Retinal prostheses: Where to from here?

Author(s):  
Penelope J. Allen
Keyword(s):  
2018 ◽  
pp. 315 ◽  
Author(s):  
Yukari Nakano ◽  
Yasuo Terasawa ◽  
Hiroyuki Kanda ◽  
Jun Ohta ◽  
Hajime Sawai ◽  
...  

Retinal prostheses are devices that receive an environmental visual stimulus, process it, and stimulate the degenerated retinal areas in order to produce a functionally efficient visual perception. Indications for implantation of these devices include hereditary retinal degenerations like retinitis pigmentosa, choroideremia, rod-cone dystrophy, and acquired macular diseases like geographic atrophy or fibrosis due to age-related macular degeneration. Clinically applied retinal prosthesis approaches can be classified as; epiretinal, subretinal, suprachoroidal, and scleral (transscleral suprachoroidal). In this paper, approaches of retinal prosthesis research groups, results of clinical trials, and the latest advances in their projects will be provided.


Recent developments in understanding the pathophysiology of retinitis pigmentosa (RP) have shown that there have been new hopes in the treatment of this disease which can cause severe vision loss. Proven therapy for RP-associated photoreceptor loss and retinal pigment epithelial damage has not yet been reported. New or experimental approaches for the treatment of RP include platelet-rich plasma, gene therapy, transplantation of fetal retinal cells or stem cells, and electronic retinal prostheses.


2019 ◽  
Vol 55 (2) ◽  
pp. 159-166
Author(s):  
Goran Pelčić ◽  
Martina Brumini ◽  
Ivana Crnković ◽  
Zvjezdana Alpeza-Dunato ◽  
Tea Čaljkušić-Mance ◽  
...  

Argus® II prva je retinalna proteza odobrena za liječenje slijepih pacijenata koji boluju od retinalne pigmentoze. Godine 2011. primila je oznaku CE-a (engl. European Committee) te 2013. odobrenje FDA-a (engl. Food and Drug Administration). Retinalna proteza pruža stabilnu, sigurnu i dugotrajnu retinalnu stimulaciju. Poboljšanje vida s retinalnim protezama ovisi o poboljšanju vidne rezolucije, razvoju točnog neuralnog obrasca za obradu slike i poboljšanju biološke kompatibilnosti uređaja kako bi se osigurala dugotrajnost. Jednom tema narodne predaje i znanstvene fantastike, ideja povratka vida slijepim osobama danas se približava realnosti.


2009 ◽  
Vol 6 (6) ◽  
pp. 065004 ◽  
Author(s):  
David C Ng ◽  
Shun Bai ◽  
Jiawei Yang ◽  
Nhan Tran ◽  
Efstratios Skafidas

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