A prospective right-left comparative study to evaluate the efficacy and tolerability of combination of NB-UVB and topical bimatoprost 0.03% eye drops versus NB-UVB given alone in patients of vitiligo vulgaris

2018 ◽  
Vol 32 (8) ◽  
pp. e330-e331 ◽  
Author(s):  
S. Sharma ◽  
D. Parsad ◽  
R. Bhattacharjee ◽  
S.K. Muthu
Keyword(s):  
Comparative Study ◽  
Eye Drops

scholarly journals A comparative study of efficacy of chloroquine phosphate 0.03% and sodium carboxymethylcellulose 1% in dry eye

2021 ◽  
Vol 7 (2) ◽  
pp. 302-307
Author(s):  
Vandana Sharma ◽  
Parag Tyagi ◽  
J P Chugh ◽  
R S Chauhan ◽  
Ashok Rathi
Keyword(s):  
Drug Therapy ◽  
Comparative Study ◽  
Dry Eye ◽  
Ocular Surface ◽  
Tear Film ◽  
Eye Drops ◽  
Onset Of Action ◽  
Dry Eyes ◽  
Ocular Symptoms ◽  
Group 2

Dry eye disease (DED) is a multifactorial disease of the tear film which leads to ocular discomfort, visual disturbances and damage to ocular surface. The objective of treatment of DED has now shifted from managemnt of ocular symptoms and patient relief to attainment of normal physiological composition of the tear film.Aim of this study was to compare the efficacy of chloroquine phosphate 0.03% (CQP) eye drops with sodium carboxymethyl cellulose 1% (CMC) eye drops in the management of DED. A single blind, prospective and comparative study including 100 patients of dry eyes was planned. The patients were randomly divided into two groups, each comprising of 50 patients. Group-1 patients were given CMC 1% eye drops 4 times a day for 12 weeks and Group-2 patients were given CQP 0.03% eye drops as the treatment modality 2 times a day for 12 weeks. The efficacy of both the drugs was compared and evaluated statistically. The study showed that both CQP and CMC eye drops are effective in treating DED, although faster onset of action was observed with CQP on ocular surface staining tests and Schirmer’s test. Also, it was noted that patients with severe DED showed least improvement in both the groups suggesting that mono-drug therapy is least effective in treatment of severe DED and multi drug therapy should be used early in treatment of severe DED.

scholarly journals Autologous serum eye drops diluted with sodium hyaluronate: clinical and experimental comparative study

2013 ◽  
Vol 92 (1) ◽  
pp. e22-e29 ◽  
Author(s):  
José S. López-García ◽  
Isabel García-Lozano ◽  
Luis Rivas ◽  
Nuria Ramírez ◽  
Rafaela Raposo ◽  
...  
Keyword(s):  
Comparative Study ◽  
Sodium Hyaluronate ◽  
Autologous Serum ◽  
Eye Drops ◽  
Serum Eye Drops

scholarly journals Comparative Study of Epithelial and Fibroblastic Cell Lines as an Alternative Cytotoxicity Test to the Draize Method

2000 ◽  
Vol 83 (3) ◽  
pp. 665-668
Author(s):  
Terezinha De J A Pinto ◽  
Janice C De Azevedo ◽  
Áurea S Cruz
Keyword(s):  
Comparative Study ◽  
Cell Lines ◽  
Eye Drops ◽  
Cytotoxicity Test ◽  
Excellent Correlation ◽  
Fibroblastic Cell ◽  
L929 Cells ◽  
Considerable Advantage ◽  
Draize Test ◽  
Adults And Children

Abstract Several methods are being used with considerable advantage as alterantives to the Draize test, although some technical difficulties still persist. This work compared the sensitivity of HeLa and NCTC L 929 cells to evaluate the cytotoxicity of shampoos used by adults and children (undiluted and diluted to 25, 5, 1, and 0.1%), and eye drops and their containers and surfactants (diluted to 30, 10, 1, and 0.1%). Nondiluted adult shampoos and their 25 and 5% dilutions were cytoxic for both cell lines. When diluted to 1%, only one of the shampoos was noncytotoxic, whereas among those diluted to 0.1%, only one was cytotoxic. Children's shampoos were cytotoxic when not diluted or diluted to 25%. From those diluted to 5%, only one was noncytotoxic for both cell lines. The cytotoxic tests showed that the eye drops and their containers were noncytotoxic. Surfactants were cytotoxic when diluted to 30 and 10% and noncytotoxic when diluted to 1 and 0.1%. An excellent correlation (r = 0.95) was demonstrated between the sensitivity of the HeLa and NCTC L929 cells in the evaluation of cytotoxicity reactions.

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