Analysis of factors affecting return of first‐time blood donors in Japan ‐ The role of small volume whole blood collection

2021 ◽  
Author(s):  
Takeshi Odajima ◽  
Minoko Takanashi ◽  
Hiroki Sugimori ◽  
Junichi Sato ◽  
Chiharu Kano ◽  
...  
Keyword(s):  
Whole Blood ◽  
Blood Donors ◽  
Small Volume ◽  
Blood Collection ◽  
Factors Affecting ◽  
First Time

Fear is associated with attrition of first‐time whole blood donors: A longitudinal examination of donor confidence and attitude as potential mediators

Transfusion ◽  
2021 ◽  
Author(s):  
Christopher R. France ◽  
Janis L. France ◽  
Lina K. Himawan ◽  
Louisa Duffy ◽  
Debra A. Kessler ◽  
...  
Keyword(s):  
Whole Blood ◽  
Blood Donors ◽  
First Time ◽  
Longitudinal Examination

scholarly journals Skin Electrical Resistance Measurement of Oxygen-Containing Terpenes as Penetration Enhancers: Role of Stratum Corneum Lipids

Molecules ◽  
2019 ◽  
Vol 24 (3) ◽  
pp. 523 ◽  
Author(s):  
Xue-min Zhu ◽  
Yu Li ◽  
Fei Xu ◽  
Wei Gu ◽  
Guo-jun Yan ◽  
...  
Keyword(s):  
Stratum Corneum ◽  
Electrical Resistance ◽  
Attenuated Total Reflection ◽  
Penetration Enhancers ◽  
Rapid Screening ◽  
Factors Affecting ◽  
Skin Cell ◽  
First Time

The measurement of skin electrical resistance (SER) has drawn a great deal of attention for the rapid screening of transdermal penetration enhancers (PEs). However, the mechanisms underlying the SER measurement are still unclear. This study was to investigate the effects and mechanisms of seven oxygen-containing terpenes on the SER kinetics. Stratum corneum (SC) lipids were proved to play a key role in SER measurement. Then, the factors affecting the SER measurement were optimized. By the determination of SER kinetics, cyclic terpenes (1,8-cineole, terpinen-4-ol, menthol and α-terpineol) were demonstrated to possess higher enhancement ratio (ER) values compared with linear terpenes (linalool, geraniol and citral). For the first time, the linear correlation was found between ER of terpenes and the interaction energy of terpene–ceramide complexes revealed by molecular simulation. The attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR) analysis revealed that the effect of cyclic terpenes on SC lipid arrangement was obviously stronger than that of linear terpenes. In addition, by evaluating HaCaT skin cell viability, little difference was found between the toxicities of cyclic and linear terpenes. In conclusion, measurement of SER could be a feasible approach for the efficient evaluation of the PEs that mainly act on SC lipids.

Well-being and return rate of first-time whole blood donors

Vox Sanguinis ◽  
2019 ◽  
Vol 114 (2) ◽  
pp. 154-161 ◽  
Author(s):  
Peer Jansen ◽  
Ariane Sümnig ◽  
Max Esefeld ◽  
Klara Greffin ◽  
Lars Kaderali ◽  
...  
Keyword(s):  
Whole Blood ◽  
Blood Donors ◽  
Well Being ◽  
Return Rate ◽  
First Time

scholarly journals FinDonor 10 000 study: A cohort to identify iron depletion and factors affecting it in Finnish blood donors

2018 ◽  
Author(s):  
Jukka Partanen ◽  
Pia Niittymäki ◽  
Nina Nikiforow ◽  
Elina Palokangas ◽  
Muriel Lobier ◽  
...  
Keyword(s):  
Whole Blood ◽  
Blood Donors ◽  
Iron Status ◽  
Time Lag ◽  
Time Of Day ◽  
Cool Temperature ◽  
Factors Affecting ◽  
Iron Stores ◽  
Increased Risk ◽  
Donation Frequency

AbstractBackground and ObjectivesThere is increasing evidence that frequent blood donation depletes the iron stores of some blood donors. The FinDonor 10 000 study was set up to study iron status and factors affecting iron stores in Finnish blood donors. In Finland, iron supplementation for at-risk groups has been in place since the 1980’s.Material and Methods2584 blood donors (N= 8003 samples) were recruited into the study alongside the standard donation at three donation sites in the capital region of Finland between 5/2015 and 12/2017. All participants were asked to fill out a questionnaire about their health and lifestyle. Blood samples were collected from the sample pouch of whole blood collection set, kept in cool temperature and processed centrally. Whole blood count, CRP, ferritin and sTFR were measured from the samples and DNA was isolated for GWAS studies.ResultsParticipant demographics, albeit in general similar to the general blood donor population in Finland, indicated some bias toward older and more frequent donors. Participation in the study increased median donation frequency of the donors. Analysis of the effect of time lag from the sampling to the analysis and the time of day when sample was drawn revealed small but significant time-dependent changes.ConclusionThe FinDonor cohort now provides us with tools to identify potential donor groups at increased risk of iron deficiency as factors explaining this risk. The increase in donation frequency during the study suggests that scientific projects can be used to increase the commitment of blood donors.

scholarly journals Novel Insight Into the Development and Function of Hypopharyngeal Glands in Honey Bees

2021 ◽  
Vol 11 ◽  
Author(s):  
Saboor Ahmad ◽  
Shahmshad Ahmed Khan ◽  
Khalid Ali Khan ◽  
Jianke Li
Keyword(s):  
Honey Bees ◽  
Future Research ◽  
Factors Affecting ◽  
Hypopharyngeal Glands ◽  
And Function ◽  
First Time ◽  
The Brain ◽  
Insight Into ◽  
Made In

Hypopharyngeal glands (HGs) are the most important organ of hymenopterans which play critical roles for the insect physiology. In honey bees, HGs are paired structures located bilaterally in the head, in front of the brain between compound eyes. Each gland is composed of thousands of secretory units connecting to secretory duct in worker bees. To better understand the recent progress made in understanding the structure and function of these glands, we here review the ontogeny of HGs, and the factors affecting the morphology, physiology, and molecular basis of the functionality of the glands. We also review the morphogenesis of HGs in the pupal and adult stages, and the secretory role of the glands across the ages for the first time. Furthermore, recent transcriptome, proteome, and phosphoproteome analyses have elucidated the potential mechanisms driving the HGs development and functionality. This adds a comprehensive novel knowledge of the development and physiology of HGs in honey bees over time, which may be helpful for future research investigations.

Role of salt supplementation on vasovagal reactions in young whole blood donors

2019 ◽  
Vol 15 (2) ◽  
pp. 253-260
Author(s):  
Karan Kumar ◽  
Suchet Sachdev ◽  
Neelam Marwaha ◽  
Ratti Ram Sharma
Keyword(s):  
Whole Blood ◽  
Blood Donors ◽  
Vasovagal Reactions

scholarly journals Change in haematological and selected biochemical parameters measured in feline blood donors and feline whole blood donated units

2016 ◽  
Vol 19 (4) ◽  
pp. 375-381 ◽  
Author(s):  
Eva Spada ◽  
Daniela Proverbio ◽  
Luciana Baggiani ◽  
Giada Bagnagatti De Giorgi ◽  
Elisabetta Ferro ◽  
...  
Keyword(s):  
Blood Donor ◽  
Whole Blood ◽  
Blood Cells ◽  
Biochemical Parameters ◽  
Blood Donors ◽  
White Blood Cells ◽  
Mean Difference ◽  
Blood Collection ◽  
Distribution Width ◽  
Selection Of

Objectives The quality of whole blood (WB) units is influenced by many factors, starting with selection of donors and the method of blood collection. The aim of this study was to investigate the changes that occur in haematological and selected biochemical parameters in blood transferred from a feline blood donor to feline WB unit. Methods Data from 27 feline blood donations were used in this study. Cats were anaesthetised with a combination of tiletamine and zolazepam. Blood (10 ml/kg body weight to a maximum of 60 ml/cat) was collected in citrate–phosphate–dextrose–adenine (CPDA) anticoagulant. Lactated Ringer’s solution (10 ml/kg) was administered intravenously starting halfway through the donation. Haematological and selected biochemical parameters (complete blood count, free haemoglobin, % haemolysis, glucose, sodium, potassium, pH) were measured in the blood donor before donation and in the corresponding donated WB unit soon after collection. Results Significant decreases occurred between blood donor and WB unit in red blood cells (mean difference −1.06 × 1012/l; P <0.0001), haemoglobin (mean difference −1.6 g/dl; P <0.0001), haematocrit (mean difference −4.6%; P <0.0001), red cell distribution width (mean difference −0.9%; P = 0.0003), white blood cells (mean difference −2.17 × 109/l; P <0.0001), pH (mean difference −0.5; P <0.0001) and potassium (mean difference −1.4 mmol/l; P <0.0001). Significant increases occurred between blood donor and WB unit in platelets (mean difference +87.00 ×109/l; P = 0.0039), glucose (mean difference +25.42 mmol/l; P <0.0001) and sodium (mean difference +20 mmol/l; P <0.0001). Conclusions and relevance When using a blood collection protocol with intravenous fluid administration midway through the donation and a CPDA:blood ratio of 1:7, there were significant changes in both the haematological and biochemical characteristics between the blood donors and WB units. The majority of these changes may be the result of the anticoagulants used for storage. Understanding these changes may assist selection of blood donors and help prediction of the characteristics of the donated WB unit.

scholarly journals Blood Donation Fear, Perceived Rewards, Self-Efficacy, and Intention to Return Among Whole Blood Donors in China: A Social Cognitive Perspective

2021 ◽  
Vol 12 ◽  
Author(s):  
Zhong Li ◽  
Shuge Lei ◽  
Xiaoming Li ◽  
Yilun Zhao ◽  
Yudong Dai ◽  
...  
Keyword(s):  
Whole Blood ◽  
Self Efficacy ◽  
Blood Donors ◽  
Social Cognitive ◽  
Blood Donation ◽  
Blood Collection ◽  
Extrinsic Rewards ◽  
Cognitive Perspective ◽  
Intrinsic Rewards ◽  
Intention To Return

With the increasing demand from aging population and seasonal blood shortage, recruiting and retaining blood donors has become an urgent issue for the blood collection centers in China. This study aims to understand intention to donate again from a social cognitive perspective among whole blood donors in China through investigating the association between the blood donation fear, perceived rewards, self-efficacy, and intention to return. A cross-sectional survey was conducted in six cities, which are geographically and socioeconomically distinct areas in Jiangsu, China. Respondents completed a self-administrated questionnaire interviewed by two well-trained medical students. A total of 191 blood donors were included in the current study. Descriptive analysis, correlation analysis, and a generalized linear regression model were used to explore the association between demographic characteristics, psychological factors, and intention to donate again. After controlling other covariates, donors with higher fear scores reported lower intention to return (p = 0.008). Association between self-efficacy and intention to return was statistically significant (p &lt; 0.001), whereas the association between intrinsic rewards (p = 0.387), extrinsic rewards (p = 0.939), and intention to return were statistically insignificant. This study found that either intrinsic rewards or extrinsic rewards are not significantly associated with intention to donate again among whole blood donors in China, and fear is negatively associated with intention to donate again. Therefore, purposive strategies could be enacted beyond appeals to rewards and focus on the management of donors’ fear.

Motivation in Italian whole blood donors and the role of commitment

2011 ◽  
Vol 16 (6) ◽  
pp. 641-649 ◽  
Author(s):  
Marco Bani ◽  
Maria Grazia Strepparava
Keyword(s):  
Whole Blood ◽  
Blood Donors
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