scholarly journals Change in obesity‐related metabolic abnormalities associated with body mass index improvement through life‐style intervention: A meta‐regression

2019 ◽  
Vol 21 (2) ◽  
pp. 173-193
Author(s):  
Rhys IB Matson ◽  
Rachel Perry ◽  
Linda P Hunt ◽  
Amanda HW Chong ◽  
Rhona Beynon ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Life Style ◽  
Metabolic Abnormalities ◽  
Life Style Intervention ◽  
Meta Regression

scholarly journals Pengembangan konsep comprehensive life style intervention pada tatanan sekolah melalui program: gerakan jajan sehat (GJS) di SD Negeri 01 Baruga Kota Kendari

2018 ◽  
pp. 13
Author(s):  
Nurhijrianti Akib
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Life Style ◽  
Ottawa Charter ◽  
Life Style Intervention

Jajan merupakan perilaku yang seringkali dikakukan oleh siswa sekolah dasar, yang dapat menimbulkan masalah apabila tidak memperhatikan mutu gizi, kebersihan, dan keamanan bahan pangan. Berdasarkan sampling dan uji laboratorium terhadap 10.429 sampel jajanan yang diambil dari 144 Sekolah Dasar/Madrasah Ibtidaiyah di 31 provinsi di seluruh Indonesia yang dilakukan oleh Badan Pengawas Obat dan Makanan (BPOM) pada tahun 2014 tercatat bahwa 2.484 (23,8%) dari sampel jajanan tersebut tidak memenuhi syarat, disebabkan  karena kandungan bahan tambahan yang berbahaya. Tujuan dari penelitian ini yaitu untuk mengembangkan program : Gerakan Jajan Sehat (GJS) di SD Negeri 01 Baruga Kota Kendari yang diadopsi dari Konsep Comprehensive Life Style Intervention dari Ottawa Charter. Adapun program intervensi yang dikembangkan berdasarkan 5 dimensi Comprehensive Life Style Intervention pada tatanan sekolah yaitu : 1) Penerapan kebijakan kesehatan dengan aturan pelarang penjualan makanan tidak sehat dan menjual makanan yang sehat di sekolah, 2) Reorientasi pelayanan kesehatan yaitu dengan melakukan pengukuran BMI (Body Mass Index) dan pemeriksaan kesehatan, 3) Membangun lingkungan yang dapat mendukung kesehatan yaitu dengan pendidikan kesehatan pada staff sekolah, guru, dan orang tua serta penyediaan makanan yang sehat, 4) Penguatan aksi di komunitas, yaitu dengan mengintegrasikan perilaku sehat di rumah dan di sekolah, serta mengadakan kompetisi jajan sehat pada level individu di dalam kelas, 5) Mengembangkan keterampilan personal yaitu dengan pendidikan kesehatan melalui berbagai metode permainan tentang gerakan jajan sehat.

scholarly journals Body Mass Index Change in Females After Short-Time Life Style Intervention Is Not Dependent on the FTO Polymorphisms

2011 ◽  
pp. 199-202 ◽  
Author(s):  
D. DLOUHÁ ◽  
P. SUCHÁNEK ◽  
V. LÁNSKÁ ◽  
J. A. HUBÁČEK
Keyword(s):  
Physical Activity ◽  
Body Mass Index ◽  
Body Mass ◽  
Life Style ◽  
Physical Activity Intervention ◽  
Exercise Program ◽  
Hdl Cholesterol ◽  
Life Style Intervention ◽  
The Mean ◽  
Short Time

Variants within the FTO gene are important determinants of body mass index (BMI), but their role in determination of BMI changes after combined dietary/physical activity intervention is unclear. We have analyzed 107 unrelated overweight non-diabetic Czech females (BMI over 27.5 kg/m2, age 49.2±12.3 years). FTO variants rs17817449 (first intron) and rs17818902 (third intron) were genotyped. The life style modification program (10 weeks) consisted of an age-matched reduction of energy intake and exercise program (aerobic exercise 4 times a week, 60 min each). The mean BMI before intervention was 32.8±4.2 kg/m2 and the mean achieved weight loss was 4.8±3.5 kg (5.3±3.5 %, max. –15.5 kg, min. +2.0 kg, p<0.01). No significant association between BMI decrease and FTO variants was found. Also waist-to-hip ratio, body composition (body fat, water, active tissue), lipid parameters (total, LDL and HDL cholesterol, triglycerides) glucose and hsCRP changes were independent on FTO variants. FTO variants rs17817449 and rs17818902 are not associated with BMI changes after combined short time dietary/physical activity intervention in overweight females.

Metformin treatment with or without life style changes in patients with polycystic ovary syndrome

2011 ◽  
Vol 152 (16) ◽  
pp. 628-632 ◽  
Author(s):  
Gyula Petrányi ◽  
Mária Zaoura-Petrányi
Keyword(s):  
Body Mass Index ◽  
Polycystic Ovary Syndrome ◽  
Treatment Period ◽  
Body Mass ◽  
Life Style ◽  
Polycystic Ovary ◽  
Glycaemic Index ◽  
Ovary Syndrome ◽  
Waist To Hip Ratio ◽  
Life Style Changes

Treatment with metformin three times 500 mg daily had been advised since 2002, to patients suffering from the polycystic ovary syndrome diagnosed by the Rotterdam criteria and who did not want to take contraceptive pills. More recently, life style changes have also been introduced to treatment recommendation: increased physical activity, low glycaemic index diet; also with calorie restriction for the obese patients. Aim: To assess the efficacy of the two treatment forms on clinical symptoms of the disease. Method: The metformin only historical control group (metformin monotherapy) consisted of 27 patients between the ages from 18 to 39 years (mean 29 years); to which was the age-matched metformin and life style changes group (triple basal therapy) of 29 patients compared. The following parameters were registered at the beginning and the end of a six-month treatment period: global acne score, Ferriman-Gallwey hirsutism score, body mass index, waist-to-hip circumference ratio, and menstrual cycles. Results: By the end of the treatment period, both acne and hirsutism scores improved significantly in both treatment groups (P<0.001); the improvements did not differ between them: acne 8.6±5.7 vs. 9.2±5.9 (P = 0.70); hirsutism 2.5±2.0 vs. 2.6±1.6 (P = 0.83). Body mass index and waist-to-hip ratio remained practically unchanged in the metformin only group: 0.26±1.0 kg/m2 (P = 0.21) and 0.001±0.02 (P = 0.71). Body mass index decreased in the triple therapy group by 0.91±1.1 kg/m2 (P<0.001); and waist-to-hip ratio by 0.019±0.03 (P<0.001). The decrease of the body mass index was more remarkable in overweight patients: 1.10±1.26 kg/m2 (P = 0.002) vs. 0.64±0.88 kg/m2 (P = 0.03) in lean patients. Recommendation on life style changes with metformin did not show further improvement of hyperandrogenic symptoms in comparison to metformin alone but the combined therapy diminished body size indexes. Conclusion: Authors recommend the triple basal treatment consisting of metformin, physical exercise and low glycaemic index diet to their patients with polycystic ovary syndrome for assessment of its long-term efficacy. Orv. Hetil., 2011, 152, 628–632.

scholarly journals Optimal cutoff values for anthropometric indices of obesity as discriminators of metabolic abnormalities in Korea: results from a Health Examinees study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sooyoung Cho ◽  
Aesun Shin ◽  
Ji-Yeob Choi ◽  
Sang Min Park ◽  
Daehee Kang ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Waist Circumference ◽  
Body Mass ◽  
Metabolic Abnormalities ◽  
Height Ratio ◽  
Optimal Cutoff ◽  
Waist To Hip Ratio ◽  
Cutoff Values ◽  
Waist To Height Ratio ◽  
Conicity Index

Abstract Background Obesity is well known as a risk factor for cardiovascular disease. We aimed to determine the performance of and the optimal cutoff values for obesity indices to discriminate the presence of metabolic abnormalities as a primary risk factor for cardiovascular diseases in a Health Examinees study (HEXA). Methods The current study analyzed 134,195 participants with complete anthropometric and laboratory information in a Health Examinees study, consisting of the Korean population aged 40 to 69 years. The presence of metabolic abnormality was defined as having at least one of the following: hypertension, hyperglycemia, or dyslipidemia. The area under the receiver operating characteristic curve (AUC) and 95% confidence intervals (CIs) were calculated for body mass index, waist to hip ratio, waist to height ratio, waist circumference, and conicity index. Results The AUC of metabolic abnormalities was the highest for waist-to-height ratio (AUC [95% CIs], 0.677 [0.672–0.683] among men; 0.691 [0.687–0.694] among women), and the lowest for the C index (0.616 [0.611–0.622] among men; 0.645 [0.641–0.649] among women) among both men and women. The optimal cutoff values were 24.3 kg/m2 for the body mass index, 0.887 for the waist-to-hip ratio, 0.499 for the waist-to-height ratio, 84.4 cm for waist circumference and 1.20 m3/2/kg1/2 for the conicity index among men, and 23.4 kg/m2 for the body mass index, 0.832 for the waist-to-hip ratio, 0.496 for the waist-to-height ratio, 77.0 cm for the waist circumference and 1.18 m3/2/kg1/2 for the conicity index among women. Conclusion The waist-to-height ratio is the best index to discriminate metabolic abnormalities among middle-aged Koreans. The optimal cutoff of obesity indices is lower than the international guidelines for obesity. It would be appropriate to use the indices for abdominal obesity rather than general obesity and to consider a lower level of body mass index and waist circumference than the current guidelines to determine obesity-related health problems in Koreans.

Body mass index and ovarian function are associated with endocrine and metabolic abnormalities in women with hyperandrogenic syndrome

2008 ◽  
Vol 158 (5) ◽  
pp. 711-719 ◽  
Author(s):  
S Cupisti ◽  
N Kajaia ◽  
R Dittrich ◽  
H Duezenli ◽  
M W Beckmann ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Insulin Sensitivity ◽  
Body Mass ◽  
Density Lipoprotein ◽  
Sex Hormone Binding Globulin ◽  
Oral Glucose ◽  
Sensitivity Index ◽  
Metabolic Abnormalities ◽  
Insulin Levels ◽  
Homeostatic Model

BackgroundThe aim of this study was to evaluate associations of clinical features, such as hirsutism, polycystic ovaries (PCOs), ovulatory dysfunction, and body mass index (BMI) ≥25 kg/m2, with metabolic abnormalities in hyperandrogenic women.MethodsHirsutism was based on the modified Ferriman–Gallwey score. Ovulatory function was classified as eumenorrhea, oligomenorrhea and amenorrhea, and PCOs were assessed using the ultrasound criteria recommended in the Rotterdam definition. An oral glucose tolerance test was performed. Different insulin resistance (IR) indices were calculated.ResultsHirsute women had significantly higher BMI, DHEA sulfate (DHEAS) and free androgen index (FAI), and significantly lower values for sex hormone-binding globulin (SHBG). Women with amenorrhea were younger in comparison to women with eumenorrhea and had significantly higher values for fasting insulin (FI) and 1- and 2-h insulin levels; lower values for glucose to insulin ratio (GIR), quantitative insulin sensitivity check index (QUICKI), and SHBG. Women with PCO had significantly higher levels of LH and low-density lipoprotein (LDL), whereas high-density lipoprotein (HDL) levels were significantly lower. Women with a BMI ≥25 kg/m2 had significantly higher values for age, fasting plasma glucose, FI, and 1- and 2-h glucose and insulin levels, homeostatic model for assessment of IR (HOMA-IR), homeostatic model for assessment of B-cell function (HOMA-B), and FAI, whereas their GIR, insulin sensitivity index, QUICKI, SHBG, and HDL were significantly lower.ConclusionsIn women with hyperandrogenic syndrome, BMI≥25 kg/m2 and amenorrhea appear to be associated with severe endocrine and metabolic abnormalities.

scholarly journals Correlates of overweight and obesity among school going children of Himachal Pradesh

2020 ◽  
Vol 5 (05) ◽  
pp. 146-150
Author(s):  
Minakshi Chimanchod ◽  
Vijay Chaudhary ◽  
Abhimanyu Kumar
Keyword(s):  
Body Mass Index ◽  
Children And Adolescents ◽  
Body Mass ◽  
Life Style ◽  
Food Habits ◽  
Overweight And Obesity ◽  
School Age Children ◽  
School Age ◽  
Adult Obesity ◽  
Obese Children

Overweight and obesity are important determinants of health leading to adverse metabolic changes and increase the risk of non-communicable diseases. Following the increase in adult obesity, the proportion of overweight and obese children and adolescents has also been increasing. Erroneous life style and food habits are mainly responsible for rising graph of obesity. Hence, the present study was undertaken to study the magnitude of overweight/obesity and its correlates among school-age children ranging from 5-15 years, on the basis of 85th and 95th percentile of body mass index (BMI). Result showed the prevalence of overweight and obesity as 10.33% and 3.33%, respectively. Among number of other correlates related with life style, Kapha predominant Prakriti evolved as an important predictor of obesity. Data of this study clearly delineates that obesity is an increasing malady in rural and semi urban populations also on the pattern of metro cities.

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