Simultaneous vs. sequential and unipolar vs. multipolar stimulation in retinal prostheses

Retinal prostheses are devices that receive an environmental visual stimulus, process it, and stimulate the degenerated retinal areas in order to produce a functionally efficient visual perception. Indications for implantation of these devices include hereditary retinal degenerations like retinitis pigmentosa, choroideremia, rod-cone dystrophy, and acquired macular diseases like geographic atrophy or fibrosis due to age-related macular degeneration. Clinically applied retinal prosthesis approaches can be classified as; epiretinal, subretinal, suprachoroidal, and scleral (transscleral suprachoroidal). In this paper, approaches of retinal prosthesis research groups, results of clinical trials, and the latest advances in their projects will be provided.

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Treatments Being Developed in Retinitis Pigmentosa

Güncel Retina Dergisi (Current Retina Journal) ◽

10.37783/crj-0253 ◽

2021 ◽

pp. 150-154

Keyword(s):

Retinitis Pigmentosa ◽

Retinal Pigment Epithelial ◽

Vision Loss ◽

Platelet Rich Plasma ◽

Retinal Pigment ◽

Retinal Prostheses ◽

Pigment Epithelial ◽

Recent Developments ◽

Severe Vision Loss ◽

Experimental Approaches

Recent developments in understanding the pathophysiology of retinitis pigmentosa (RP) have shown that there have been new hopes in the treatment of this disease which can cause severe vision loss. Proven therapy for RP-associated photoreceptor loss and retinal pigment epithelial damage has not yet been reported. New or experimental approaches for the treatment of RP include platelet-rich plasma, gene therapy, transplantation of fetal retinal cells or stem cells, and electronic retinal prostheses.

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Fabrication and evaluation of nanostructured microelectrodes for high-spatial resolution in retinal prostheses

Microsystem Technologies ◽

10.1007/s00542-018-4276-5 ◽

2019 ◽

Vol 25 (5) ◽

pp. 2099-2107

Author(s):

Yeok In Choi ◽

Kangil Kim ◽

Sangmin Lee

Keyword(s):

Spatial Resolution ◽

High Spatial Resolution ◽

Retinal Prostheses

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A review on the current status of retinal prostheses (bionic eye)

Medicina Fluminensis ◽

10.21860/medflum2019_218809 ◽

2019 ◽

Vol 55 (2) ◽

pp. 159-166

Author(s):

Goran Pelčić ◽

Martina Brumini ◽

Ivana Crnković ◽

Zvjezdana Alpeza-Dunato ◽

Tea Čaljkušić-Mance ◽

...

Keyword(s):

Drug Administration ◽

Food And Drug Administration ◽

Current Status ◽

Retinal Prostheses ◽

European Committee ◽

Bionic Eye

Argus® II prva je retinalna proteza odobrena za liječenje slijepih pacijenata koji boluju od retinalne pigmentoze. Godine 2011. primila je oznaku CE-a (engl. European Committee) te 2013. odobrenje FDA-a (engl. Food and Drug Administration). Retinalna proteza pruža stabilnu, sigurnu i dugotrajnu retinalnu stimulaciju. Poboljšanje vida s retinalnim protezama ovisi o poboljšanju vidne rezolucije, razvoju točnog neuralnog obrasca za obradu slike i poboljšanju biološke kompatibilnosti uređaja kako bi se osigurala dugotrajnost. Jednom tema narodne predaje i znanstvene fantastike, ideja povratka vida slijepim osobama danas se približava realnosti.

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