Worse In-Hospital Outcomes in Patients with Transient Ischemic Attack in Association with Acute Kidney Injury: Analysis of Nationwide In-Patient Sample

2014 ◽  
Vol 40 (3) ◽  
pp. 258-262 ◽  
Author(s):  
Fahad Saeed ◽  
Malik M. Adil ◽  
Ahmed A. Malik ◽  
Mushtaq H. Qureshi ◽  
Fadi Nahab
Keyword(s):  
Acute Kidney Injury ◽  
Transient Ischemic Attack ◽  
Kidney Injury ◽  
Hospital Outcomes ◽  
Patient Sample ◽  
Ischemic Attack ◽  
Injury Analysis

In-Hospital Outcomes of Patients with Acute Kidney Injury Following Acute Coronary Syndrome in a Tertiary level Hospital

2019 ◽  
Vol 5 (6) ◽  
Author(s):  
MSI Tipu Chowdhury ◽  
Khaled Md. Iqbal ◽  
Zahidul Mostafa ◽  
Md. Fakhrul Islam Khaled ◽  
Sadia Sultana ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Acute Coronary Syndrome ◽  
Kidney Injury ◽  
Tertiary Level ◽  
Hospital Outcomes ◽  
Coronary Syndrome ◽  
Level Hospital

scholarly journals Monitoring peripheral perfusion in sepsis associated acute kidney injury: Analysis of mortality

PLoS ONE ◽  
2020 ◽  
Vol 15 (10) ◽  
pp. e0239770
Author(s):  
Ana Carolina de Miranda ◽  
Igor Alexandre Cortês de Menezes ◽  
Hipolito Carraro Junior ◽  
Alain Márcio Luy ◽  
Marcelo Mazza do Nascimento
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Peripheral Perfusion ◽  
Injury Analysis

Acute Kidney Injury in Children with Severe Malaria Is Common and Associated with Adverse Hospital Outcomes

2019 ◽  
Vol 66 (2) ◽  
pp. 218-225
Author(s):  
Eunice O Oshomah-Bello ◽  
Christopher I Esezobor ◽  
Adaobi U Solarin ◽  
Fidelis O Njokanma
Keyword(s):  
Acute Kidney Injury ◽  
Serum Creatinine ◽  
Severe Malaria ◽  
Complete Blood Count ◽  
Univariate Analysis ◽  
Elevated Serum ◽  
Kidney Injury ◽  
Hospital Outcomes ◽  
Elevated Serum Creatinine ◽  
Sub Saharan

Abstract Background The prevalence of acute kidney injury (AKI) in children with severe malaria in sub-Saharan African may have been underestimated. The study aimed to determine the prevalence of AKI in children with severe malaria and its association with adverse hospital outcomes. Methods At presentation, we measured complete blood count, serum bilirubin, and serum electrolytes, urea and creatinine in children with severe malaria. At 24 h after hospitalization, we repeated serum creatinine measurement. Urine passed in the first 24 h of hospitalization was also measured. We defined AKI and its severity using the Kidney Disease: Improving Global Outcome AKI guidelines. Results The study involved 244 children (53.3% males) with a median age of 3.5 (1.9–7.0) years. One hundred and forty-four (59%) children had AKI, and it reached maximum Stages 1, 2 and 3 in 56 (23%), 45 (18.4%) and 43 (17.6%) children, respectively. The majority (86.1%) with AKI had only elevated serum creatinine. Mortality increased with increasing severity of AKI on univariate analysis but weakened on multiple logistic regression. Mortality was also higher in those with both oliguria and elevated serum creatinine than in those with elevated serum creatinine only (50% vs. 4.8%, p < 0.001). Furthermore, children with AKI spent three days more in hospital than those without AKI (p < 0.001). Conclusions Acute kidney injury complicates severe malaria in 6 out of every 10 children and is commonly identified using elevated serum creatinine. It is also associated with adverse hospital outcome.

Rapid Reversal of Acute Kidney Injury and Hospital Outcomes: A Retrospective Cohort Study

2009 ◽  
Vol 53 (6) ◽  
pp. 974-981 ◽  
Author(s):  
Jianmin Tian ◽  
Fidel Barrantes ◽  
Yaw Amoateng-Adjepong ◽  
Constantine A. Manthous
Keyword(s):  
Acute Kidney Injury ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Kidney Injury ◽  
Hospital Outcomes ◽  
Rapid Reversal

scholarly journals In-hospital outcomes of self-expanding and balloon-expandable transcatheter heart valves in Germany

2021 ◽  
Author(s):  
Peter Stachon ◽  
Philip Hehn ◽  
Dennis Wolf ◽  
Timo Heidt ◽  
Vera Oettinger ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Acute Kidney Injury ◽  
Propensity Score ◽  
Hospital Mortality ◽  
Hospital Stay ◽  
Major Bleeding ◽  
Postoperative Delirium ◽  
Kidney Injury ◽  
Length Of Hospital Stay ◽  
Hospital Outcomes

Abstract Introduction The effect of valve type on outcomes in transfemoral transcatheter aortic valve replacement (TF-TAVR) has recently been subject of debate. We investigate outcomes of patients treated with balloon-expanding (BE) vs. self-expanding (SE) valves in in a cohort of all these procedures performed in Germany in 2018. Methods All patients receiving TF-TAVR with either BE (N = 9,882) or SE (N = 7,413) valves in Germany in 2018 were identified. In-hospital outcomes were analyzed for the endpoints in-hospital mortality, major bleeding, stroke, acute kidney injury, postoperative delirium, permanent pacemaker implantation, mechanical ventilation > 48 h, length of hospital stay, and reimbursement. Since patients were not randomized to the two treatment options, logistic or linear regression models were used with 22 baseline patient characteristics and center-specific variables as potential confounders. As a sensitivity analysis, the same confounding factors were taken into account using the propensity score methods (inverse probability of treatment weighting). Results Baseline characteristics differed substantially, with higher EuroSCORE (p < 0.001), age (p < 0.001) and rate of female sex (p < 0.001) in SE treated patients. After risk adjustment, no marked differences in outcomes were found for in-hospital mortality [risk adjusted odds ratio (aOR) for SE instead of BE 0.94 (96% CI 0.76;1.17), p = 0.617] major bleeding [aOR 0.91 (0.73;1.14), p = 0.400], stroke [aOR 1.13 (0.88;1.46), p = 0.347], acute kidney injury [OR 0.97 (0.85;1.10), p = 0.621], postoperative delirium [aOR 1.09 (0.96;1.24), p = 0.184], mechanical ventilation > 48 h [aOR 0.98 (0.77;1.25), p = 0.893], length of hospital stay (risk adjusted difference in days of hospitalization (SE instead of BE): − 0.05 [− 0.34;0.25], p = 0.762) and reimbursement [risk adjusted difference in reimbursement (SE instead of BE): − €72 (− €291;€147), p = 0.519)] There is, however, an increased risk of PPI for SE valves (aOR 1.27 [1.15;1.41], p < 0.001). Similar results were found after application of propensity score adjustment. Conclusions We find broadly equivalent outcomes in contemporary TF-TAVR procedures, regardless of the valve type used. Incidence of major complications is very low for both types of valve.

scholarly journals Association of Fine Particulate Matter Exposure with Acute Noncardiovascular Critical Illnesses and In-hospital Outcomes in Patients Receiving Intensive Cardiac Care

2020 ◽  
Author(s):  
Fei Chen ◽  
Qi Liu ◽  
Baotao Huang ◽  
Fangyang Huang ◽  
Yiming Li ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Particulate Matter ◽  
Respiratory Failure ◽  
Fine Particulate Matter ◽  
Kidney Injury ◽  
Cardiac Care ◽  
Short Term ◽  
Hospital Outcomes ◽  
Fine Particulate ◽  
Exposure Levels

Abstract Background: The effect of short-term exposure to fine particulate matter (PM2.5) on the incidence of acute noncardiovascular critical illnesses (ANCIs) and clinical outcomes is unknown in patients with acute cardiovascular diseases.Methods: We conducted a retrospective study in 2,337 admissions to an intensive cardiac care unit (ICCU) from June 2016 to May 2017. We used the 2-day average PM2.5 concentration before ICCU admission to estimate the individual exposure level, and patients were divided into 3 groups according to the concentration tertiles. Major ANCI was defined as the composite of acute respiratory failure, acute kidney injury, gastrointestinal hemorrhage, or sepsis. The primary endpoint was all-cause death or discharge against medical advice in extremely critical condition.Results: More than 20 percent of admissions were complicated by major ANCI, and primary endpoints occurred in 7.6% of patients during their hospitalization. The association of short-term PM2.5 exposure levels with the incidence of acute respiratory failure (adjusted OR [odds ratio] =1.31, 95%CI [confidence interval]1.12-1.54) and acute kidney injury (adjusted OR=1.20, 95%CI 1.02-1.41) showed a significant trend. Additionally, there were numerically more cases of sepsis (adjusted OR=1.21, 95%CI 0.92-1.60) and gastrointestinal hemorrhage (adjusted OR=1.29, 95%CI 0.94-1.77) in patients with higher exposure levels. After further multivariable adjustment, short-term PM2.5 exposure levels were still significantly associated with the incidence of major ANCI (adjusted OR=1.32, 95%CI 1.12-1.56), as well as with in-hospital outcomes (adjusted OR=1.52, 95%CI 1.09-2.12). Conclusion: Short-term PM2.5 exposure before ICCU admission was associated with an increased risk of incident major ANCI and worse in-hospital outcomes in patients receiving intensive cardiac care.

Outcomes of Carotid Revascularization in the Treatment of Restenosis After Prior Carotid Endarterectomy

Stroke ◽  
2021 ◽  
Author(s):  
Nadin Elsayed ◽  
Ganesh Ramakrishnan ◽  
Isaac Naazie ◽  
Sharvil Sheth ◽  
Mahmoud B. Malas
Keyword(s):  
Carotid Endarterectomy ◽  
Transient Ischemic Attack ◽  
Multivariate Logistic Regression Analysis ◽  
Hospital Outcomes ◽  
Lower Odds ◽  
Carotid Revascularization ◽  
Increased Risk ◽  
Significant Difference ◽  
Ischemic Attack ◽  
Stroke Death

Background and Purpose: Restenosis after carotid endarterectomy (CEA) is associated with an increased risk of ipsilateral stroke. The optimal procedural modality for this indication has yet to be determined. Here, we evaluate the in-hospital outcomes of transcarotid artery revascularization (TCAR), redo-CEA, and transfemoral carotid artery stenting (TFCAS) in a large contemporary cohort of patients who underwent treatment for restenosis after CEA. Methods: We performed a retrospective analysis of all patients in the vascular quality initiative database who underwent TCAR, redo-CEA, or TFCAS after ipsilateral CEA between September 2016 and April 2020. Patients with prior ipsilateral CAS were excluded from this analysis. In-hospital outcomes following TCAR versus CEA and TCAR versus TFCAS were evaluated using multivariate logistic regression analysis. Results: A total of 4425 patients were available for this analysis. There were 963 (21.8%) redo-CEA, 1786 (40.4%) TFCAS, and 1676 (37.9%) TCAR. TCAR was associated with lower odds of in-hospital stroke/death (odds ratio [OR], 0.41 [95% CI, 0.24–0.70], P =0.021), stroke (OR, 0.46 [95% CI, 0.23–0.93], P =0.03), myocardial infarction (MI; OR, 0.32 [95% CI, 0.14–0.73], P =0.007), stroke/transient ischemic attack (OR, 0.42 [95% CI, 0.24–0.74], P =0.002), and stroke/death/MI (OR, 0.41 [95% CI, 0.24–0.70], P =0.001) when compared with redo-CEA. There was no significant difference in the odds of death between the 2 groups (OR, 0.99 [95% CI, 0.28–3.5], P =0.995). TCAR was also associated with lower odds of stroke/transient ischemic attack (OR, 0.37 [95% CI, 0.18–0.74], P =0.005) when compared with TFCAS. There was no significant difference in the odds of stroke, death, MI, stroke/death, or stroke/death/MI between TCAR and TFCAS. Conclusions: TCAR was associated with significantly lower odds of in-hospital stroke, MI, stroke/transient ischemic attack, stroke/death, and stroke/death/MI when compared with redo-CEA and lower odds of in-hospital stroke/transient ischemic attack when compared with TFCAS. Additional long-term studies are warranted to establish the role of TCAR for the treatment of restenosis after CEA.

Andrographolide induced acute kidney injury: Analysis of 26 cases reported in Chinese Literature

Nephrology ◽  
2013 ◽  
Vol 19 (1) ◽  
pp. 21-26 ◽  
Author(s):  
Wu-Xing Zhang ◽  
Zhi-Min Zhang ◽  
Zhi-Qiang Zhang ◽  
Yang Wang ◽  
Wei Zhou
Keyword(s):  
Acute Kidney Injury ◽  
Chinese Literature ◽  
Kidney Injury ◽  
Injury Analysis
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