Diagnostic criteria of Netherton syndrome using noninvasive reflectance confocal microscopy

2016 ◽  
Vol 14 (5) ◽  
pp. 519-521
Author(s):  
Elisa Berthold ◽  
Dieter Metze ◽  
Marta Kogut ◽  
Alexander Enk ◽  
Holger A. Haenssle
2020 ◽  
Vol 9 (6) ◽  
pp. 1987
Author(s):  
Mihai Lupu ◽  
Ana Caruntu ◽  
Daniel Boda ◽  
Constantin Caruntu

Actinic cheilitis (AC) is one of the most frequent pathologies to affect the lips. Studies show that the most commonplace oral malignancy, squamous cell carcinoma (SCC), often emerges from AC lesions. Invasive diagnostic techniques performed on the lips carry a high risk of complications, but reflectance confocal microscopy (RCM), a non-invasive skin imaging technique, may change the current diagnostic pathway. This retrospective study was aimed at consolidating the RCM diagnostic criteria for AC and lip SCC. The study was conducted in two tertiary care centers in Bucharest, Romania. We included adults with histopathologically confirmed AC and SCC who also underwent RCM examination. Of the twelve lesions included in the study, four were AC and eight were SCC. An atypical honeycomb pattern and the presence of target cells in the epidermis were RCM features associated with AC. SCC was typified by the presence of complete disruption of the epidermal architecture and dermal inflammatory infiltrates. The mean blood vessel diameter in SCC was 18.55 µm larger than that in AC (p = 0.006) and there was no significant difference (p = 0.64) in blood vessel density, as measured by RCM, between SCC and AC. These data confirm that RCM can be useful for the in vivo distinction between AC and lip SCC.


2020 ◽  
Vol 26 (6) ◽  
pp. 883-890
Author(s):  
Amanda Mota ◽  
Juan Manuel Piñeiro‐Maceira ◽  
Carlos Barcaui

Author(s):  
Arianna Rizzo ◽  
Diletta Fiorani ◽  
Laura Lazzeri ◽  
Paolo Taddeucci ◽  
Pietro Rubegni ◽  
...  

2021 ◽  
Vol 14 (1) ◽  
pp. e240507
Author(s):  
Mihai Lupu ◽  
Vlad Mihai Voiculescu ◽  
Cristina Vajaitu ◽  
Olguta Anca Orzan

Author(s):  
Cristian Navarrete‐Dechent ◽  
Miguel Cordova ◽  
Saud Aleissa ◽  
Alexander Shoushtari ◽  
Travis J. Hollmann ◽  
...  

Author(s):  
Samavia Khan ◽  
Nadiya Chuchvara ◽  
Jennifer Cucalon ◽  
Attiya Haroon ◽  
Babar Rao

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