scholarly journals Autologous serum eye drops diluted with sodium hyaluronate: clinical and experimental comparative study

2013 ◽  
Vol 92 (1) ◽  
pp. e22-e29 ◽  
Author(s):  
José S. López-García ◽  
Isabel García-Lozano ◽  
Luis Rivas ◽  
Nuria Ramírez ◽  
Rafaela Raposo ◽  
...  
Keyword(s):  
Comparative Study ◽  
Sodium Hyaluronate ◽  
Autologous Serum ◽  
Eye Drops ◽  
Serum Eye Drops

scholarly journals Autologous serum eye drops for dry eye

2013 ◽  
Author(s):  
Qing Pan ◽  
Adla Angelina ◽  
Andrea Zambrano ◽  
Michael Marrone ◽  
Walter J Stark ◽  
...  
Keyword(s):  
Dry Eye ◽  
Autologous Serum ◽  
Eye Drops ◽  
Serum Eye Drops

Treatment of persistent epithelial defects with single-dose autologous serum eye drops

2021 ◽  
pp. 112067212110483
Author(s):  
Selma Özbek-Uzman ◽  
Züleyha Yalnız-Akkaya ◽  
Evin Şingar Özdemir ◽  
Ayşe Burcu
Keyword(s):  
Single Dose ◽  
Healing Time ◽  
Autologous Serum ◽  
Eye Drops ◽  
Artificial Tears ◽  
Duration Of Treatment ◽  
The Mean ◽  
Preservative Free ◽  
Serum Eye Drops

Purpose: We aimed to investigate the efficacy and safety of single-dose autologous serum eye drops (ASEDs) for treatment of persistent corneal epithelial defects (PEDs). Methods: About 34 eyes of 26 patients treated from March 2016 to May 2020 with a single dose of ASEDs for PEDs that did not respond to conventional treatment were retrospectively evaluated. Patient demographics, predisposing factors, size, and duration of the PED, duration of treatment, and dosage of ASEDs, PED healing time, success rate of the ASED treatment, and follow-up time after the onset of ASED treatment were recorded. Autologous serum eye drops (20%) were prepared by diluting the serum with preservative-free artificial tears in single-dose vials. Vials were stored at −20°C and used daily after dissolving. Results: The mean patient age was 47.0 ± 18.5 years, and 13 (50%) of the patients were male. The most common indication for ASEDs was PED after keratoplasty. The mean duration of ASED treatment was 8.5 ± 6.3 months, and mean follow-up time was 22.8 ± 12.2 months. Autologous serum eye drop treatment was effective in 25 (73.5%) eyes and partially effective in 5 (14.7%) eyes. None of the eyes displayed complications related to the treatment. Conclusion: In patients with PED for whom conservative treatment is insufficient, ASEDs prepared by dilution with preservative-free artificial tears in single-dose vials and administered based on the daily use principle appear to be effective and safe.

Effect of Autologous Serum Eye Drops on Corneal Haze After Corneal Crosslinking

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Ana M. Roldan ◽  
Sofia De Arrigunaga ◽  
Joseph B. Ciolino
Keyword(s):  
Autologous Serum ◽  
Eye Drops ◽  
Corneal Crosslinking ◽  
Corneal Haze ◽  
Serum Eye Drops

PP-034 Use of autologous serum eye drops prepared in a hospital pharmacy service

2016 ◽  
Vol 23 (Suppl 1) ◽  
pp. A209.1-A209
Author(s):  
B Feal Cortizas ◽  
M Garcia Queiruga ◽  
C Mondelo Garcia ◽  
MI Martin Herranz
Keyword(s):  
Hospital Pharmacy ◽  
Pharmacy Service ◽  
Autologous Serum ◽  
Eye Drops ◽  
Serum Eye Drops

Application of autologous serum eye drops after pterygium surgery: a prospective study

2018 ◽  
Vol 256 (10) ◽  
pp. 1939-1943 ◽  
Author(s):  
Sabahattin Sul ◽  
Safak Korkmaz ◽  
Goksu Alacamli ◽  
Pelin Ozyol ◽  
Erhan Ozyol
Keyword(s):  
Prospective Study ◽  
Autologous Serum ◽  
Eye Drops ◽  
Pterygium Surgery ◽  
A Prospective Study ◽  
Serum Eye Drops

scholarly journals Evaluation of the Efficacy of 50% Autologous Serum Eye Drops in Different Ocular Surface Pathologies

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Francesco Semeraro ◽  
Eliana Forbice ◽  
Osvaldo Braga ◽  
Alessandro Bova ◽  
Attilio Di Salvatore ◽  
...  
Keyword(s):  
Ocular Surface ◽  
Conventional Therapy ◽  
Keratoconjunctivitis Sicca ◽  
Signs And Symptoms ◽  
Autologous Serum ◽  
Eye Drops ◽  
Blurred Vision ◽  
Group 2 ◽  
Serum Eye Drops ◽  
Group 1

Purpose. This study evaluated the efficacy of 50% autologous serum eye drops in ocular surface diseases not improved by conventional therapy.Methods. We analyzed two groups: (1) acute eye pathologies (e.g., chemical burns) and (2) chronic eye pathologies (e.g., recurrent corneal erosion, neurotropic keratitis, and keratoconjunctivitis sicca). The patients were treated for surface instability after conventional therapy. The patients received therapy 5 times a day until stabilization of the framework; they then reduced therapy to 3 times a day for at least 3 months. We analyzed the best corrected visual acuity, epithelial defects, inflammation, corneal opacity, and corneal neovascularization. We also analyzed symptoms such as tearing, burning, sense of foreign body or sand, photophobia, blurred vision, and difficulty opening the eyelids.Results. We enrolled 15 eyes in group 1 and 11 eyes in group 2. The average therapy period was 16 ± 5.86 weeks in group 1 and 30.54 ± 20.33 weeks in group 2. The epithelial defects all resolved. Signs and symptoms improved in both groups. In group 2, the defect recurred after the suspension of therapy in 2 (18%) patients; in group 1, no defects recurred.Conclusions. Autologous serum eye drops effectively stabilize and improve signs and symptoms in eyes previously treated with conventional therapy.

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