The small RNA‐mediated gene silencing machinery is required in Arabidopsis for stimulation of growth, systemic disease resistance, and the suppression of nitrile‐specifier, NSP4 gene by Trichoderma atroviride

2021 ◽  
Author(s):  
Oscar Guillermo Rebolledo Prudencio ◽  
Magnolia Estrada Rivera ◽  
Mitzuko Dautt Castro ◽  
Mario A. Arteaga‐Vazquez ◽  
Catalina Arenas‐Huertero ◽  
...  
Keyword(s):  
Disease Resistance ◽  
Gene Silencing ◽  
Small Rna ◽  
Systemic Disease ◽  
Nsp4 Gene ◽  
Trichoderma Atroviride ◽  
Stimulation Of

Colonization of Arabidopsis roots by Trichoderma atroviride promotes growth and enhances systemic disease resistance through jasmonic acid/ethylene and salicylic acid pathways

2011 ◽  
Vol 131 (1) ◽  
pp. 15-26 ◽  
Author(s):  
Miguel Angel Salas-Marina ◽  
Miguel Angel Silva-Flores ◽  
Edith Elena Uresti-Rivera ◽  
Ernestina Castro-Longoria ◽  
Alfredo Herrera-Estrella ◽  
...  
Keyword(s):  
Salicylic Acid ◽  
Disease Resistance ◽  
Jasmonic Acid ◽  
Systemic Disease ◽  
Trichoderma Atroviride

scholarly journals The Epl1 and Sm1 proteins from Trichoderma atroviride and Trichoderma virens differentially modulate systemic disease resistance against different life style pathogens in Solanum lycopersicum

2015 ◽  
Vol 6 ◽  
Author(s):  
Miguel A. Salas-Marina ◽  
María I. Isordia-Jasso ◽  
María A. Islas-Osuna ◽  
Pablo Delgado-Sánchez ◽  
Juan F. Jiménez-Bremont ◽  
...  
Keyword(s):  
Disease Resistance ◽  
Solanum Lycopersicum ◽  
Life Style ◽  
Systemic Disease ◽  
Trichoderma Atroviride ◽  
Trichoderma Virens

Abstract P068: Obstructive Sleep Apnea is Associated with an Increase Risk of Osteoporosis

Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Anawin Sanguankeo ◽  
Sikarin Upala
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Primary Outcome ◽  
Meta Analysis ◽  
Systemic Disease ◽  
Obstructive Sleep ◽  
Increased Risk ◽  
Increase Risk ◽  
Osteoporosis Risk ◽  
Stimulation Of

Background: Obstructive sleep apnea (OSA) is thought to be a systemic disease and has been associated with many disorders such as metabolic, endocrine, and especially cardiovascular diseases. One of the consequences of OSA is hypoxia, which can lead to a reduction in growth of osteoblast and a stimulation of osteoclast. Our meta-analysis was conducted to determine the risk of osteoporosis in patients with OSA compared to controls. Objectives: Eligible studies assessing the effects of obstructive sleep apnea on osteoporosis risk were comprehensively searched in PubMed/MEDLINE, EMBASE, and CENTRAL from their inception to September 2014. Two authors independently assessed article quality and extracted the data. Primary outcome were number of participants, prevalence, or risk ratio of osteoporosis in OSA and controls. Results: From 40 full-text articles, 3 studies involving 113,090 participants were included in the meta-analysis that were based on the random effects model. Compared with controls, participants who were diagnosed with obstructive sleep apnea had increased risk of osteoporosis (pooled risks ratio, 1.85; 95% CI, 1.34, 2.56). Conclusion: Patients with OSA had a higher risk of developing osteoporosis. Further study is needed to evaluate the possible mechanisms between these two conditions and to find potential treatment for OSA that could prevent osteoporosis.

scholarly journals FOXO regulates RNA interference in Drosophila and protects from RNA virus infection

2015 ◽  
Vol 112 (47) ◽  
pp. 14587-14592 ◽  
Author(s):  
Michael J. Spellberg ◽  
Michael T. Marr
Keyword(s):  
Rna Interference ◽  
Virus Infection ◽  
Gene Silencing ◽  
Small Rna ◽  
Stress Responses ◽  
Posttranscriptional Regulation ◽  
Rna Virus ◽  
Regulation Of Gene Expression ◽  
Cellular Physiology ◽  
Metabolic Conditions

Small RNA pathways are important players in posttranscriptional regulation of gene expression. These pathways play important roles in all aspects of cellular physiology from development to fertility to innate immunity. However, almost nothing is known about the regulation of the central genes in these pathways. The forkhead box O (FOXO) family of transcription factors is a conserved family of DNA-binding proteins that responds to a diverse set of cellular signals. FOXOs are crucial regulators of cellular homeostasis that have a conserved role in modulating organismal aging and fitness. Here, we show that Drosophila FOXO (dFOXO) regulates the expression of core small RNA pathway genes. In addition, we find increased dFOXO activity results in an increase in RNA interference (RNAi) efficacy, establishing a direct link between cellular physiology and RNAi. Consistent with these findings, dFOXO activity is stimulated by viral infection and is required for effective innate immune response to RNA virus infection. Our study reveals an unanticipated connection among dFOXO, stress responses, and the efficacy of small RNA-mediated gene silencing and suggests that organisms can tune their gene silencing in response to environmental and metabolic conditions.

Small RNAs in Plant Immunity and Virulence of Filamentous Pathogens

2021 ◽  
Vol 59 (1) ◽  
Author(s):  
Yongli Qiao ◽  
Rui Xia ◽  
Jixian Zhai ◽  
Yingnan Hou ◽  
Li Feng ◽  
...  
Keyword(s):  
Gene Silencing ◽  
Small Rna ◽  
Small Rnas ◽  
Plant Immunity ◽  
Receptor Gene ◽  
Current Status ◽  
Annual Review ◽  
Publication Date ◽  
Small Interfering Rnas ◽  
Host Pathogen

Gene silencing guided by small RNAs governs a broad range of cellular processes in eukaryotes. Small RNAs are important components of plant immunity because they contribute to pathogen-triggered transcription reprogramming and directly target pathogen RNAs. Recent research suggests that silencing of pathogen genes by plant small RNAs occurs not only during viral infection but also in nonviral pathogens through a process termed host-induced gene silencing, which involves trans-species small RNA trafficking. Similarly, small RNAs are also produced by eukaryotic pathogens and regulate virulence. This review summarizes the small RNA pathways in both plants and filamentous pathogens, including fungi and oomycetes, and discusses their role in host–pathogen interactions. We highlight secondary small interfering RNAs of plants as regulators of immune receptor gene expression and executors of host-induced gene silencing in invading pathogens. The current status and prospects of small RNAs trafficking at the host–pathogen interface are discussed. Expected final online publication date for the Annual Review of Phytopathology, Volume 59 is August 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Mechanisms of small RNA mediated mammalian gene silencing

2007 ◽  
Vol 21 (5) ◽  
Author(s):  
Thomas Tuschl ◽  
Pablo Landgraf ◽  
Janos Ludwig ◽  
Markus Landthaler ◽  
Chris Sander ◽  
...  
Keyword(s):  
Gene Silencing ◽  
Small Rna ◽  
Mammalian Gene
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