scholarly journals FGF13 Enhances Resistance to Platinum Drugs by Regulating hCTR1 and ATP7A via a Microtubule‐Stabilizing Effect

2021 ◽  
Author(s):  
Hang Yu ◽  
Handong Wang ◽  
Anran Qie ◽  
Jiaqi Wang ◽  
Yueping Liu ◽  
...  
Keyword(s):  
Platinum Drugs ◽  
Stabilizing Effect

Economical Pavement Design by Stabilizing Effect of Fly Ash and Lime

2012 ◽  
Vol 2 (3) ◽  
pp. 121-124
Author(s):  
Prof. N. R. Patil Prof. N. R. Patil ◽  
◽  
Prof. D. R. Kulkarni Prof. D. R. Kulkarni ◽  
Prof. S. D. Talegaonkar Prof. S. D. Talegaonkar
Keyword(s):  
Fly Ash ◽  
Pavement Design ◽  
Stabilizing Effect

The Stabilizing Effect of Pre-Equilibria: A Trifluoromethyl Complex as CF2 Reservoir in Catalytic Olefin Difluorocarbenation

2020 ◽  
Author(s):  
Thomas Louis-Goff ◽  
Huu Vinh Trinh ◽  
Eileen Chen ◽  
Arnold L. Rheingold ◽  
Christian Ehm ◽  
...  
Keyword(s):  
High Selectivity ◽  
Side Reactions ◽  
Theoretical Studies ◽  
Attractive Feature ◽  
Catalyst Recovery ◽  
Wide Range ◽  
Stabilizing Effect ◽  
Experimental And Theoretical Studies

A new, efficient, catalytic difluorocarbenation of olefins to give 1,1-difluorocyclopropanes is presented. The catalyst, an organobismuth complex, uses TMSCF<sub>3</sub> as a stoichiometric difluorocarbene source. We demonstrate both the viability and robustness of this reaction over a wide range of alkenes and alkynes, including electron-poor alkenes, to generate the corresponding 1,1-difluorocyclopropanes and 1,1-difluorocyclopropenes. Ease of catalyst recovery from the reaction mixture is another attractive feature of this method. In depth experimental and theoretical studies showed that the key difluorocarbene-generating step proceeds through a bismuth non-redox synchronous mechanism generating a highly reactive free CF<sub>2</sub> in an endergonic pre-equilibrium. It is the reversibility when generating the difluorocarbene that accounts for the high selectivity, while minimizing CF<sub>2</sub>-recombination side-reactions.

ALLVAC 6Al-6V-2Sn

Alloy Digest ◽  
1991 ◽  
Vol 40 (8) ◽  
Keyword(s):  
Corrosion Resistance ◽  
Titanium Alloy ◽  
Physical Properties ◽  
Tensile Properties ◽  
Heat Treating ◽  
Beta Titanium Alloy ◽  
Beta Titanium ◽  
Stabilizing Effect ◽  
Alpha Beta

Abstract ALLVAC 6A1-6V-2Sn is a highly beta stabilized alpha + beta titanium alloy, a modification of the 6 A1-4V system. Added vanadium plus copper and iron produce the stabilizing effect. This datasheet provides information on composition, physical properties, elasticity, and tensile properties as well as creep. It also includes information on corrosion resistance as well as forming, heat treating, machining, and joining. Filing Code: Ti-98. Producer or source: Teledyne Allvac.

Haemoglobin stabilization during lyophilization with saccharides. Perturbation effect of polyethylene glycols

1981 ◽  
Vol 46 (8) ◽  
pp. 1856-1859 ◽  
Author(s):  
Tomáš I. Přistoupil ◽  
Stanislav Ulrych ◽  
Marie Kramlová
Keyword(s):  
Polyethylene Glycols ◽  
Stabilizing Effect ◽  
Perturbation Effect ◽  
Effect Of Glucose ◽  
Mechanical Nature

The stabilizing effect of glucose and sucrose upon haemoglobin molecules against oxidation during lyophilization was perturbated by the presence of fluid or greasy polyethylene glycols (m.w. 300-600 daltons) but not of the rigid ones (m.w. 1 500-6 000 daltons). The results corroborate the idea of a simple mechanical nature of haemoglobin stabilization under study.

Nanoparticle-based drug delivery systems with platinum drugs for overcoming cancer drug resistance

2021 ◽  
Author(s):  
Peng Xie ◽  
Yushu Wang ◽  
Dengshuai Wei ◽  
Lingpu Zhang ◽  
Bin Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Resistance ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Cancer Drug ◽  
Platinum Drugs ◽  
Effective Strategy ◽  
Platinum Drug ◽  
Cancer Drug Resistance ◽  
Platinum Drug Resistance

The mechanisms of chemoresistance and nanoparticle-based drug delivery systems for platinum drugs were detailed summarized in this review. The current combination therapy provided an effective strategy to overcome the platinum drug resistance.

scholarly journals Synthesis and Spectroscopic Investigation of a Hexaaza Lanthanum(III) Macrocycle with a Hybrid-Type G4 DNA Stabilizing Effect

2021 ◽  
Vol 60 (4) ◽  
pp. 2122-2126
Author(s):  
Marta A. Fik-Jaskółka ◽  
Izabela Pospieszna-Markiewicz ◽  
Giovanni N. Roviello ◽  
Maciej Kubicki ◽  
Wanda Radecka-Paryzek ◽  
...  
Keyword(s):  
Spectroscopic Investigation ◽  
Hybrid Type ◽  
G4 Dna ◽  
Stabilizing Effect

scholarly journals Tin Complexes of 4-(Benzylideneamino)benzenesulfonamide: Synthesis, Structure Elucidation and Their Efficiency as PVC Photostabilizers

Polymers ◽  
2021 ◽  
Vol 13 (15) ◽  
pp. 2434
Author(s):  
Hassan Ghani ◽  
Emad Yousif ◽  
Dina S. Ahmed ◽  
Benson M. Kariuki ◽  
Gamal A. El-Hiti
Keyword(s):  
Vinyl Chloride ◽  
Structure Elucidation ◽  
Poly Vinyl Chloride ◽  
Polymeric Chains ◽  
Process Decomposition ◽  
Stabilizing Effect ◽  
Surface Alteration ◽  
Tin Complexes ◽  
High Yields ◽  
Harsh Conditions

Poly(vinyl chloride) (PVC) suffers from photo-xidation and photodegradation when exposed to harsh conditions. Application of PVC thus relies on the development of ever more efficient photostabilizers. The current research reports the synthesis of new complexes of tin and their assessment as poly(vinyl chloride) photostabilizers. The three new complexes were obtained in high yields from reaction of 4-(benzylideneamino)benzenesulfonamide and tin chlorides. Their structures were elucidated using different tools. The complexes were mixed with poly(vinyl chloride) at a very low concentration and thin films were made from the blends. The effectiveness of the tin complexes as photostabilizers has been established using a variety of methods. The new tin complexes led to a decrease in weight loss, formation of small residues, molecular weight depression, and surface alteration of poly(vinyl chloride) after irradiation. The additives act by absorption of ultraviolet light, removal the active chlorine produced through a dehydrochlorination process, decomposition of peroxides, and coordination with the polymeric chains. The triphenyltin complex showed the greatest stabilizing effect against PVC photodegradation as a result of its high aromaticity.

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