Letter to the editor regarding article “El‐Hamd MA, El Taieb MA, Ibrahim HM, Aly SS. Vitamin D levels in acne vulgaris patients treated with oral isotretinoin. J Cosmet Dermatol 2019;18(1):16‐20”

2019 ◽  
Vol 19 (3) ◽  
pp. 763-763
Author(s):  
Esra Pancar Yüksel ◽  
Fatma Aydın
2018 ◽  
Vol 18 (1) ◽  
pp. 16-20 ◽  
Author(s):  
Mohammed Abu El‐Hamd ◽  
Moustafa A El Taieb ◽  
Hassan M Ibrahim ◽  
Sanaa S Aly

Author(s):  
DYAH SAPTARINI ◽  
FIASTUTI WITJAKSONO ◽  
IRMA BERNADETTE S. SITOHANG

Objective: Approximately 9.4% of the world population is affected by acne during adolescence. Several previous studies have shown a significant relationship between acne vulgaris (AV) and serum vitamin D levels. The purpose of this study was to determine the correlation between AV and serum vitamin D levels in adolescents. Methods: This cross-sectional study included 60 healthy students with AV aged 15-18 y from three high schools in Depok, which were selected via simple random selection, and the selection of participants was based on consecutive sampling selection after screening with the inclusion criteria. Serum vitamin D levels were evaluated using a direct Chemiluminescence immunoassay (CLIA) method. The lesions of AV were counted by a dermatologist. Dietary vitamin D and fat intake were assessed using a semiquantitative Food Frequency Questionnaire and 24-hour dietary recall. The data were processed using SPSS Statistics 20.0 and analyzed using Pearson or Spearman correlation tests. Results: The mean serum vitamin D level was 17.29±6.77 ng/ml. The mean number of non-inflammatory lesions was 20.5±12.08, and the median number of inflammatory lesions was 6 (range 0-28). The correlation between the number of non-inflammatory lesion and serum vitamin D levels was r = 0.25 (p = 0.052) and the correlation between the number of inflammatory lesions and serum vitamin D levels was r = 0.047 (p = 0.72). Conclusion: Serum vitamin D levels are not significantly correlated with AV despite whether the lesions are inflammatory or non-inflammatory.


2017 ◽  
Vol 2 (44) ◽  
pp. 33-35 ◽  
Author(s):  
Gülbahar Saraç ◽  
Tuba Tülay Koca ◽  
Serpil Şener ◽  
Hülya Cenk

2021 ◽  
Vol 15 (1) ◽  
pp. 11-15
Author(s):  
Mohammed Al-Dhubaibi ◽  
Ghadah Alhetheli ◽  
Adel Alsenaid ◽  
Ahmed Abd Elneam

Background: Acne vulgaris is a common chronic inflammatory skin disorder of pilosebaceous units. Isotretinoin (13-cis retinoic acid) is the most effective multifunctional treatment for moderate-to-severe and nodulocystic acne. Vitamin D plays a role in the immune system, and its deficiency might contribute to the pathogenesis of acne. Objective: To investigate whether isotretinoin improves serum 25-hydroxyvitamin D levels in acne vulgaris patients. Methods: This prospective cohort study included 68 patients with acne vulgaris. Lipid profiles, liver function tests, and serum 25-hydroxyvitamin D [25 (OH) D] levels were measured at baseline and three months after starting isotretinoin treatment. Results: There was a significant increase in serum vitamin D levels three months after starting isotretinoin treatment in mild acne patients (P=0.0003). Conclusion: Vitamin D levels are altered in acne vulgaris. Isotretinoin therapy is associated with an increase in vitamin D levels, which was statistically significant in mild acne patients. Considering the role of vitamin D in acne, effective treatment with isotretinoin might highlight vitamin D as a possible target for acne therapy or as a biomarker for disease activity and remission.


2020 ◽  
Vol 33 (3) ◽  
Author(s):  
Funda Kemeriz ◽  
Sibel Çiğdem Tuncer ◽  
Emine Müge Acar ◽  
Burcu Tuğrul

2012 ◽  
Vol 27 (1) ◽  
pp. 49-49
Author(s):  
Damián H Zanette

In a recent Letter to the Editor, Grant and Pilz propose the hypothesis of a contribution of very low serum 25-hydroxyvitamin D levels to provoke Wolfgang Amadeus Mozart’s death. Mozart died on the 5th of December, 1791, aged 35, probably due to an infection which, very likely, had low vitamin D levels as an important risk factor. According to Grant and Pilz, the lack of vitamin D is to be attributed, in the case of Mozart’s, to insufficient exposure to sunlight, because he “did much of his composing at night, so would have slept during much of the day.” Historical evidence, however, disproves the nocturnal habits of the Austrian composer.


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