Protective effect of mango (Mangifera indicaL.) against UVB-induced skin aging in hairless mice

2013 ◽  
Vol 29 (2) ◽  
pp. 84-89 ◽  
Author(s):  
Jae Hyoung Song ◽  
Eun Young Bae ◽  
Goya Choi ◽  
Jin Won Hyun ◽  
Mi Young Lee ◽  
...  
Keyword(s):  
Protective Effect ◽  
Skin Aging ◽  
Hairless Mice

scholarly journals Protective effect of taurine on UVB-induced skin aging in hairless mice

2021 ◽  
Vol 141 ◽  
pp. 111898
Author(s):  
Tomohisa Yoshimura ◽  
Chika Manabe ◽  
Yuki Inokuchi ◽  
Chikako Mutou ◽  
Tohru Nagahama ◽  
...  
Keyword(s):  
Protective Effect ◽  
Skin Aging ◽  
Hairless Mice

scholarly journals Anti-Aging Potential of Extracts from Washingtonia filifera Seeds

Plants ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 151
Author(s):  
Benedetta Era ◽  
Sonia Floris ◽  
Valeria Sogos ◽  
Clara Porcedda ◽  
Alessandra Piras ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Protective Effect ◽  
Pharmaceutical Preparation ◽  
Human Keratinocytes ◽  
Inhibitory Effect ◽  
Skin Aging ◽  
Stressed Cells ◽  
Collagenase Inhibition ◽  
Washingtonia Filifera ◽  
Seed Extracts

The aim of this study was to test the inhibitory effect of fruit extracts from Washingtonia filifera on skin aging-related enzymes. The pulp extracts did not exert a significant enzyme inhibition while seed extracts from W. filifera exhibit anti-elastase, anti-collagenase, and anti-tyrosinase activities. Tyrosinase was mildly inhibited while a stronger effect was observed with respect to elastase and collagenase inhibition. Alcoholic extracts provided better results than aqueous extracts. Among them, methanol extracts showed the prominent enzyme inhibitory activities being IC50 value for elastase and collagenase comparable and even better than the reference compound. The inhibition mode of the most active extracts was investigated by Lineweaver-Burk plot analysis. Seed extracts from W. filifera were also investigated for their photo-protective effect by Mansur equation and the antioxidant activity of W. filifera extract was evaluated in oxidative-stressed cells. To evaluate the safety of the extract, the effect on cell viability of human keratinocytes cells was analyzed. Methanol extract presented the best photo-protective effect and exerted an antioxidant activity in a cellular system with no cytotoxic effect. The overall results demonstrate that W. filifera extracts are promising sources of bioactive compounds that could be used in cosmetic and pharmaceutical preparation.

scholarly journals Oligomeric Procyanidin Nanoliposomes Prevent Melanogenesis and UV Radiation-Induced Skin Epithelial Cell (HFF-1) Damage

Molecules ◽  
2020 ◽  
Vol 25 (6) ◽  
pp. 1458 ◽  
Author(s):  
Yashu Chen ◽  
Fenghong Huang ◽  
David Julian McClements ◽  
Bijun Xie ◽  
Zhida Sun ◽  
...  
Keyword(s):  
Protective Effect ◽  
Fibroblast Cell ◽  
Skin Aging ◽  
Ultraviolet B ◽  
Protective Effects ◽  
Protection Mechanism ◽  
Uva Irradiation ◽  
Culture Model ◽  
Radiation Induced ◽  
Human Foreskin Fibroblast Cell

The potential protective effect of nanoliposomes loaded with lotus seedpod oligomeric procyanidin (LSOPC) against melanogenesis and skin damaging was investigated. Fluorescence spectroscopy showed that, after encapsulation, the LSOPC-nanoliposomes still possessed strong inhibitory effects against melanogenesis, reducing the activity of both monophenolase and diphenolase. Molecular docking indicated that LSOPC could generate intense interactive configuration with tyrosinase through arene–H, arene–arene, and hydrophobic interaction. An ultraviolet radiated cell-culture model (human foreskin fibroblast cell (HFF-1)) was used to determine the protective effects of the LSOPC-nanoliposomes against skin aging and damage. Results showed that LSOPC-nanoliposomes exerted the highest protective effects against both ultraviolet B (UVB) and ultraviolet A (UVA) irradiation groups compared with non-encapsulated LSOPC and a control (vitamin C). Superoxide dismutase (SOD) and malonaldehyde (MDA) assays demonstrated the protection mechanism may be related to the anti-photooxidation activity of the procyanidin. Furthermore, a hydroxyproline assay suggested that the LSOPC-nanoliposomes had a strong protective effect against collagen degradation and/or synthesis after UVA irradiation.

scholarly journals Protective Effect of Indole-3-Pyruvate against Ultraviolet B-Induced Damage to Cultured HaCaT Keratinocytes and the Skin of Hairless Mice

PLoS ONE ◽  
2014 ◽  
Vol 9 (5) ◽  
pp. e96804 ◽  
Author(s):  
Reiji Aoki ◽  
Ayako Aoki-Yoshida ◽  
Chise Suzuki ◽  
Yoshiharu Takayama
Keyword(s):  
Protective Effect ◽  
Ultraviolet B ◽  
Hacat Keratinocytes ◽  
Hairless Mice

scholarly journals Fermentation of Blackberry with L. plantarum JBMI F5 Enhance the Protection Effect on UVB-Mediated Photoaging in Human Foreskin Fibroblast and Hairless Mice through Regulation of MAPK/NF-κB Signaling

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2429
Author(s):  
Ha-Rim Kim ◽  
Da-Hye Jeong ◽  
Sol Kim ◽  
Sang-Wang Lee ◽  
Hong-Sig Sin ◽  
...  
Keyword(s):  
Uv Irradiation ◽  
Nuclear Factor Κb ◽  
Skin Aging ◽  
Human Foreskin Fibroblast ◽  
Enzyme Inactivation ◽  
Mitogen Activated Protein Kinase ◽  
Potential Candidate ◽  
Hairless Mice ◽  
Mitogen Activated Protein

Chronic and extensive exposure of ultraviolet (UV)-irradiation causes human skin sunburn, inflammation, or photoaging, which is associated with downregulated collagen synthesis. This study investigated the effects of fermented blackberry (Rubus fruticosus B., FBB) by Lactobacillus plantarum JBMI F5 (LP) on UVB-induced photoaging in human foreskin fibroblast (Hs68) as well as in SKH-1 hairless mice. FBB pretreatment inhibited UVB-mediated type-1 procollagen degradation, matrix metalloproteinase (MMP)-1 and MMP-2 protein expression, and suppressed nuclear factor-κB (NF-κB) activation as well as mitogen-activated protein kinase (MAPK) phosphorylation in Hs68. In addition, FBB administration diminished the wrinkle formation in dorsal skin and epidermal thickening in UVB-irradiated hairless mice. Moreover, UVB-induced Type-1 procollagen reduction and antioxidant enzyme inactivation were reversed by FBB administration. These results suggest that FBB may have antiphotoaging effects on UVB-induced wrinkle formation by maintaining the extracellular matrix density in the dermis, which occurs via regulation of reactive oxygen species and related MAPK and NF-κB signaling. Therefore, FBB can be a potential candidate for protecting skin aging against UV irradiation.

The protective effect ofKaempferia parvifloraextract on UVB-induced skin photoaging in hairless mice

2014 ◽  
Vol 30 (5) ◽  
pp. 237-245 ◽  
Author(s):  
Ji-Eun Park ◽  
Hee-Bong Pyun ◽  
Seon Wook Woo ◽  
Jae-Hong Jeong ◽  
Jae-Kwan Hwang
Keyword(s):  
Protective Effect ◽  
Hairless Mice ◽  
Skin Photoaging

scholarly journals Protective effect of (-)-epigallocatechin gallate on ultraviolet b-induced skin damage in hairless mice

2016 ◽  
Vol 15 (6) ◽  
pp. 1183 ◽  
Author(s):  
Chang Liu ◽  
Xin-Qiang Zheng ◽  
Li-Ping Xiang ◽  
Jian-Liang Lu ◽  
Curt Anthony Polito ◽  
...  
Keyword(s):  
Protective Effect ◽  
Epigallocatechin Gallate ◽  
Ultraviolet B ◽  
Skin Damage ◽  
Hairless Mice

scholarly journals Protective Effect of Fucoxanthin against UVB-Induced Skin Photoaging in Hairless Mice

2011 ◽  
Vol 75 (4) ◽  
pp. 757-760 ◽  
Author(s):  
Itaru URIKURA ◽  
Tatsuya SUGAWARA ◽  
Takashi HIRATA
Keyword(s):  
Protective Effect ◽  
Hairless Mice ◽  
Skin Photoaging
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