SOFA coagulation score and changes in platelet counts in severe acute kidney injury: Analysis from the randomized evaluation of normal versus augmented level (RENAL) study

Nephrology ◽  
2019 ◽  
Vol 24 (5) ◽  
pp. 518-525 ◽  
Author(s):  
Jin Lin ◽  
Martin Gallagher ◽  
Rinaldo Bellomo ◽  
Meili Duan ◽  
Konlawi Trongtrakul ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Platelet Counts ◽  
Randomized Evaluation ◽  
Injury Analysis

scholarly journals Platelet Counts, Acute Kidney Injury, and Mortality after Coronary Artery Bypass Grafting Surgery

2016 ◽  
Vol 124 (2) ◽  
pp. 339-352 ◽  
Author(s):  
Miklos D. Kertai ◽  
Shan Zhou ◽  
Jörn A. Karhausen ◽  
Mary Cooter ◽  
Edmund Jooste ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Odds Ratio ◽  
Artery Bypass ◽  
Kidney Injury ◽  
Bypass Grafting ◽  
Cabg Surgery ◽  
Platelet Counts ◽  
Postoperative Aki

Abstract Background Cardiac surgery requiring cardiopulmonary bypass is associated with platelet activation. Because platelets are increasingly recognized as important effectors of ischemia and end-organ inflammatory injury, the authors explored whether postoperative nadir platelet counts are associated with acute kidney injury (AKI) and mortality after coronary artery bypass grafting (CABG) surgery. Methods The authors evaluated 4,217 adult patients who underwent CABG surgery. Postoperative nadir platelet counts were defined as the lowest in-hospital values and were used as a continuous predictor of postoperative AKI and mortality. Nadir values in the lowest 10th percentile were also used as a categorical predictor. Multivariable logistic regression and Cox proportional hazard models examined the association between postoperative platelet counts, postoperative AKI, and mortality. Results The median postoperative nadir platelet count was 121 × 109/l. The incidence of postoperative AKI was 54%, including 9.5% (215 patients) and 3.4% (76 patients) who experienced stages II and III AKI, respectively. For every 30 × 109/l decrease in platelet counts, the risk for postoperative AKI increased by 14% (adjusted odds ratio, 1.14; 95% CI, 1.09 to 1.20; P < 0.0001). Patients with platelet counts in the lowest 10th percentile were three times more likely to progress to a higher severity of postoperative AKI (adjusted proportional odds ratio, 3.04; 95% CI, 2.26 to 4.07; P < 0.0001) and had associated increased risk for mortality immediately after surgery (adjusted hazard ratio, 5.46; 95% CI, 3.79 to 7.89; P < 0.0001). Conclusion The authors found a significant association between postoperative nadir platelet counts and AKI and short-term mortality after CABG surgery.

scholarly journals Monitoring peripheral perfusion in sepsis associated acute kidney injury: Analysis of mortality

PLoS ONE ◽  
2020 ◽  
Vol 15 (10) ◽  
pp. e0239770
Author(s):  
Ana Carolina de Miranda ◽  
Igor Alexandre Cortês de Menezes ◽  
Hipolito Carraro Junior ◽  
Alain Márcio Luy ◽  
Marcelo Mazza do Nascimento
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Peripheral Perfusion ◽  
Injury Analysis

Neutrophil, Lymphocyte, and Platelet Counts and Acute Kidney Injury After Cardiovascular Surgery

2018 ◽  
Vol 32 (1) ◽  
pp. 212-222 ◽  
Author(s):  
Chang-Hoon Koo ◽  
Dhong Eun Jung ◽  
Yoon Sang Park ◽  
Jungil Bae ◽  
Youn Joung Cho ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Cardiovascular Surgery ◽  
Kidney Injury ◽  
Platelet Counts

Andrographolide induced acute kidney injury: Analysis of 26 cases reported in Chinese Literature

Nephrology ◽  
2013 ◽  
Vol 19 (1) ◽  
pp. 21-26 ◽  
Author(s):  
Wu-Xing Zhang ◽  
Zhi-Min Zhang ◽  
Zhi-Qiang Zhang ◽  
Yang Wang ◽  
Wei Zhou
Keyword(s):  
Acute Kidney Injury ◽  
Chinese Literature ◽  
Kidney Injury ◽  
Injury Analysis
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