scholarly journals A coordinated national UK liver transplant program response, prioritising waitlist recipients with the highest need, provided excellent outcomes during the first wave of the COVID‐19 pandemic

2021 ◽  
Author(s):  
Steven Masson ◽  
Rhiannon Taylor ◽  
Julie Whitney ◽  
Anya Adair ◽  
Magdy Attia ◽  
...  
2014 ◽  
Vol 25 (3) ◽  
pp. 159-162 ◽  
Author(s):  
Clara Tan-Tam ◽  
Pamela Liao ◽  
Julio S Montaner ◽  
Mark W Hull ◽  
Charles H Scudamore ◽  
...  

BACKGROUND: The demand for definitive management of end-stage organ disease in HIV-infected Canadians is growing. Until recently, despite international evidence of good clinical outcomes, HIV-infected Canadians with end-stage liver disease were ineligible for transplantation, except in British Columbia (BC), where the liver transplant program of BC Transplant has accepted these patients for referral, assessment, listing and provision of liver allograft. There is a need to evaluate the experience in BC to determine the issues surrounding liver transplantation in HIV-infected patients.METHODS: The present study was a chart review of 28 HIV-infected patients who were referred to BC Transplant for liver transplantation between 2004 and 2013. Data regarding HIV and liver disease status, initial transplant assessment and clinical outcomes were collected.RESULTS: Most patients were BC residents and were assessed by the multidisciplinary team at the BC clinic. The majority had undetectable HIV viral loads, were receiving antiretroviral treatments and were infected with hepatitis C virus (n=16). The most common comorbidities were anxiety and mood disorders (n=4), and hemophilia (n=4). Of the patients eligible for transplantation, four were transplanted for autoimmune hepatitis (5.67 years post-transplant), nonalcoholic steatohepatitis (2.33 years), hepatitis C virus (2.25 years) and hepatitis B-delta virus coinfection (recent transplant). One patient died from acute renal failure while waiting for transplantation. Ten patients died during preassessment and 10 were unsuitable transplant candidates. The most common reason for unsuitability was stable disease not requiring transplantation (n=4).CONCLUSIONS: To date, interdisciplinary care and careful selection of patients have resulted in successful outcomes including the longest living HIV-infected post-liver transplant recipient in Canada.


2005 ◽  
Vol 37 (2) ◽  
pp. 1201-1202 ◽  
Author(s):  
G. Varela-Fascinetto ◽  
R. Dávila-Pérez ◽  
J. Nieto-Zermeño ◽  
E. Bracho-Blanchet ◽  
V. Fuentes-Garcı́a ◽  
...  

1988 ◽  
Vol 17 (1) ◽  
pp. 195-206
Author(s):  
Alma E. Heyl ◽  
Sandra Staschak ◽  
Pat Folk ◽  
Vicki Fioravanti

2019 ◽  
Vol 18 (1) ◽  
pp. 187-192 ◽  
Author(s):  
Victoria Mainardi ◽  
Karina Rando ◽  
Marcelo Valverde ◽  
Daniela Olivari ◽  
Jorge Castelli ◽  
...  

1989 ◽  
Vol 9 (03) ◽  
pp. 159-167 ◽  
Author(s):  
Byers Shaw

1997 ◽  
Vol 43 (8) ◽  
pp. 1546-1554 ◽  
Author(s):  
Peter E Hickman ◽  
Julia M Potter ◽  
Amadeo J Pesce

Abstract Liver transplantation is an accepted therapy for end-stage liver disease. After allografting, a variety of clinical problems may require laboratory involvement for accurate and timely diagnosis and intervention. Critical factors in the choice of a laboratory test menu to support a transplant program include turnaround times that support clinical decisionmaking, real diagnostic value, and real value for money. Particular clinical problems, whose early presentation must be anticipated, include graft ischemia, primary nonfunction, and hepatic artery thrombosis. Acute rejection is common at 5–10 days posttransplantation, the principal target being the biliary tree. Longer-term problems are associated with the therapeutic drug measurement of cyclosporin A and, increasingly, tacrolimus (FK506); the side effects of immunosuppressant therapy also require monitoring. A successful liver transplant program can be adequately supported with a simple battery of automated tests that are cheap, fast, and available at all times.


Author(s):  
R.R. Ossami Saidy ◽  
Muenevver Demir ◽  
Pauline Nibbe ◽  
Eva‐Maria Dobrindt ◽  
Robert Oellinger ◽  
...  

2005 ◽  
Vol 9 (4) ◽  
pp. 552-552
Author(s):  
E DIXON ◽  
S SCHNEEWEISS ◽  
J PASIEKA ◽  
O BATHE ◽  
F SUTHERLAND ◽  
...  

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