian Hofstaetter ◽  
...  

Hypertension ◽  
2020 ◽  
Vol 76 (6) ◽  
pp. 1962-1970
Author(s):  
Grzegorz Bilo ◽  
Lorenzo Acone ◽  
Cecilia Anza-Ramírez ◽  
José Luis Macarlupú ◽  
Davide Soranna ◽  
...  

Millions of people worldwide live at high altitude, being chronically exposed to hypobaric hypoxia. Hypertension is a major cardiovascular risk factor but data on its prevalence and determinants in highlanders are limited, and systematic studies with ambulatory blood pressure monitoring are not available. Aim of this study was to assess the prevalence of clinic and ambulatory hypertension and the associated factors in a sample of Andean highlanders. Hypertension prevalence and phenotypes were assessed with office and ambulatory blood pressure measurement in a sample of adults living in Cerro de Pasco, Peru (altitude 4340 m). Basic clinical data, blood oxygen saturation, hematocrit, and Qinghai Chronic Mountain Sickness score were obtained. Participants were classified according to the presence of excessive erythrocytosis and chronic mountain sickness diagnosis. Data of 289 participants (143 women, 146 men, mean age 38.3 years) were analyzed. Office hypertension was present in 20 (7%) participants, while ambulatory hypertension was found in 58 (20%) participants. Masked hypertension was common (15%), and white coat hypertension was rare (2%). Among participants with ambulatory hypertension, the most prevalent phenotypes included isolated nocturnal hypertension, isolated diastolic hypertension, and systodiastolic hypertension. Ambulatory hypertension was associated with male gender, age, overweight/obesity, 24-hour heart rate, and excessive erythrocytosis. Prevalence of hypertension among Andean highlanders may be significantly underestimated when based on conventional blood pressure measurements, due to the high prevalence of masked hypertension. In highlanders, ambulatory hypertension may be independently associated with excessive erythrocytosis.


2010 ◽  
Author(s):  
Suzanne G. Helfer ◽  
Ashley D. Bugeja ◽  
Sarah E. Jackson ◽  
Elizabeth Woltja

2011 ◽  
Vol 29 (3) ◽  
pp. 303-321 ◽  
Author(s):  
Dina Eliezer ◽  
Sarah S. M. Townsend ◽  
Pamela J. Sawyer ◽  
Brenda Major ◽  
Wendy Berry Mendes

1996 ◽  
Vol 40 (4) ◽  
pp. 359-368 ◽  
Author(s):  
John Spicer ◽  
Kerry Chamberlain

Hypertension ◽  
2002 ◽  
Vol 39 (6) ◽  
pp. 1037-1043 ◽  
Author(s):  
Treva Rice ◽  
Tuomo Rankinen ◽  
Yvon C. Chagnon ◽  
Michael A. Province ◽  
Louis Pérusse ◽  
...  

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