scholarly journals A Verbal Fluency Task‐Based Brain Activation fMRI Study in Patients with Crohn's Disease in Remission

2019 ◽  
Vol 29 (5) ◽  
pp. 630-639 ◽  
Author(s):  
Veena A. Nair ◽  
Keith Dodd ◽  
Shruti Rajan ◽  
Anu Santhanubosu ◽  
Poonam Beniwal‐Patel ◽  
...  
2016 ◽  
Vol 74 (2) ◽  
pp. 69-77 ◽  
Author(s):  
Masahiro Takamura ◽  
Yasumasa Okamoto ◽  
Go Okada ◽  
Shigeru Toki ◽  
Tetsuya Yamamoto ◽  
...  

NeuroImage ◽  
1998 ◽  
Vol 7 (4) ◽  
pp. S134
Author(s):  
K. Hugdahl ◽  
A. Lundervold ◽  
V. Hadziavdie ◽  
L. Ersland ◽  
A.I. Smievoll ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Yilei Xiang ◽  
Yuan Li ◽  
Chang Shu ◽  
Zhongchun Liu ◽  
Huiling Wang ◽  
...  

Background: Cognitive dysfunction is a common clinical feature of mental disorders. A number of functional near-infrared spectroscopy (fNIRS) studies have shown reduced prefrontal activation during the verbal fluency task (VFT) in schizophrenia (SZ) and major depressive disorder (MDD). However, no studies have examined and compared the brain activation patterns during the Tower of London (TOL), which is another classic, high-sensitivity executive function testing tool, in these two serious mental disorders. This study aimed to assess the characteristics of brain activation during the two different cognitive tasks in SZ and MDD patients.Methods: This study recruited 30 patients with SZ, 30 patients with MDD, and 30 demographically matched healthy controls (HCs). The hemodynamic changes of the prefrontal cortex (PFC) were measured using 32-channel fNIRS during performance of the TOL task and VFT task.Results: SZ patients showed poorer VFT performance than MDD patients and HCs, and the two patient groups showed poorer TOL performance than HCs. Compared to HCs, both of the patient groups exhibited a significant decreased activation in the extensive PFC. Particularly in certain channels in the dorsolateral PFC (DLPFC), SZ patients exhibited significantly decreased hemodynamic changes than the MDD patients.Conclusions: Patients with SZ and MDD have different levels of impairment in different cognitive domains and different patterns of brain activation during the two cognitive tasks. Further research is needed to determine the use of fNIRS for clinical evaluation and diagnosis.


2021 ◽  
pp. 174702182110341
Author(s):  
Maryll Fournet ◽  
Michaela Pernon ◽  
Sabina Catalano Chiuvé ◽  
Ursula Lopez ◽  
Marina Laganaro

There is a general agreement that speaking requires attention at least for conceptual and lexical processes of utterance production. However, conflicting results have been obtained with dual-task paradigms using either repetition tasks or more generally tasks involving limited loading of lexical selection. This study aimed to investigate whether post-lexical processes recruit attentional resources. We used a new dual-task paradigm in a set of experiments where a continuous verbal production task involved either high or low demand on lexical selection processes. Experiment 1 evaluates lexical and post-lexical processes with a semantic verbal fluency task, whereas experiments 2 and 3 focus on post-lexical processes with a non-propositional speech task. In each experiment, two types of non-verbal secondary tasks were used: processing speed (simple manual reaction times) or inhibition (Go/No-go). In Experiment 1, a dual-task cost was observed on the semantic verbal fluency task and each non-verbal task. In Experiment 2, a dual-task cost appeared on the non-verbal tasks but not on the speech task. The same paradigm was used with older adults (Experiment 3), as increased effort in post-lexical processes has been associated with ageing. For older adults, a dual-task cost was also observed on the non-propositional verbal task when speech was produced with the inhibition non-verbal task. The results suggest an attentional cost on post-lexical processes and strategic effects in the resolution of the dual-task.


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