Evaluation of oral isotretinoin effects on hearing system in patients with acne vulgaris: Reversible or not?

2020 ◽  
Author(s):  
Funda Kemeriz ◽  
Serkan Kayabaşı ◽  
Bengü Cevirgen Cemil ◽  
Ömer Hızlı
Keyword(s):  
Acne Vulgaris ◽  
Oral Isotretinoin ◽  
Hearing System

scholarly journals Sacroiliitis after use of oral isotretinoin - association with acne fulminans or adverse effect?

2013 ◽  
Vol 88 (6 suppl 1) ◽  
pp. 193-196 ◽  
Author(s):  
Ariane Silva Bastos Geller ◽  
Roberta Ferreira Nazareth Alagia
Keyword(s):  
Adverse Effect ◽  
Back Pain ◽  
Acne Vulgaris ◽  
Severe Form ◽  
Sacroiliac Joints ◽  
Male Adolescents ◽  
Acne Fulminans ◽  
Oral Isotretinoin ◽  
Inflammation Resolution ◽  
Retinoid Treatment

Acne fulminans is a rare and severe form of acne that may evolve from acne vulgaris, especially in male adolescents, or occur as an adverse effect of oral isotretinoin. Arthritis is a serious clinical manifestation when the musculoskeletal system is compromised by AF and has been reported as a rare adverse effect of isotretinoin. Involvement of the sacroiliac joints occurs in 21% of acne fulminans cases. We present the case of a 18-year-old male patient in whom acne fulminans evolved from acne vulgaris grade IV and after inflammation resolution started treatment with oral isotretinoin. Within a 30-day period of retinoid treatment he presented with back pain followed by rapid, progressive inability to deambulate.

scholarly journals The efficacy of 5% dapsone gel plus oral isotretinoin versus oral isotretinoin alone in acne vulgaris: A randomized double-blind study

2014 ◽  
Vol 3 (1) ◽  
pp. 177 ◽  
Author(s):  
Mehrdad Rakhshanpour ◽  
Bahareh Abtahi-Naeini ◽  
MohammadAli Nilforoushzadeh ◽  
Gita Faghihi
Keyword(s):  
Acne Vulgaris ◽  
Blind Study ◽  
Double Blind Study ◽  
Double Blind ◽  
Oral Isotretinoin

scholarly journals Altered Gene Expression in Acne Vulgaris Patients Treated by Oral Isotretinoin: A Preliminary Study

2020 ◽  
Vol Volume 13 ◽  
pp. 385-395
Author(s):  
Yuchen Jiang ◽  
Haiyan Chen ◽  
Le Han ◽  
Xiaoyuan Xie ◽  
Yue Zheng ◽  
...  
Keyword(s):  
Gene Expression ◽  
Acne Vulgaris ◽  
Altered Gene Expression ◽  
Oral Isotretinoin ◽  
Preliminary Study ◽  
Altered Gene

scholarly journals Evidence on acne therapy

2013 ◽  
Vol 131 (3) ◽  
pp. 193-197 ◽  
Author(s):  
Caroline Sousa Costa ◽  
Edileia Bagatin
Keyword(s):  
Bacterial Resistance ◽  
Scientific Evidence ◽  
Acne Vulgaris ◽  
Optimum Dose ◽  
Oral Antibiotics ◽  
Duration Of Treatment ◽  
Medical Databases ◽  
Systemic Treatments ◽  
Acne Therapy ◽  
Oral Isotretinoin

Among the current treatments available for acne vulgaris, many widely practiced options lack support from studies at the best level of scientific evidence. The aim of this narrative review was to present the very latest information on topical and systemic treatments for acne vulgaris. Information from systematic reviews and well-designed clinical trials, obtained through a systematic search of the major medical databases, is emphasized. There are important issues regarding the clinical management of acne that still lack consistent grounding in scientific evidence. Among these are the optimum dose and duration of treatment with oral antibiotics that can be given without inducing bacterial resistance, and the safety of oral isotretinoin.

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