Evaluation of diagnostic criteria of actinic keratosis through reflectance confocal microscopy

2020 ◽  
Vol 26 (6) ◽  
pp. 883-890
Author(s):  
Amanda Mota ◽  
Juan Manuel Piñeiro‐Maceira ◽  
Carlos Barcaui
Keyword(s):  
Confocal Microscopy ◽  
Diagnostic Criteria ◽  
Actinic Keratosis ◽  
Reflectance Confocal Microscopy

scholarly journals In Vivo Reflectance Confocal Microscopy-Diagnostic Criteria for Actinic Cheilitis and Squamous Cell Carcinoma of the Lip

2020 ◽  
Vol 9 (6) ◽  
pp. 1987
Author(s):  
Mihai Lupu ◽  
Ana Caruntu ◽  
Daniel Boda ◽  
Constantin Caruntu
Keyword(s):  
Squamous Cell Carcinoma ◽  
Confocal Microscopy ◽  
Blood Vessel ◽  
Cell Carcinoma ◽  
Diagnostic Criteria ◽  
Squamous Cell ◽  
Reflectance Confocal Microscopy ◽  
Target Cells ◽  
Actinic Cheilitis

Actinic cheilitis (AC) is one of the most frequent pathologies to affect the lips. Studies show that the most commonplace oral malignancy, squamous cell carcinoma (SCC), often emerges from AC lesions. Invasive diagnostic techniques performed on the lips carry a high risk of complications, but reflectance confocal microscopy (RCM), a non-invasive skin imaging technique, may change the current diagnostic pathway. This retrospective study was aimed at consolidating the RCM diagnostic criteria for AC and lip SCC. The study was conducted in two tertiary care centers in Bucharest, Romania. We included adults with histopathologically confirmed AC and SCC who also underwent RCM examination. Of the twelve lesions included in the study, four were AC and eight were SCC. An atypical honeycomb pattern and the presence of target cells in the epidermis were RCM features associated with AC. SCC was typified by the presence of complete disruption of the epidermal architecture and dermal inflammatory infiltrates. The mean blood vessel diameter in SCC was 18.55 µm larger than that in AC (p = 0.006) and there was no significant difference (p = 0.64) in blood vessel density, as measured by RCM, between SCC and AC. These data confirm that RCM can be useful for the in vivo distinction between AC and lip SCC.

scholarly journals Dermoscopy and Reflectance Confocal Microscopy for Monitoring the Treatment of Actinic Keratosis with Ingenol Mebutate Gel: Report of Two Cases

2016 ◽  
Vol 6 (1) ◽  
pp. 81-87 ◽  
Author(s):  
Caterina Longo ◽  
Stefania Borsari ◽  
Elisa Benati ◽  
Elvira Moscarella ◽  
Roberto Alfano ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Actinic Keratosis ◽  
Reflectance Confocal Microscopy ◽  
Ingenol Mebutate

Histopathology and reflectance confocal microscopy features of photodamaged skin and actinic keratosis

2016 ◽  
Vol 30 (11) ◽  
pp. 1901-1911 ◽  
Author(s):  
J.M. Tan ◽  
D. Lambie ◽  
S. Sinnya ◽  
A. Sahebian ◽  
H.P. Soyer ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Actinic Keratosis ◽  
Reflectance Confocal Microscopy ◽  
Photodamaged Skin

Diagnostic criteria of Netherton syndrome using noninvasive reflectance confocal microscopy

2016 ◽  
Vol 14 (5) ◽  
pp. 519-521
Author(s):  
Elisa Berthold ◽  
Dieter Metze ◽  
Marta Kogut ◽  
Alexander Enk ◽  
Holger A. Haenssle
Keyword(s):  
Confocal Microscopy ◽  
Diagnostic Criteria ◽  
Reflectance Confocal Microscopy ◽  
Netherton Syndrome
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