scholarly journals Piloplex, a new long-acting pilocarpine polymer salt. B: Comparative study of the visual effects of pilocarpine and Piloplex eye drops.

1979 ◽  
Vol 63 (1) ◽  
pp. 48-51 ◽  
Author(s):  
Z Mazor ◽  
U Ticho ◽  
U Rehany ◽  
L Rose
Keyword(s):  
Comparative Study ◽  
Eye Drops ◽  
Visual Effects ◽  
Long Acting

Comparative study of extended release albuterol sulfate and long-acting inhaled salmeterol xinafoate in the treatment of nocturnal asthma

1999 ◽  
Vol 83 (2) ◽  
pp. 121-126 ◽  
Author(s):  
Richard J. Martin ◽  
Monica Kraft ◽  
Wilfred N. Beaucher ◽  
Frederic Kiechel ◽  
James L. Sublett ◽  
...  
Keyword(s):  
Comparative Study ◽  
Extended Release ◽  
Nocturnal Asthma ◽  
Salmeterol Xinafoate ◽  
Albuterol Sulfate ◽  
Long Acting

Psychopathology and global functioning in schizophrenic patients on depot antypsychotics and long-acting injectable risperidone: A six month comparative study

2007 ◽  
Vol 22 ◽  
pp. S116
Author(s):  
A. Intxausti ◽  
A.L. Morera ◽  
C.C. González-Hernández ◽  
D. Alonso-Diaz ◽  
N. González-Brito ◽  
...  
Keyword(s):  
Comparative Study ◽  
Global Functioning ◽  
Schizophrenic Patients ◽  
Long Acting

Return to ovulation following the use of long-acting injectable contraceptives: A comparative study

Contraception ◽  
1985 ◽  
Vol 31 (4) ◽  
pp. 361-366 ◽  
Author(s):  
J. Garza-Flores ◽  
S. Cardenas ◽  
V. Rodríguez ◽  
M.C. Cravioto ◽  
V. Diaz-Sanchez ◽  
...  
Keyword(s):  
Comparative Study ◽  
Long Acting ◽  
Injectable Contraceptives

scholarly journals Comparative Study on Pharmacokinetics of Four Long-Acting Injectable Formulations of Enrofloxacin in Pigs

2021 ◽  
Vol 7 ◽  
Author(s):  
Salah Uddin Ahmad ◽  
Jichao Sun ◽  
Fusheng Cheng ◽  
Bing Li ◽  
Safia Arbab ◽  
...  
Keyword(s):  
Comparative Study ◽  
High Performance ◽  
Pasteurella Multocida ◽  
Plasma Concentrations ◽  
Pharmacokinetic Parameters ◽  
Maximum Plasma ◽  
Reference Formulation ◽  
Time Curve ◽  
Drug Concentrations ◽  
Long Acting

A comparative study on pharmacokinetics of four long-acting enrofloxacin injectable formulations was investigated in 36 healthy pigs after intramuscular injection according to the recommended single dose @ 2.5 mg/kg body weight. The drug concentrations in the plasma were computed using high-performance liquid chromatography (HPLC) with fluorescence detection. WinNonLin5.2.1 software was used to analyze the experimental data and compared it under one-way ANOVA using SPSS software with a 95% confidence interval (CI). The main pharmacokinetic parameters, that is, the maximum plasma concentrations (Cmax), the time to maximum concentration (Tmax), area under the time curve concentration (AUCall) and Terminal half-life (T1/2) were 733.84 ± 129.87, 917.00 ± 240.13, 694.84 ± 163.49, 621.98 ± 227.25 ng/ml, 2.19 ± 0.0.66, 1.50 ± 0.37, 2.89 ± 0.24, 0.34 ± 0.13 h, 7754.43 ± 2887.16, 8084.11 ± 1543.98, 7369.42 ± 2334.99, 4194.10 ± 1186.62 ng h/ml, 10.48 ± 2.72, 10.37 ± 2.38, 10.20 ± 2.81, and 10.61 ± 0.86 h for 10% enrofloxacin (Alkali), 20% enrofloxacin (Acidic), Yangkang and control drug Nuokang® respectively. There were significant differences among Cmax, Tmax, and AUCall of three formulations compare with that of the reference formulation. No significant differences were observed among the T1/2 for tested formulations compare with the reference formulation. The pharmacokinetic parameters showed that the tested formulations were somewhat better compared to the reference one. The calculated PK/PD indices were effective for bacteria such as Actinobacillus pleuropneumoniae and Pasteurella multocida with values higher than the cut-off points (Cmax/MIC90≥10–12 and AUC/MIC90 ≥ 125). However, they were not effective against bacteria like Haemophilus parasuis, Streptococcus suis, E. coli, and Bordetella bronchiseptica where lower values were obtained.

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