Clinical efficacy of new aloe vera- and myrrh-based oral mucoadhesive gels in the management of minor recurrent aphthous stomatitis: a randomized, double-blind, vehicle-controlled study

2013 ◽  
Vol 43 (6) ◽  
pp. 405-409 ◽  
Author(s):  
Ghada Mansour ◽  
Soliman Ouda ◽  
Ahmed Shaker ◽  
Hossam M. Abdallah
Keyword(s):  
Clinical Efficacy ◽  
Aloe Vera ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Controlled Study ◽  
Double Blind

scholarly journals The Rapeutic Effect of Proaftol in Treatment of Recurrent Aphthous Stomatitis

PRILOZI ◽  
2014 ◽  
Vol 35 (3) ◽  
pp. 195-202
Author(s):  
Aneta Atanasovska Stojanovska ◽  
Mirjana Popovska ◽  
Ilijana Muratovska ◽  
Kristina Mitic ◽  
Emilija Stefanovska ◽  
...  
Keyword(s):  
Lesion Size ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Controlled Study ◽  
Unknown Etiology ◽  
Control Group ◽  
Subjective Feeling ◽  
Double Blind ◽  
Two Parameters ◽  
The Impact

AbstractRecurrent aphthous stomatitis (RAS) is a quite frequent, painful, ulcerative disease that affects the lining of the oral cavity and has an unknown etiology. The aim of this article is to examine the impact of the medication proaftol on epithelization speed and severity of pain in patients with RAS. In this randomized, double-blind, placebo-controlled study respondents were divided into two groups where one group was treated with proaftol spray and the other with a placebo. Aphthae considered for treatment had a diameter of 5-6 mm. The participants were given instruction on the use of the spray, two sprayings on the place of the aphtae 3-4 times a day. We examined two parameters in the symptomatology of RAS-lesion size (mm) and pain intensity (noted on four subjective levels: 0-no pain, 1-discomfort, 2-moderate pain, 3-severe pain). These parameters were noted on the baseline, the third, the fifth and the eighth days of examination.Results: A significant faster reduction of the dimension of aphthous ulcers in patients treated with proaftol 3rd day p < 0.001, 5th day p < 0.0006, 8th day full epithelization in the control group. The magnitude of pain in the experimental compared with the control group on 3rd, 5th and 8th day was also significantly reduced: p < 0.0001, p < 0.007, p < 0.007 respectively.Conclusion: The use of proaftol positively influences the rate of epithelization and reduction of subjective feeling of pain in patients with RAS. The action of propolis should be the goal of studies with a larger number of subjects.

Results of Double-Blind Placebo-Controlled Challenge with Nickel Salts in Patients Affected by Recurrent Aphthous Stomatitis

2003 ◽  
Vol 131 (4) ◽  
pp. 296-300 ◽  
Author(s):  
M.L. Pacor ◽  
G. Di Lorenzo ◽  
N. Martinelli ◽  
G. Lombardo ◽  
A. Di Gregoli ◽  
...  
Keyword(s):  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Double Blind ◽  
Double Blind Placebo

scholarly journals Effect of 0.5% Chitosan mouthwash on recurrent aphthous stomatitis: a randomized double-blind crossover clinical trial

10.19082/6912 ◽  
2018 ◽  
Vol 10 (6) ◽  
pp. 6912-6919 ◽  
Author(s):  
Fatemeh Rahmani ◽  
Ali Akbar Moghadamnia ◽  
Sohrab Kazemi ◽  
Atena Shirzad ◽  
Mina Motallebnejad
Keyword(s):  
Clinical Trial ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Double Blind
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