scholarly journals Self‐limited HBV infection of the recipient does not reactivate after liver transplantation: Observations from a 30‐year liver transplant program

2020 ◽  
Author(s):  
R.R. Ossami Saidy ◽  
Muenevver Demir ◽  
Pauline Nibbe ◽  
Eva‐Maria Dobrindt ◽  
Robert Oellinger ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Transplant ◽  
Hbv Infection ◽  
Transplant Program

scholarly journals HIV and Liver transplantation: The British Columbia Experience, 2004 to 2013

2014 ◽  
Vol 25 (3) ◽  
pp. 159-162 ◽  
Author(s):  
Clara Tan-Tam ◽  
Pamela Liao ◽  
Julio S Montaner ◽  
Mark W Hull ◽  
Charles H Scudamore ◽  
...  
Keyword(s):  
British Columbia ◽  
Liver Transplantation ◽  
Hepatitis C Virus ◽  
Liver Disease ◽  
Hepatitis C ◽  
Liver Transplant ◽  
Clinical Outcomes ◽  
Disease Status ◽  
Transplant Program ◽  
End Stage

BACKGROUND: The demand for definitive management of end-stage organ disease in HIV-infected Canadians is growing. Until recently, despite international evidence of good clinical outcomes, HIV-infected Canadians with end-stage liver disease were ineligible for transplantation, except in British Columbia (BC), where the liver transplant program of BC Transplant has accepted these patients for referral, assessment, listing and provision of liver allograft. There is a need to evaluate the experience in BC to determine the issues surrounding liver transplantation in HIV-infected patients.METHODS: The present study was a chart review of 28 HIV-infected patients who were referred to BC Transplant for liver transplantation between 2004 and 2013. Data regarding HIV and liver disease status, initial transplant assessment and clinical outcomes were collected.RESULTS: Most patients were BC residents and were assessed by the multidisciplinary team at the BC clinic. The majority had undetectable HIV viral loads, were receiving antiretroviral treatments and were infected with hepatitis C virus (n=16). The most common comorbidities were anxiety and mood disorders (n=4), and hemophilia (n=4). Of the patients eligible for transplantation, four were transplanted for autoimmune hepatitis (5.67 years post-transplant), nonalcoholic steatohepatitis (2.33 years), hepatitis C virus (2.25 years) and hepatitis B-delta virus coinfection (recent transplant). One patient died from acute renal failure while waiting for transplantation. Ten patients died during preassessment and 10 were unsuitable transplant candidates. The most common reason for unsuitability was stable disease not requiring transplantation (n=4).CONCLUSIONS: To date, interdisciplinary care and careful selection of patients have resulted in successful outcomes including the longest living HIV-infected post-liver transplant recipient in Canada.

Surgical aspects of pediatric liver transplantation. Living donor liver transplant program in Hungary

2008 ◽  
Vol 149 (27) ◽  
pp. 1271-1275 ◽  
Author(s):  
László Kóbori ◽  
Zoltán Máthé ◽  
János Fazakas ◽  
Zsuzsanna Gerlei ◽  
Attila Doros ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Transplant ◽  
Living Donor ◽  
Pediatric Liver Transplantation ◽  
Donor Liver ◽  
Transplant Program ◽  
Kaplan Meier ◽  
Living Donor Liver Transplant ◽  
Donor Liver Transplant ◽  
Surgical Aspects

A májátültetés jelenti a gyermekkori végstádiumú májbetegségek egyetlen kezelési módját. A split, majd az ezt követően kifejlesztett élő donoros májátültetés ma már rutinbeavatkozásnak számít, és a gyermekkori átültetések alapját jelentik. Az átlagos Kaplan–Meier-féle meghatározás szerinti 1, illetve 5 éves túlélés 80–90% feletti. A donormáj splittelése során két májbetegen segíthetünk. A bal oldali laterális szegmenteket általában gyermekeknek, a nagyobb jobb oldalt felnőtteknek ültetjük át. Természetesen többféle kombináció jön szóba attól függően, hogy élő donoros vagy split-, vagy redukált májátültetésről van szó. Az átültetéshez szükséges májszövet mennyisége a testsúly minimum 1%-át jelenti. A hazai több mint 340 májátültetés során 27 gyermek (14 parciális graft) májátültetéséről számolhatunk be, és elindult az élődonor-program is. Az alkalmazott technikák eredményeit és szövődményeit is figyelembe véve elmondható, hogy megfelelően szigorú kivizsgálási protokollok betartásával, a sebészi, aneszteziológiai és intenzív osztályos kezelés megfelelő szintű fejlesztésével a hazai átültetések eredményei nemzetközi szintre emelkedtek. Az utolsó 5 év átlagos túlélése 80% feletti volt.

Recurrence of graft steatosis after liver transplantation for cryptogenic cirrhosis in recently commenced liver transplant program

2016 ◽  
Vol 35 (3) ◽  
pp. 222-224 ◽  
Author(s):  
Rohan C. Siriwardana ◽  
Madunil Anuk Niriella ◽  
Anuradha Supun Dassanayake ◽  
Chandika Anuradha Habarakada Liyanage ◽  
Bhagya Gunetilleke ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Transplant ◽  
Cryptogenic Cirrhosis ◽  
Transplant Program

scholarly journals Organización y desarrollo de un programa de trasplante hepático en Mar del Plata. Resultados iniciales (2010-2018)

2019 ◽  
Vol 111 (4) ◽  
pp. 207-226
Author(s):  
Diego L. Fernández ◽  
◽  
Federico W. García ◽  
Ricardo A. Bracco
Keyword(s):  
Liver Transplantation ◽  
Liver Transplant ◽  
Geographic Area ◽  
Regulatory Agencies ◽  
Hepatitis C Virus Infection ◽  
Actuarial Survival ◽  
The Past ◽  
Transplant Program ◽  
Initial Results ◽  
Late Postoperative Period

Background: Over the past 30 years, new liver transplant programs have emerged as a response to the increasing use of this therapy to treat irreversible liver failure. Objective: the aim of this presentation is to describe the organization, development and initial results of a Liver Transplant Program in Mar del Plata. Material and methods: A team of professionals trained in liver transplantation was created, with specialists in surgery, anesthesiology, intensive care, hepatology, hemotherapy, hematology, and registered nurses and nurse scrubs granted by regulatory agencies. Building alterations, and technical and adaptations were implemented. Thirty-two transplantations were performed with complete cadaveric donor in patients from neighboring localities (55%) and from Mar del Plata (45%). The most common etiologies of cirrhosis were chronic hepatitis C virus infection and alcohol abuse. Results: Operative mortality was 12.5%. Actuarial survival at 55 months of the 32 recipients was 75%. Six bile drug strictures late postoperative period which were treated successfully trated with a conservative approach Conclusions: the Liver Transplant Program in Mar del Plata provides care to the geographic area of the southeast of the province of Buenos Aires. The initial results are consistent with those expected for the current standards in liver transplantation.

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