scholarly journals Birth Outcomes in a Prospective Pregnancy-Birth Cohort Study of Environmental Risk Factors in Kuwait: The TRACER Study

2016 ◽  
Vol 30 (4) ◽  
pp. 408-417 ◽  
Author(s):  
Mohammad AlSeaidan ◽  
Rihab Al Wotayan ◽  
Costas A. Christophi ◽  
Massouma Al-Makhseed ◽  
Yara Abu Awad ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Birth Cohort ◽  
Birth Outcomes ◽  
Environmental Risk ◽  
Environmental Risk Factors ◽  
Birth Cohort Study ◽  
Tracer Study

Risk Factors for Antenatal Depression and Associations with Infant Birth Outcomes: Results From a South African Birth Cohort Study

2015 ◽  
Vol 29 (6) ◽  
pp. 505-514 ◽  
Author(s):  
Kirsty Brittain ◽  
Landon Myer ◽  
Nastassja Koen ◽  
Sheri Koopowitz ◽  
Kirsten A. Donald ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
South African ◽  
Birth Cohort ◽  
Birth Outcomes ◽  
Antenatal Depression ◽  
Birth Cohort Study ◽  
Infant Birth Outcomes ◽  
Infant Birth

Genetic and Environmental Risk Factors for Alcoholism: A 16-Year Longitudinal Cohort Study

2019 ◽  
Author(s):  
I-Chao Liu ◽  
Shu-Fen Liao ◽  
Lawrence Shih-Hsin ◽  
Susan Shur-Fen Gau ◽  
Wen-Chung Lee ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Environmental Risk ◽  
Environmental Risk Factors ◽  
Longitudinal Cohort Study ◽  
Longitudinal Cohort

scholarly journals 1459Socioeconomic position influence on the early-life individual exposome in the Italian NINFEA birth cohort

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Costanza Pizzi ◽  
Chiara Moccia ◽  
Giovenale Moirano ◽  
Antonio d'Errico ◽  
Milena Maule ◽  
...  
Keyword(s):  
Risk Factors ◽  
Urban Environment ◽  
Birth Cohort ◽  
Environmental Risk ◽  
Early Life ◽  
Diversity Index ◽  
Hierarchical Cluster ◽  
Environmental Risk Factors ◽  
Birth Cohorts ◽  
Exposure Pattern

Abstract Background Early exposure to unhealthy lifestyles and environmental risk factors is known to affect health throughout the life-course. There is also evidence that the exposure patterns are influenced by the socioeconomic position (SEP). Methods We use the data of the Turin participants of the Italian NINFEA birth cohort (n∼2500) to study how family SEP drives the early life exposome. SEP at birth is measured through the EHII (Equivalized Household Income Indicator), while the exposome includes urban environment, diet and lifestyle exposures measured during infancy. We use standard regression models to evaluate the effect of EHII on each exposome variable accounting for multiple comparison and potential confounders (Drivers-Exposome Wide Association Study – DExWAS) and the hierarchical clustering on the principal components approach to identify groups with similar exposure pattern. Results The DExWAS show that low EHII is associated with lower consumption of fruit and vegetables, lower levels of NO2, building and facilities densities, traffic, walkability and connectivity index, higher land-use diversity index, and higher exposure to pets. The hierarchical cluster analysis identifies three groups, with subjects belonging to the cluster characterized by higher level of urban environment risk factors and a healthier diet having a higher mean EHII. Conclusions These SEP-early life exposome analyses will be replicated in several European birth cohorts participating in the H2020 ATHLETE and LifeCycle projects. Key messages In the Italian city of Turin children from low SEP family are exposed to higher levels of environmental risk factors and unhealthy lifestyles during infancy.

scholarly journals The University of Zimbabwe College of Health Sciences (UZ-CHS) BIRTH COHORT study: rationale, design and methods

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Kerina Duri ◽  
◽  
Felicity Z. Gumbo ◽  
Privilege T. Munjoma ◽  
Precious Chandiwana ◽  
...  
Keyword(s):  
Cohort Study ◽  
Amniotic Fluid ◽  
Birth Cohort ◽  
Birth Outcomes ◽  
Early Life ◽  
Health Sciences ◽  
Birth Cohort Study ◽  
Adverse Birth Outcomes ◽  
The University ◽  
University Of Zimbabwe

Abstract Background Commencing lifelong antiretroviral therapy (ART) immediately following HIV diagnosis (Option B+), has greatly improved maternal-infant health. Thus, large and increasing numbers of HIV-infected women are on ART during pregnancy, a situation concurrently increasing numbers of HIV-exposed-uninfected (HEU) infants. Compared to their HIV-unexposed-uninfected (HUU) counterparts, HEU infants show higher rates of adverse birth outcomes, mortality, infectious/non-communicable diseases including impaired growth and neurocognitive development. There is an urgent need to understand the impact of HIV and early life ART exposures, immune-metabolic dysregulation, comorbidities and environmental confounders on adverse paediatric outcomes. Methods Six hundred (600) HIV-infected and 600 HIV-uninfected pregnant women ≥20 weeks of gestation will be enrolled from four primary health centres in high density residential areas of Harare. Participants will be followed up as mother-infant-pairs at delivery, week(s) 1, 6, 10, 14, 24, 36, 48, 72 and 96 after birth. Clinical, socio-economic, nutritional and environmental data will be assessed for adverse birth outcomes, impaired growth, immune/neurodevelopment, vertical transmission of HIV, hepatitis-B/C viruses, cytomegalovirus and syphilis. Maternal urine, stool, plasma, cord blood, amniotic fluid, placenta and milk including infant plasma, dried blood spot and stool will be collected at enrolment and follow-up visits. The composite primary endpoint is stillbirth and infant mortality within the first two years of life in HEU versus HUU infants. Maternal mortality in HIV-infected versus -uninfected women is another primary outcome. Secondary endpoints include a range of maternal and infant outcomes. Sub-studies will address maternal stress and malnutrition, maternal-infant latent tuberculosis, Helicobacter pylori infections, immune-metabolomic dysregulation including gut, breast milk and amniotic fluid dysbiosis. Discussion The University of Zimbabwe-College of Health-Sciences-Birth-Cohort study will provide a comprehensive assessment of risk factors and biomarkers for HEU infants’ adverse outcomes. This will ultimately help developing strategies to mitigate effects of maternal HIV, early-life ART exposures and comorbidities on infants’ mortality and morbidity. Trial registration ClinicalTrial.gov Identifier: NCT04087239. Registered 12 September 2019.

Prevalence of and risk factors for atopic dermatitis: A birth cohort study of infants in southeast Turkey

2016 ◽  
Vol 44 (3) ◽  
pp. 214-220 ◽  
Author(s):  
D. Doğruel ◽  
G. Bingöl ◽  
D.U. Altıntaş ◽  
M. Yılmaz ◽  
S.G. Kendirli
Keyword(s):  
Risk Factors ◽  
Atopic Dermatitis ◽  
Cohort Study ◽  
Birth Cohort ◽  
Birth Cohort Study

Exploring the risk factors for early‐life sugar consumption: a birth cohort study

2020 ◽  
Author(s):  
Carlos Alberto Feldens ◽  
Márcia Regina Vítolo ◽  
Renata Rocha Maciel ◽  
Paola Seffrin Baratto ◽  
Priscila Humbert Rodrigues ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Birth Cohort ◽  
Early Life ◽  
Birth Cohort Study ◽  
Sugar Consumption
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