scholarly journals Increased heterogeneity of airway calibre in adult rats after hypoxia-induced intrauterine growth restriction

Respirology ◽  
2017 ◽  
Vol 22 (7) ◽  
pp. 1329-1335 ◽  
Author(s):  
Kimberley C.W. Wang ◽  
Jude S. Morton ◽  
Sandra T. Davidge ◽  
Alexander N. Larcombe ◽  
Alan L. James ◽  
...  
Keyword(s):  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Adult Rats ◽  
Intrauterine Growth ◽  
Airway Calibre

scholarly journals Plasma lipid levels and body weight altered by intrauterine growth restriction and postnatal fructose diet in adult rats

2012 ◽  
Vol 73 (2) ◽  
pp. 155-162 ◽  
Author(s):  
Elina Malo ◽  
Meiju Saukko ◽  
Merja Santaniemi ◽  
Mirella Hietaniemi ◽  
Eveliina Lammentausta ◽  
...  
Keyword(s):  
Body Weight ◽  
Intrauterine Growth Restriction ◽  
Plasma Lipid ◽  
Growth Restriction ◽  
Lipid Levels ◽  
Adult Rats ◽  
Intrauterine Growth

Intrauterine growth restriction and postnatal high-protein diet affect the kidneys in adult rats

Nutrition ◽  
2011 ◽  
Vol 27 (3) ◽  
pp. 364-371 ◽  
Author(s):  
Qian Shen ◽  
Hong Xu ◽  
Li-Ming Wei ◽  
Jing Chen ◽  
Hai-Mei Liu
Keyword(s):  
Intrauterine Growth Restriction ◽  
High Protein Diet ◽  
Growth Restriction ◽  
High Protein ◽  
Protein Diet ◽  
Adult Rats ◽  
Intrauterine Growth

scholarly journals Intrauterine growth restriction increases the preference for palatable foods and affects sensitivity to food rewards in male and female adult rats

2015 ◽  
Vol 1618 ◽  
pp. 41-49 ◽  
Author(s):  
Roberta Dalle Molle ◽  
Daniela Pereira Laureano ◽  
Márcio Bonesso Alves ◽  
Tatiane Madeira Reis ◽  
Mina Desai ◽  
...  
Keyword(s):  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Female Adult ◽  
Adult Rats ◽  
Male And Female ◽  
Intrauterine Growth

scholarly journals Gender-specific effects of intrauterine growth restriction on the adipose tissue of adult rats: a proteomic approach

2015 ◽  
Vol 13 (1) ◽  
Author(s):  
Adriana Pereira de Souza ◽  
Amanda Paula Pedroso ◽  
Regina Lúcia Harumi Watanabe ◽  
Ana Paula Segantine Dornellas ◽  
Valter Tadeu Boldarine ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Adult Rats ◽  
Intrauterine Growth ◽  
Specific Effects ◽  
Proteomic Approach ◽  
Gender Specific

scholarly journals Intrauterine growth restriction coupled with hyperglycemia: effects on cardiac structure in adult rats

2012 ◽  
Vol 72 (4) ◽  
pp. 344-351 ◽  
Author(s):  
Kyungjoon Lim ◽  
Paul Lombardo ◽  
Michal Schneider-Kolsky ◽  
M. Jane Black
Keyword(s):  
Intrauterine Growth Restriction ◽  
Growth Restriction ◽  
Cardiac Structure ◽  
Adult Rats ◽  
Intrauterine Growth

scholarly journals Intrauterine Growth Restriction Weakens Anticontractile Influence of NO in Coronary Arteries of Adult Rats 

2021 ◽  
Author(s):  
Ekaterina Selivanova ◽  
Anastasia Shvetsova ◽  
Lyubov Shilova ◽  
Olga Tarasova ◽  
Dina Gaynullina
Keyword(s):  
Coronary Arteries ◽  
Intrauterine Growth Restriction ◽  
Rho Kinase ◽  
Growth Restriction ◽  
Mesenteric Arteries ◽  
Adult Rats ◽  
Intrauterine Growth ◽  
Adrenoceptor Agonist ◽  
Rhoa Protein ◽  
Cardiac Disorders

Abstract Intrauterine growth restriction (IUGR) is one of the most common pathologies of pregnancy. The cardiovascular consequences of IUGR do not disappear in adulthood and can manifest themselves in pathological alterations of vasomotor control. The hypothesis was tested that IUGR weakens anticontractile influence of NO and augments procontractile influence of Rho-kinase in arteries of adult offspring. To model IUGR in the rat, dams were 50% food restricted starting from the gestational day 11 till delivery. Mesenteric and coronary arteries of male offspring were studied at the age of 3 months using wire myography, qPCR, and Western Blotting. Contractile responses of mesenteric arteries to α1-adrenoceptor agonist methoxamine as well as influences of NO and Rho-kinase did not differ between control and IUGR rats. However, coronary arteries of IUGR rats demonstrated elevated contraction to thromboxane A2 receptor agonist U46619 due to weakened anticontractile influence of NO and enhanced role of Rho-kinase in the endothelium. This was accompanied by reduced abundance of SODI protein and elevated content of RhoA protein in coronary arteries of IUGR rats. IUGR considerably changes the regulation of coronary vascular tone in adulthood and, therefore, can serve as a risk factor for the development of cardiac disorders.

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