HrQoL in hair loss‐affected patients with alopecia areata, androgenetic alopecia and telogen effluvium: the role of personality traits and psychosocial anxiety

2018 ◽  
Vol 33 (3) ◽  
pp. 608-611 ◽  
Author(s):  
P.M. Russo ◽  
E. Fino ◽  
C. Mancini ◽  
M. Mazzetti ◽  
M. Starace ◽  
...  
Keyword(s):  
Personality Traits ◽  
Hair Loss ◽  
Alopecia Areata ◽  
Androgenetic Alopecia

Disorders of Hair

2013 ◽  
Author(s):  
James Q Del Rosso
Keyword(s):  
Hair Loss ◽  
Alopecia Areata ◽  
Hair Growth ◽  
Growth Cycle ◽  
Hair Follicles ◽  
Common Type ◽  
Diagnosis And Treatment ◽  
Basic Knowledge ◽  
Androgenetic Alopecia ◽  
Broad Overview

A basic knowledge of the hair growth cycle is needed to evaluate disorders of hair growth. This chapter presents a broad overview of the physiology and evaluation of hair growth, as well as discussions of specific types of alopecia. The epidemiology, pathogenesis, diagnosis, and treatment of androgenetic alopecia, the most common type of nonscarring hair loss, are covered. Diffuse hair shedding is generalized hair loss over the entire scalp. Diagnosis and treatment of telogen effluvium, anagen arrest (anagen effluvium), and other causes of diffuse hair shedding are covered in detail. Alopecia areata, typically characterized by patchy hair loss; cicatricial alopecia, which results from permanent scarring of the hair follicles; and miscellaneous causes of hair loss are also discussed. Tables list the causes of diffuse and cicatricial alopecia, telogen effluvium, and miscellaneous chemicals and categories of drugs that can cause alopecia, as well as miscellaneous causes of hair loss. Included is an algorithm outlining the approach to diagnosing nonscarring alopecia, as well as a variety of clinical photographs. This review contains 9 highly rendered figures, 6 tables, and 42 references.

scholarly journals Clinical and histological challenge in the differential diagnosis of diffuse alopecia: female androgenetic alopecia, telogen effluvium and alopecia areata - part II

2012 ◽  
Vol 87 (6) ◽  
pp. 884-890 ◽  
Author(s):  
Betina Werner ◽  
Fabiane Mulinari-Brenner
Keyword(s):  
Differential Diagnosis ◽  
Hair Loss ◽  
Alopecia Areata ◽  
Diagnostic Approach ◽  
Androgenetic Alopecia

Diffuse alopecia is mainly caused by telogen effluvium, diffuse androgenetic alopecia (femalepattern hair loss) and diffuse alopecia areata. Differential diagnosis between the three disorders may be difficult in several occasions. In this second part of our study, chronic telogen effluvium and diffuse alopecia areata are discussed in detail, including clinical, dermoscopic and histological aspects. A flowchart presents a practical and objective differential diagnostic approach to diffuse alopecia.

Patterned Trichoteiromania in Androgenetic Alopecia

2021 ◽  
pp. 1-4
Author(s):  
Luis E. Sánchez-Dueñas ◽  
Leslie E. Rocha-Méndez ◽  
Lidia Rudnicka
Keyword(s):  
Psychiatric Disorders ◽  
Hair Loss ◽  
Alopecia Areata ◽  
Medical Literature ◽  
Androgenetic Alopecia ◽  
Distressing Condition

Trichotillomania is the most frequent reported cause of self-inflicted hair disorders, within which are included trichoteiromania, trichotemnomania, and trichocryptomania, also known as trichorrexomania. These conditions are commonly described in the context of psychiatric disorders. Nevertheless, there exists reports in otherwise healthy patients that suffer a form of no cicatricial alopecia, such as alopecia areata. We communicate 3 cases of male androgenetic alopecia with patterned miniaturization that coexisted with trichoscopic findings of trichoteiromania. The presence of brush-like ends or broom hairs is a highly suggestive feature of this entity. To the best of our knowledge, this association was not previously reported in the medical literature. The possibility of self-induced hair loss should be kept in mind during every follow-up visit in all types of alopecia, remembering that hair loss itself is already a distressing condition.

scholarly journals Early Baldness in Males and Hormonal Changes

2016 ◽  
Vol 13 (2) ◽  
pp. 362-367
Author(s):  
Baghdad Science Journal
Keyword(s):  
Immunosorbent Assay ◽  
Hair Loss ◽  
Androgenetic Alopecia ◽  
Enzyme Linked Immunosorbent Assay ◽  
Hormonal Changes ◽  
Treatment Target ◽  
Healthy Men ◽  
New Drug

Androgenetic alopecia (AGA) or baldness is a common form of hair loss, affecting men more than women .The exact causes and pathogenesis of baldness are not well understood. A search for new drug is still needed. This study aims to evaluate the role of gonadotropins hormones in hair loss in males and its possibility to be used as treatment target. A total of 78 volunteers 43 with baldness and 35 healthy men were participated in this study. Their age ranged between (20-49) years, the studied groups were divided into two categories: firstly according to age (group1: 20-29 year), (group2: 30-39 year),and (group3: 40-49 year).Secondly according to baldness degree. LH and FSH were measured by using Enzyme Linked Immunosorbent Assay (ELISA) kits. The results showed a significant decrease (p

scholarly journals Managing patterned hair loss – a hair raising task!

2021 ◽  
Vol 1 ◽  
pp. 55
Author(s):  
Aseem Sharma ◽  
Manasi Shirolikar ◽  
Madhulika Mhatre
Keyword(s):  
Hair Loss ◽  
Clinical Presentation ◽  
Short Review ◽  
Population Based ◽  
Androgenetic Alopecia ◽  
Psychosocial Burden ◽  
Weighted Averages ◽  
Female Pattern Hair Loss ◽  
Topical Minoxidil

Diffuse alopecia wields a significant psychosocial burden by virtue of its clinical presentation and visibility. Patterned alopecia is an umbrella term with the focus point being androgen-mediated alopecias - androgenetic alopecia/male pattern baldness/male androgenetic alopecia and female pattern hair loss/female androgenetic alopecia, both of which have a genetic susceptibility that alters the follicular sensitivity to circulating androgens. Diffuse alopecia affects nearly half the population based on weighted averages. It may present with hair shedding and hair thinning (miniaturization) or a combination. With the female variant, the role of androgens is not fully delineated; hence, the term female pattern hair loss which has replaced prior nomenclature. Managing patterned hair loss has seen a sea change in the last decade, moving well beyond the FDA-approved modalities - topical minoxidil and oral finasteride. Through this short review, the authors have attempted to condense existing information into a ready reference.

Canities Subita after Extreme Trauma Showing Positive Staining for Anti-PD-L1 Antibodies: A New Clue into Etiopathogenesis?

2021 ◽  
Vol 8 (1) ◽  
pp. 65-69
Author(s):  
Francisco J. Navarro-Triviño ◽  
Ricardo Ruiz-Villaverde ◽  
Francisco Manuel Ramos-Pleguezuelos ◽  
Sergio Vañó-Galván
Keyword(s):  
Hair Loss ◽  
Alopecia Areata ◽  
Inflammatory Infiltrate ◽  
Hair Color ◽  
Histopathological Study ◽  
Positive Staining ◽  
Immune Mediated ◽  
History Of ◽  
Salt And Pepper

Canities subita has been considered by some authors an acute episode of diffuse alopecia areata in which the sudden whitening is caused by the preferential loss of pigmented hair in this immune-mediated disorder. Clinically, the “salt and pepper” pattern of hair color is the most frequent manifestation of canities subita. However, the exact physiopathology of canities subita is not completely understood. A 69-year-old Caucasian man was referred for the sudden and asymptomatic whitening of the hair on the scalp and eyebrows, without an associated hair loss. The trigger was the death of his brother. Hair whitening appeared 24 h after the event. He reported a history of alopecia areata in plaques on the scalp, with spontaneous complete resolution in 2006. The physical examination showed full whitening hair on the scalp and eyebrows. Eyelashes were not affected. The pull test was negative, and the patient denied a significant hair loss in the last days. The histopathological study showed several follicle-sebaceous structures in the anagen, and one of them (inset) with a transforming hair bulb. The anterior bulb was surrounded by a lymphocytic inflammatory infiltrate in an advanced stage of transformation to the catagen and incipient scar changes. Immunohistochemistry staining showed a positive anti-PD-L1 antibody expressed in the inflammatory infiltrate. Based on the clinical and histological findings, a diagnosis of canities subita was made. The histopathological study showed a positive staining for anti-PD-L1 antibodies, supporting the role of the immune system in the development of this phenomenon. The interaction between melanogenesis and the lymphocytes warrants further research.

Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Mahira Hamdy El Sayed ◽  
Marwa Yassin Soltan ◽  
Ahmed Sadek ◽  
Mohamed Abo Shabana Hussein Mohamed
Keyword(s):  
Side Effects ◽  
Hair Loss ◽  
Early Onset ◽  
University Hospital ◽  
Androgenetic Alopecia ◽  
Control Group ◽  
Terminal Hair ◽  
Reactive Oxygen Species Scavenger ◽  
Male Pattern

Abstract Background Androgenetic alopecia (AGA), the most common form of hair loss in men, involves the progressive loss of visible pigmented terminal hair on the scalp in response to circulating androgens. AGA is an autosomal disorder which begins in puberty in genetically predisposed individuals. Aim of the Work To study the effectiveness and safety of the reactive oxygen species scavenger Nacetyl-cysteine (NAC) as a single therapy and in combination with the topically applied minoxidil for treatment of the early-onset androgenetic alopecia in men. Patients and Methods The present study included 100 patients with male pattern hair loss whose age ranged from 18 to 30 years old, recruited from dermatology clinics in Ain Shams University Hospital and Kafr El Sheik University Hospital. Results Overall, all treatments could improve significantly some of the trichoscopic parameters as compared to the control group who did not receive any treatment. The number of terminal hair count increased and the vellus hair count decreased in response to either of treatments; minoxidil, NAC, or both as compared to control. These changes were noticed at both the vertex and frontotemporal sites. The treatment was generally tolerable and the side effects encountered did not necessitate stoppage of the treatment course. Conclusion On the basis of the findings of current study we can conclude that, the role of trichoscopy in increasing the accuracy for diagnosing hair disorders as well as to detect response or failure to treatment, N-acetylcysteine (NAC) improved significantly most of the trichoscopic features of AGA and it was was generally tolerable and the side effects encountered did not necessitate stoppage of the treatment course.

scholarly journals A Study of Serum Ferritin Level in Female Patient with Alopecia

2018 ◽  
Vol 14 (2) ◽  
pp. 116-120
Author(s):  
Manish Pradhan ◽  
Dipa Rai ◽  
Sagar Paudel
Keyword(s):  
Serum Ferritin ◽  
Hair Loss ◽  
Alopecia Areata ◽  
Mean Value ◽  
Androgenetic Alopecia ◽  
Iron Store ◽  
Body Iron ◽  
Body Iron Store ◽  
Significant Difference ◽  
Total Body

 ABSTRACTIntroduction: Total body iron store is an integral factor in the development of hair follicle. Numerous studies have been done seeking for the relationship between body iron store and various forms of chronic diffuse hair loss, with relatively contradictory findings in various reports in these studies. The main objective of this study is to find out if there is any association between total body iron store and various types of chronic diffuse hair loss in females in reproductive age.Materials and Methods: This is a hospital based case control study conducted in Nobel Medical College and Teaching Hospital, Biratnagar, Nepal. Sixty female patients of age group 15-50 years with chronic diffuse hair loss with equal number of age- and sex- matched controls were studied. Both of the study groups were evaluated for various parameters of iron status. Results: The mean value of serum ferritin in cases was significantly lower as compared to controls (p=0.018). Patients with alopecia areata (p=0.008) and androgenetic alopecia (p=0.021) had significantly lower serum ferritin, whereas there was no statistically significant difference in telogen effluvium and controls (p=0.857).The mean value of hemoglobin, hematocrit and mean corpuscular hemoglobin was found to be significantly lower in alopecia areata and androgenetic alopecia. However, there was no statistically significant difference in RBC indices of patients of telogen effluvium and controls.Conclusion: Diffuse chronic hair loss shows definite association with serum ferritin and various RBC indices in female of reproductive age group. Alopecia areata and androgenetic alopecia show major association with total body iron stores. Keywords: alopecia areata; androgenetic alopecia; serum ferritin; telogen effluvium.    

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