scholarly journals Oligomeric Procyanidin Nanoliposomes Prevent Melanogenesis and UV Radiation-Induced Skin Epithelial Cell (HFF-1) Damage

Molecules ◽  
2020 ◽  
Vol 25 (6) ◽  
pp. 1458 ◽  
Author(s):  
Yashu Chen ◽  
Fenghong Huang ◽  
David Julian McClements ◽  
Bijun Xie ◽  
Zhida Sun ◽  
...  
Keyword(s):  
Protective Effect ◽  
Fibroblast Cell ◽  
Skin Aging ◽  
Ultraviolet B ◽  
Protective Effects ◽  
Protection Mechanism ◽  
Uva Irradiation ◽  
Culture Model ◽  
Radiation Induced ◽  
Human Foreskin Fibroblast Cell

The potential protective effect of nanoliposomes loaded with lotus seedpod oligomeric procyanidin (LSOPC) against melanogenesis and skin damaging was investigated. Fluorescence spectroscopy showed that, after encapsulation, the LSOPC-nanoliposomes still possessed strong inhibitory effects against melanogenesis, reducing the activity of both monophenolase and diphenolase. Molecular docking indicated that LSOPC could generate intense interactive configuration with tyrosinase through arene–H, arene–arene, and hydrophobic interaction. An ultraviolet radiated cell-culture model (human foreskin fibroblast cell (HFF-1)) was used to determine the protective effects of the LSOPC-nanoliposomes against skin aging and damage. Results showed that LSOPC-nanoliposomes exerted the highest protective effects against both ultraviolet B (UVB) and ultraviolet A (UVA) irradiation groups compared with non-encapsulated LSOPC and a control (vitamin C). Superoxide dismutase (SOD) and malonaldehyde (MDA) assays demonstrated the protection mechanism may be related to the anti-photooxidation activity of the procyanidin. Furthermore, a hydroxyproline assay suggested that the LSOPC-nanoliposomes had a strong protective effect against collagen degradation and/or synthesis after UVA irradiation.

Photo-protective effect of Polysiphonia morrowii Harvey against ultraviolet B radiation-induced keratinocyte damage

2012 ◽  
Vol 55 (2) ◽  
pp. 149-158 ◽  
Author(s):  
Mei Jing Piao ◽  
Hee Kyoung Kang ◽  
Eun Sook Yoo ◽  
Young Sang Koh ◽  
Dong Sam Kim ◽  
...  
Keyword(s):  
Protective Effect ◽  
Ultraviolet B ◽  
Ultraviolet B Radiation ◽  
Radiation Induced

scholarly journals Momordica and Pycnogenol Can Tolerate Imazamox Induced Toxicity in L929 Cells Line: In Vitro Study

Proceedings ◽  
2018 ◽  
Vol 2 (25) ◽  
pp. 1584
Author(s):  
Ali Taghizadehghalehjoughi ◽  
Betul Cicek
Keyword(s):  
Protective Effect ◽  
Cell Line ◽  
Low Dose ◽  
Antioxidant Activities ◽  
Fibroblast Cell ◽  
High Dose ◽  
Protective Effects ◽  
Fibroblast Cell Line ◽  
Cell Viability Assay ◽  
L929 Fibroblast

Undesirable side effects that result from the random use of herbicides in developing countries are widespread. Imazamox is a widely used herbicide and has toxic effect on humans. Momordica charantia has been reported to possess many benefits and medicinal properties. Pycnogenol (PYC) is a natural plant extract from the bark of Pinus pinaster Aiton and has potent antioxidant activities. The aim of this study was to evaluate the protective effects of pycnogenol and momardica on induced imazamox toxicity effects on L929 fibroblast cell line. L929 fibroblast cells were cultured in the appropriate culture medium. Toxic concentration of imazamox 250 μM, were administered 30 min prior to momordica and pycnogenol (10−1–10−5 concentration) on L929 fibroblast cell line for 24 h. The cell viability assay was determined by using MTT test. TAC-TOS analysis were used to evaluate antioxidant and oxidant status. According to our study pycnogenol high dose showned protective effect whereas momordica low dose showned protective effect p < 0.05. In current study pycnogenol increased TAC capacity in high dose but in lower dose pycnogenol did not show any promise (p < 0.05). Momordica results showed correlation with MTT result. According to this analyse momordica only in low dose increased anti oxidant capacity and in addition, only in low dose TOS level were decreased (p > 0.05). In conclusion momordica and pycnogenol showed promise to reduced imazamox toxicity.

Protective Effect of Cerium Ion Against Ultraviolet B Radiation-Induced Water Stress in Soybean Seedlings

2011 ◽  
Vol 146 (3) ◽  
pp. 381-387 ◽  
Author(s):  
Chun Xia Mao ◽  
Min Min Chen ◽  
Lei Wang ◽  
Hua Zou ◽  
Chan Juan Liang ◽  
...  
Keyword(s):  
Water Stress ◽  
Protective Effect ◽  
Ultraviolet B ◽  
Soybean Seedlings ◽  
Ultraviolet B Radiation ◽  
Cerium Ion ◽  
Radiation Induced

Protective effect of PACAP against ultraviolet B radiation-induced human corneal endothelial cell injury

Neuropeptides ◽  
2020 ◽  
Vol 79 ◽  
pp. 101978 ◽  
Author(s):  
Grazia Maugeri ◽  
Agata Grazia D'Amico ◽  
Alessia Amenta ◽  
Salvatore Saccone ◽  
Concetta Federico ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Protective Effect ◽  
Cell Injury ◽  
Corneal Endothelial Cell ◽  
Ultraviolet B ◽  
Endothelial Cell Injury ◽  
Ultraviolet B Radiation ◽  
Radiation Induced
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