scholarly journals Vascular risk factors for male and female urgency urinary incontinence at age 68 years from a British birth cohort study

2018 ◽  
Vol 122 (1) ◽  
pp. 118-125 ◽  
Author(s):  
Alex Tsui ◽  
Diana Kuh ◽  
Linda Cardozo ◽  
Daniel Davis
2018 ◽  
Author(s):  
Alex Tsui ◽  
Diana Kuh ◽  
Linda Cardozo ◽  
Daniel Davis

AbstractObjectiveTo investigate the prevalence of UUI at age 68 and the contribution of vascular risk factors to male and female UUI pathogenesis in addition to the associations with raised BMISubjects and methods1762 participants were from the MRC National Survey for Health and Development (NSHD) birth cohort, who answered the International Consultation on Incontinence Questionnaire short form (ICIQ-SF) at age 68. Logistic regression was used to estimate associations between UUI and earlier life vascular risk factors including: lipid status, diabetes, hypertension, body mass index (BMI), previous stroke or transient ischaemic attack (TIA) diagnosis; adjusting for smoking status, physical activity, co-presentation of SUI symptoms, educational attainment and in women only, type of menopause, age at period cessation and use of hormone replacement therapy.ResultsUUI was reported by 12% of men and 19% of women at 68. Female sex, previous stroke or TIA diagnosis, increased BMI and hypertension (in men only) at age 60-64 were independent risk factors for UUI. Female sex, increased BMI and a previous diagnosis of stroke/ TIA increased the relative risk of more severe UUI symptoms. Type and timing of menopause and HRT use did not alter the estimated associations between UUI and vascular risk factors in women.ConclusionMultifactorial mechanisms lead to UUI and vascular risk factors may contribute to pathogenesis of bladder overactivity in addition to higher BMI. Severe UUI appears to be a distinct presentation with more specific contributory mechanisms than milder UUI.


2016 ◽  
Vol 44 (3) ◽  
pp. 214-220 ◽  
Author(s):  
D. Doğruel ◽  
G. Bingöl ◽  
D.U. Altıntaş ◽  
M. Yılmaz ◽  
S.G. Kendirli

Author(s):  
Carlos Alberto Feldens ◽  
Márcia Regina Vítolo ◽  
Renata Rocha Maciel ◽  
Paola Seffrin Baratto ◽  
Priscila Humbert Rodrigues ◽  
...  

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Wilfried Karmaus ◽  
Nandini Mukherjee ◽  
Vimala Devi Janjanam ◽  
Su Chen ◽  
Hongmei Zhang ◽  
...  

2007 ◽  
Vol 23 (2) ◽  
pp. 347-354 ◽  
Author(s):  
Ana M. B. Menezes ◽  
Pedro C. Hallal ◽  
Bernardo L. Horta

In a prospective birth cohort study in Brazil, the prevalence and early risk factors for smoking in adolescence were investigated. All 1982 hospital-born children in Pelotas, Rio Grande do Sul, Brazil, were enrolled in a birth cohort study (N = 5,914; boys: 3,037; girls: 2,877). All male participants were searched in 2000 when enrolling in the national army, and 78.8% were traced. In 2001, a systematic sample of 473 girls was interviewed, representing a follow-up rate of 69.1%. Among males, 48.6% (95%CI: 46.6-50.7) had ever tried smoking and 15.8% (95%CI: 14.3-17.3) were daily smokers. Among females, 53.1% (95%CI: 48.6-57.6) had ever tried smoking and 15.4% (95%CI: 12.1-18.7) were daily smokers. Boys born to single mothers and those with fathers with low schooling were more likely to smoke in adolescence. Girls from low-income families, with mothers who smoked during pregnancy, and fathers with alcohol-related problems were more likely to smoke. Although the smoking prevalence was similar in boys and girls, risk factors for smoking were different between the sexes. Social environment appears to be the strongest predictor of tobacco use in adolescence.


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