Role of the arecoline/YAP1/BMP4 pathway in promoting endothelial‐mesenchymal transition in oral submucous fibrosis

2019 ◽  
Vol 49 (4) ◽  
pp. 305-310 ◽  
Author(s):  
Mianfeng Yao ◽  
Jiang Li ◽  
Shanshan Yuan ◽  
Xilei Zhu ◽  
Zijie Hu ◽  
...  
Keyword(s):  
Oral Submucous Fibrosis ◽  
Mesenchymal Transition ◽  
Submucous Fibrosis ◽  
Endothelial Mesenchymal Transition

scholarly journals Molecular Pathogenesis of Oral Submucous Fibrosis: A Critical Appraisal

2019 ◽  
Vol 12 (04) ◽  
pp. 2027-2036 ◽  
Author(s):  
Arpita Rai ◽  
Musarrat Siddiqui ◽  
Shama Parveen ◽  
Saba Parveen ◽  
Abdur Rasheed ◽  
...  
Keyword(s):  
Critical Appraisal ◽  
Epithelial Mesenchymal Transition ◽  
Oral Submucous Fibrosis ◽  
Molecular Pathogenesis ◽  
Areca Nut ◽  
Mesenchymal Transition ◽  
Potentially Malignant ◽  
Submucous Fibrosis ◽  
Malignant Condition

Oral submucous fibrosis (OSMF) is a chronic, potentially malignant condition of the oral mucosa and the habitual chewing of areca nut is believed to be the most potent etiological factor. The role of reactive oxygen species (ROS), epithelial-mesenchymal transition (EMT) and various cytokines and growth factors has been established in recent studies. The components of areca nut particularly, arecoline, flavonoids and copper have been found to affect fibroblasts, endothelial and epithelial cells through various biological pathways which are either down-regulated or up-regulated during different stages of the disease. However, the underlying molecular pathogenesis of OSMF is still partially understood.

OI0446 Role of betamethasone in oral submucous fibrosis

2014 ◽  
Vol 117 (5) ◽  
pp. e340
Author(s):  
Kaustubh Sansare ◽  
Heena Sonawane ◽  
Neha Bansal ◽  
Freny Karjodkar
Keyword(s):  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis
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