scholarly journals Body Mass Index Change in Females After Short-Time Life Style Intervention Is Not Dependent on the FTO Polymorphisms

2011 ◽  
pp. 199-202 ◽  
Author(s):  
D. DLOUHÁ ◽  
P. SUCHÁNEK ◽  
V. LÁNSKÁ ◽  
J. A. HUBÁČEK

Variants within the FTO gene are important determinants of body mass index (BMI), but their role in determination of BMI changes after combined dietary/physical activity intervention is unclear. We have analyzed 107 unrelated overweight non-diabetic Czech females (BMI over 27.5 kg/m2, age 49.2±12.3 years). FTO variants rs17817449 (first intron) and rs17818902 (third intron) were genotyped. The life style modification program (10 weeks) consisted of an age-matched reduction of energy intake and exercise program (aerobic exercise 4 times a week, 60 min each). The mean BMI before intervention was 32.8±4.2 kg/m2 and the mean achieved weight loss was 4.8±3.5 kg (5.3±3.5 %, max. –15.5 kg, min. +2.0 kg, p<0.01). No significant association between BMI decrease and FTO variants was found. Also waist-to-hip ratio, body composition (body fat, water, active tissue), lipid parameters (total, LDL and HDL cholesterol, triglycerides) glucose and hsCRP changes were independent on FTO variants. FTO variants rs17817449 and rs17818902 are not associated with BMI changes after combined short time dietary/physical activity intervention in overweight females.

2018 ◽  
Vol 52 (12) ◽  
pp. 999-1009 ◽  
Author(s):  
Kelly M Kenzik ◽  
Wendy Demark-Wahnefried ◽  
Patricia A Ganz ◽  
Graham Colditz ◽  
Cheryl L Rock ◽  
...  

AbstractBackgroundBreast cancer survivors rank fatigue (e.g., decreased vitality) as their number one concern affecting quality of life. Excess adiposity is associated with decreased vitality in breast cancer survivors, yet weight loss intervention trials report inconsistent effects on this parameter.MethodsThis is a secondary analysis of the Exercise and Nutrition to Enhance Recovery and Good Health for You trial, in which 692 overweight or obese breast cancer survivors ≤5 years from diagnosis, initiated weight loss interventions, and completed assessments semi-annually for 2 years. Assessments included the Godin Leisure-Time Exercise Questionnaire and the SF-36 MOS vitality subscale as an inverse measure of fatigue. Multilevel structural equation models estimated the direct effects of physical activity on vitality and indirect effects through body mass index (BMI) changes.ResultsWithin-person findings show that at assessments with greater physical activity, BMI was significantly lower (B = −0.07, p &lt; 0.001) and vitality was higher (B = 0.22, p &lt; 0.001). However, there was no direct relationship between lower BMI and higher vitality (B = −0.11, p = 0.262) after controlling for the relationship of physical activity with BMI and physical activity with vitality. The between-person indirect effect of physical activity change through BMI change to vitality was significant (B = 0.03, p &lt; 0.001). Participants whose physical activity was above the mean (B = 0.37, p &lt; 0.001) and whose BMI was below the mean (B = −1.05, p &lt; 0.001) were more likely to report greater vitality.ConclusionImprovements in vitality are primarily associated with increases in physical activity rather than BMI changes in this trial. Vitality was lower among survivors with higher BMI, although within-individual changes in BMI had no effect on vitality. Physical activity and weight loss share mechanistic links to vitality with physical activity potentially increasing (e.g., in an additive or synergistic manner) the effect of BMI reduction on vitality.


2013 ◽  
Vol 12 (1) ◽  
Author(s):  
Assoc. Prof. Dr. Ayiesah Ramli

Introduction: Obesity has been recognized as a major public health concern due to lack of physical activity and a sedentary lifestyle. Methods: This cross sectional study was carried out to determine the status of body mass index (BMI) and habitual physical activity level among staffs working in Military Hospital, Malacca using Habitual Physical Activity Questionnaire (HPAQ). Results: About 120 HPAQ were distributed and only 82 responded with 23(28%) of them males and 59 (72%) females, aged between 21 to 59 (40.52 ± 9.38) years old. Anthropometry analysis showed the mean weight of male respondents was 79.48 (± 16.33) and 70.95 (± 15.66) for the females. Body mass index (BMI) for males (33.61 ± 2.82) was almost similar to females ( 33.20± 2.95).The mean waist circumference of men was 93.26 (± 10.94)cm compared to 94.03 (± 11.98)cm in the females. Following categorization of BMI, 59% (n=48) are in the obese group, 24% (n=20) are overweight and only 17% (n=14) have an ideal body weight or normal BMI. Relationship between BMI and HPAQ demonstrated strong and significant correlation coefficient for habitual physical activity at work (r = 0.775, p < 0.001), sports (r = 0.735, p < 0.05) and leisure ( r = 0.713, p < 0.001). Conclusion: The staffs working in the Hospital demonstrated poor habitual physical activity which explains for the high incidence of obesity among the staffs. This requires measures to be taken to promote a healthier lifestyle among them.


2012 ◽  
Vol 24 (4) ◽  
pp. 331-337 ◽  
Author(s):  
Whye L. Cheah ◽  
Ching T. Chang ◽  
Rosalia Saimon

Abstract This study examined the relationship between perceived built environment attributes and physical activity, physical fitness and body weight among adolescents aged 14–16 years in Sarawak. This was a cross-sectional study, using multi-stage sampling. A set of questionnaires consisting of socio-demographic information, a self-administered physical activity checklist and a Neighborhood Environment Walkability Scale-Youth (NEWS-Y) was used. Body mass index (BMI) was measured and physical fitness was tested using a maximal multistage 20 m shuttle run test. Data analysis was done using SPSS version 17.0. A total of 316 respondents participated. The mean BMI for boys was almost equal to the mean BMI for girls. Only 7.9% of the sampled population was found to be overweight or obese. The overall mean duration spent per day on physical activity was 128.4 min (SD 118.43), with mean of 56.1 min (SD 73.94) after school time. Girls reported to spend longer each day taking physical activity before and during school. Boys were found to have significantly higher VO2max of 27.79±5.91 mL/kg/min as compared to girls (t=11.22, p<0.000). Based on comparison with other countries, the NEWS-Y scores indicated a mixture of low and high walkability neighborhoods. Respondents who had lower BMIs reported living in lower residential density areas and less risk of crime, and respondents who had better physical fitness reported less suitable infrastructure for walking. Promotion of exercise at all levels should be continuously encouraged as it would lead to improvement in the well-being of an individual.


2018 ◽  
pp. 13
Author(s):  
Nurhijrianti Akib

Jajan merupakan perilaku yang seringkali dikakukan oleh siswa sekolah dasar, yang dapat menimbulkan masalah apabila tidak memperhatikan mutu gizi, kebersihan, dan keamanan bahan pangan. Berdasarkan sampling dan uji laboratorium terhadap 10.429 sampel jajanan yang diambil dari 144 Sekolah Dasar/Madrasah Ibtidaiyah di 31 provinsi di seluruh Indonesia yang dilakukan oleh Badan Pengawas Obat dan Makanan (BPOM) pada tahun 2014 tercatat bahwa 2.484 (23,8%) dari sampel jajanan tersebut tidak memenuhi syarat, disebabkan  karena kandungan bahan tambahan yang berbahaya. Tujuan dari penelitian ini yaitu untuk mengembangkan program : Gerakan Jajan Sehat (GJS) di SD Negeri 01 Baruga Kota Kendari yang diadopsi dari Konsep Comprehensive Life Style Intervention dari Ottawa Charter. Adapun program intervensi yang dikembangkan berdasarkan 5 dimensi Comprehensive Life Style Intervention pada tatanan sekolah yaitu : 1) Penerapan kebijakan kesehatan dengan aturan pelarang penjualan makanan tidak sehat dan menjual makanan yang sehat di sekolah, 2) Reorientasi pelayanan kesehatan yaitu dengan melakukan pengukuran BMI (Body Mass Index) dan pemeriksaan kesehatan, 3) Membangun lingkungan yang dapat mendukung kesehatan yaitu dengan pendidikan kesehatan pada staff sekolah, guru, dan orang tua serta penyediaan makanan yang sehat, 4) Penguatan aksi di komunitas, yaitu dengan mengintegrasikan perilaku sehat di rumah dan di sekolah, serta mengadakan kompetisi jajan sehat pada level individu di dalam kelas, 5) Mengembangkan keterampilan personal yaitu dengan pendidikan kesehatan melalui berbagai metode permainan tentang gerakan jajan sehat.


2017 ◽  
Vol 135 (1) ◽  
pp. 50-56 ◽  
Author(s):  
Camila Weschenfelder ◽  
Aline Marcadenti ◽  
Airton Tetelbom Stein ◽  
Catarina Bertaso Andreatta Gottschall

ABSTRACT CONTEXT AND OBJECTIVE: The association of serum triglycerides plus waist circumference seems to be a good marker of cardiovascular risk and has been named the “hypertriglyceridemic waist” phenotype. The aim of our study was to investigate the association between the hypertriglyceridemic waist phenotype and HDL-cholesterol among patients with heart failure. DESIGN AND SETTING: Cross-sectional study in a tertiary-level hospital in southern Brazil. METHODS: We included patients with heart failure aged > 40 years. Anthropometric assessment (weight, height, waist and hip circumferences) was performed; body mass index (BMI) and waist-hip ratio were calculated and lipid measurements (serum total cholesterol, LDL-cholesterol, HDL-cholesterol and triglycerides) were collected. In men and women, respectively, waist circumference ≥ 94 cm and ≥ 80 cm, and triglycerides ≥ 150 mg/dl were considered abnormal and were used to identify the hypertriglyceridemic waist phenotype. Analyses of covariance were used to evaluate possible associations between levels of HDL-cholesterol and the hypertriglyceridemic waist phenotype, according to sex. RESULTS: 112 participants were included, of whom 62.5% were men. The mean age was 61.8 ± 12.3 years and the mean ejection fraction was 40.1 ± 14.7%. Men and woman presented mean HDL-cholesterol of 40.5 ± 14.6 and 40.9 ± 12.7 mg/dl, respectively. The prevalence of the hypertriglyceridemic waist phenotype was 25%. There was a significant difference in mean HDL-cholesterol between men with and without the hypertriglyceridemic waist phenotype (32.8 ± 14.2 versus 42.1 ± 13.7 mg/dl respectively; P = 0.04), even after adjustment for age, body mass index, type 2 diabetes mellitus, use of statins and heart failure etiology. CONCLUSIONS: The hypertriglyceridemic waist phenotype is significantly associated with lower HDL-cholesterol levels in men with heart failure.


Author(s):  
Godefroid K. Mabele ◽  
Constant N. Ekisawa ◽  
Christophe DELECLUSE ◽  
Teddy B.Linkoko ◽  
Nicaise K.Ngasa ◽  
...  

Background: Obesity has become a public health problem in the world today, especially in the workplace, where workers are subjected to long-term work in a sitting position and in front of computers. The absence of a program of structured physical exercises in our context on obesity in a professional environment in Kinshasa motivated us to carry out this study. Objective: To investigate the effect of a structured exercise program on the level of physical activity and energy expenditure of obese workers. Methods: In a 6-month follow-up study, 157 obese patients with a mean age of 47 ± 9.54 years were enrolled in a 3-day, one-hour structured exercise program. Day of moderate to high intensity and walking combined with a nutritional education (low calorie, high fiber and vitamins) at the Multimodal Freight Management Office of Kinshasa between January and June 2014. We used the paired Student's T test to compare continuous variables before and after the programs. Results: A significant increase was obtained in six months of the structured exercise program combined with nutrition education for most of the studied parameters: number of steps on the working day (p <0.0001) ; number of steps on the weekend (p <0.0001); energy expenditure on the working day (p <0.0001); energy expenditure on the weekend day (p<0.0001). In contrast, weight, Body Mass Index, Waist circumference and Hip Abdomen Ratio significantly decrease d respectively: weight (p<0.0001); Body Mass Index (p <0.0001); waist circumference (p < 0.0001); Hip Abdomen Ratio (p <0.0001).Conclusion: Structured exercise combined with nutrition education significantly increases the level of physical activity, energy expenditure and decreases weight, Body Mass Index, waist circumference and morbidity and mortality risk of obese workers.


2015 ◽  
Vol 3 (3) ◽  
pp. 1-8
Author(s):  
PN Okafor ◽  
PO Ukegbu ◽  
OC Godfrey ◽  
MC Ofoegbu ◽  
AC Uwaegbute

Assessment of lipid profile in some middle and upper class individuals based on their life-style and dietary habit was carried out using 35 volunteer human 19 males and 16 females. Their life-style and dietary habit were determined using a questionnaire. Anthropometric measurements of weight, height, waist and hip circumferences were taken, Body Mass Index (BMI) and waist hip ratio (WHR) were calculated, while the lipid profile was determined using standard biochemical proce-dures. The results of the anthropometric measurements showed that the mean weight, height and Body Mass Index (BMI) were 80.1±13.8 kg, 1.7±1.1 m, 26.4±4.9 kg m-2, respectively for the males and 78.5±16.5 kg, 1.6±1.2 m and 25.8±5.5 kg m-2, respectively for the females. There was no statisti-cally significant difference (p > 0.05) in all the anthropometric parameters measured for both sexes except for waist/height ratio (WHR). The results of the lipid profile showed that the mean total cholesterol (TC), High density lipoprotein-cholesterol (HDL-C) and triglycerides (TRG) were within normal reference range. Both sexes however, had mean low density lipoprotein-cholesterol (LDL-C) of 101.8±45.2 mg dL-1 and 119.5±43.7 mg dL-1 for males and females respectively. The total cholesterol/high density lipoprotein (TC/HDL-C) ratio revealed that mean values for the males and the females were 4.5±1.1 and 4.9±2.1 respectively. Correlation analysis showed positive correlations between BMI and LDL-C (r=0439; p=0.018), WHR and TAG (r=0.488; p=0.003), waist circumference (WC) and TRG (r=0.379; p=0.025). A high prevalence of overweight/obesity and dyslipidaemia (high LDL-C and triglycerides) were observed among the adults. Appropriate interventions such as regular exercise and periodic lipid profile screening should be advocated.Keywords: Lipid profile, dietary habit, anthropometry, Abia State


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