scholarly journals What can magnetic resonance imaging tell us about white matter injury in term-born children with cerebral palsy?

2015 ◽  
Vol 57 ◽  
pp. 51-51
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cerebral Palsy ◽  
White Matter ◽  
Magnetic Resonance ◽  
White Matter Injury ◽  
Resonance Imaging ◽  
Children With Cerebral Palsy

scholarly journals Brain Magnetic Resonance Imaging Pattern in Cerebral Palsy

2021 ◽  
Author(s):  
Prastiya Indra Gunawan ◽  
Riza Noviandi ◽  
Sunny Mariana Samosir
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cerebral Palsy ◽  
White Matter ◽  
Magnetic Resonance ◽  
Disease Severity ◽  
Grey Matter ◽  
White Matter Injury ◽  
Control Group ◽  
Resonance Imaging ◽  
Grey Matter Injury

Abstract Background Cerebral palsy (CP) leads to a common static motor neurological disease in children that can be demonstrated with varied neuroimaging findings. Magnetic Resonance Imaging (MRI) has a vital role of determining the presence of brain injury and its extent, with any possibility of determining pathogenic pattern and disease severity. The objective of the study is to evaluate the neuroimaging findings in CP and their correlation to disease severity. Method The research was case-control study, consecutive and complete records of all patients who had a clinical diagnosis of CP and performed a head MRI between 2018 and 2019 were enrolled in this study. Cases group were children diagnosed as severe CP with The Gross Motor Function Classification System (GMFCS) IV-V. Control group were children confirmed as CP with GMFCS I-III. Brain imaging was examined by MRI, in which the abnormalities were classified into grey matter or white matter injury, focal vascular disorder and brain malformation. Kruskal-Wallis statistical analysis was applied to identify the correlation. Results Almost 60 cases were reviewed. White matter injury, malformation and focal vascular insult were not correlated significantly to CP severity (OR = 0.73; 95% CI = 0.2-2.2; p = 0.78 and OR = 0.61; 95% CI = 0.2-1.9; p = 0.57 and OR = 2.034; 95% CI = 0.51-0.76; p = 0.63, respectively). Grey matter injury was more frequent discovered in severe CP (50%) and increased the risk of CP severity (OR = 9; 95% CI = 2.2 – 36; p = 0.002). Conclusion Grey matter injury is considered the most frequent abnormalities of Brain MRI in CP and it could increase the risk of severity.

Adverse effects of erenumab on cerebral proliferative angiopathy: A case report

Cephalalgia ◽  
2020 ◽  
pp. 033310242095048
Author(s):  
Laura L Lehman ◽  
Rebecca Bruccoleri ◽  
Amy Danehy ◽  
Julie Swanson ◽  
Christine Mrakotsky ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
Blood Brain Barrier ◽  
Vascular Malformations ◽  
Hippocampal Sclerosis ◽  
White Matter Injury ◽  
Brain Barrier ◽  
Resonance Imaging ◽  
Blood Brain

Background Cerebral proliferative angiopathy is a vascular malformation associated with compromised blood-brain barrier and with migraine-like headache. Treating blood-brain barrier-compromised patients with erenumab, an anti-calcitonin gene-related peptide receptor monoclonal antibody, may be risky. Case We describe a case of a 22-year-old chronic migraine patient with cerebral proliferative angiopathy who presented to our hospital in status epilepticus 2 d after his first dose of erenumab. Serial magnetic resonance imaging (MRI) studies demonstrated progressive areas of diffusion restriction including the brain tissue adjacent to the cerebral proliferative angiopathy, bilateral white matter and hippocampi. His 6-month post-presentation magnetic resonance imaging was notable for white matter injury, encephalomalacia surrounding cerebral proliferative angiopathy and bilateral hippocampal sclerosis. He remains clinically affected with residual symptoms, including refractory epilepsy and cognitive deficits. Conclusion The evidence presented in this case supports further investigation into potential deleterious side effects of erenumab in patients with compromised blood-brain barrier, such as individuals with intracranial vascular malformations.

scholarly journals Evaluation of the femoral midshaft in children with cerebral palsy using magnetic resonance imaging

2008 ◽  
Vol 20 (4) ◽  
pp. 609-615 ◽  
Author(s):  
C. M. Modlesky ◽  
S. A. Kanoff ◽  
D. L. Johnson ◽  
P. Subramanian ◽  
F. Miller
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cerebral Palsy ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Children With Cerebral Palsy

Magnetic resonance imaging, risk factors and co-morbidities in children with cerebral palsy

2010 ◽  
Vol 258 (3) ◽  
pp. 471-478 ◽  
Author(s):  
Rajniti Prasad ◽  
Nishant Verma ◽  
A. Srivastava ◽  
B. K. Das ◽  
O. P. Mishra
Keyword(s):  
Magnetic Resonance Imaging ◽  
Risk Factors ◽  
Cerebral Palsy ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Children With Cerebral Palsy
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