The frequency and types of epilepsy in children with cerebral palsy and white matter injury

2016 ◽  
Vol 58 ◽  
pp. 31-31
PEDIATRICS ◽  
2017 ◽  
Vol 139 (3) ◽  
pp. e20162975 ◽  
Author(s):  
Monica S. Cooper ◽  
Mark T. Mackay ◽  
Michael Fahey ◽  
Dinah Reddihough ◽  
Susan M. Reid ◽  
...  

2013 ◽  
Vol 34 (9) ◽  
pp. 2500-2506 ◽  
Author(s):  
Adrienne R. Harvey ◽  
Melinda Randall ◽  
Susan M. Reid ◽  
Katherine J. Lee ◽  
Christine Imms ◽  
...  

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Elsa Tillberg ◽  
Bengt Isberg ◽  
Jonas K. E. Persson

Abstract Background The purpose of this study was to describe clinical presentation, epilepsy, EEG, extent and site of the underlying cerebral lesion with special reference towards aetiologic background factors in a population-based group of children with hemiplegic cerebral palsy. Methods Forty-seven children of school- age, fulfilling the SPCE (Surveillance of Cerebral palsy in Europe)-criteria of hemiplegic cerebral palsy, identified via the Swedish cerebral palsy register, were invited and asked to participate in the study. Results Fifteen boys and six girls participated. Of the sixteen children born at term, five had no risk factors for cerebral palsy. Two out of five preterm children presented additional risk factors. Debut of motor impairment was observed in the first year of life in sixteen children. Age at diagnosis varied from 2 months to 6 years. Epilepsy was common and associated with grey- and white matter injury. Conclusions Recognizing the importance of risk factors for cerebral palsy, any child with these risk factors should be offered a check-up by a paediatrician or a paediatric neurologist. Thereby reducing diagnostic delay. Epilepsy is common in hemiplegic cerebral palsy and associated with grey- and white matter injury in this cohort.


2006 ◽  
Vol 27 (2) ◽  
pp. 270-281 ◽  
Author(s):  
Alexander Drobyshevsky ◽  
Matthew Derrick ◽  
Alice Mary Wyrwicz ◽  
Xinhai Ji ◽  
Ila Englof ◽  
...  

PLoS ONE ◽  
2014 ◽  
Vol 9 (6) ◽  
pp. e100451 ◽  
Author(s):  
Xuetao Mu ◽  
Binbin Nie ◽  
Hong Wang ◽  
Shaofeng Duan ◽  
Zan Zhang ◽  
...  

2010 ◽  
Vol 3 (11-12) ◽  
pp. 678-688 ◽  
Author(s):  
J. C. Silbereis ◽  
E. J. Huang ◽  
S. A. Back ◽  
D. H. Rowitch

2021 ◽  
pp. 088307382199361
Author(s):  
Jayanti Prabha ◽  
Areesha Alam ◽  
Chandrakanta Kumar ◽  
Rashmi Kumar ◽  
Neera Kohli

Background: Few studies have focused on magnetic resonance imaging (MRI) brain findings associated with functional mobility in cerebral palsy. Objective: To determine association between MRI findings and Gross Motor Functional Classification System (GMFCS) levels in cerebral palsy. Methods: Prospective-observational study conducted in Pediatric Neurology Clinic at a public teaching hospital, Northern India. First 3 new cases of cerebral palsy were enrolled on particular neuro-clinic day per week for 1 year. Functional mobility was classified according to GMFCS. Association between MRI findings, cerebral palsy type, and GMFCS levels were evaluated using χ2 test. Results: A total of 138 cases (mean age 2.71 [SD = 1.91] years; male [64.5%]) were enrolled. Reported types of cerebral palsy were as follows: spastic quadriplegia (47.8%), spastic diplegia (28.35%), spastic hemiplegia (11.6%), extrapyramidal (6.5%), and ataxic/hypotonic (5.8%). GMFCS were classified into level 1 (13%), level 2 (7.2%), level 3 (4.3%), level 4 (10.9%), and level 5 (64.5%). Spastic quadriplegia and extrapyramidal cerebral palsy were significantly associated with higher (severe) levels (IV and V), whereas spastic diplegia and hemiplegia were significantly associated with lower (mild) levels (I-III) of GMFCS. MRI features of periventricular white matter injury, deep gray matter injury, basal ganglia and thalamic changes, and superficial gray matter injury were significantly associated with severe levels of GMFCS (V and IV). MRI was normal in 8 children (5 = mild category, 3 = severe category). Conclusion: Severe cerebral palsy is most often associated with spastic quadriplegia, extrapyramidal cerebral palsy, superficial gray matter lesions, deep gray matter lesions, and periventricular white matter injury. This information is useful for anticipating and addressing the needs of children with cerebral palsy and for prognostication.


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