2‐Methoxystypandrone inhibits signal transducer and activator of transcription 3 and nuclear factor‐κB signaling by inhibiting Janus kinase 2 and IκB kinase

Shan Kuang; Chunting Qi; Jiawei Liu; Xiaoxiao Sun; Qing Zhang; Zhenhua Sima; Jingli Liu; Wuguo Li; Qiang Yu

doi:10.1111/cas.12359

2‐Methoxystypandrone inhibits signal transducer and activator of transcription 3 and nuclear factor‐κB signaling by inhibiting Janus kinase 2 and IκB kinase

Cancer Science ◽

10.1111/cas.12359 ◽

2014 ◽

Vol 105 (4) ◽

pp. 473-480 ◽

Cited By ~ 15

Author(s):

Shan Kuang ◽

Chunting Qi ◽

Jiawei Liu ◽

Xiaoxiao Sun ◽

Qing Zhang ◽

...

Keyword(s):

Nuclear Factor Κb ◽

Janus Kinase ◽

Nuclear Factor ◽

Signal Transducer ◽

Janus Kinase 2 ◽

Iκb Kinase ◽

Transcription 3

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Faculty Opinions recommendation of Janus kinase 2/signal transducer and activator of transcription 3 inhibitors attenuate the effect of cardiotrophin-like cytokine factor 1 and human focal segmental glomerulosclerosis serum on glomerular filtration barrier.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725428053.793530397 ◽

2017 ◽

Author(s):

Jochen Reiser

Keyword(s):

Glomerular Filtration ◽

Focal Segmental Glomerulosclerosis ◽

Janus Kinase ◽

Signal Transducer ◽

Janus Kinase 2 ◽

Glomerular Filtration Barrier ◽

Filtration Barrier ◽

Segmental Glomerulosclerosis ◽

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Qingnaoyizhi decoction suppresses the formation of glial fibrillary acidic protein-positive cells in cultured neural stem cells by inhibiting the Janus kinase 2 / signal transducer and activator of transcription 3 signaling pathway

Journal of Traditional Chinese Medicine ◽

10.1016/s0254-6272(15)30011-x ◽

2015 ◽

Vol 35 (1) ◽

pp. 69-76 ◽

Cited By ~ 1

Author(s):

Wu Yanqing ◽

Jing Zhiwei ◽

Qin Xiude ◽

Zhou Zhen ◽

Wang Kai ◽

...

Keyword(s):

Stem Cells ◽

Glial Fibrillary Acidic Protein ◽

Neural Stem Cells ◽

Signaling Pathway ◽

Janus Kinase ◽

Acidic Protein ◽

Signal Transducer ◽

Janus Kinase 2 ◽

Transcription 3

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Inhibition of Janus Kinase 2 -Signal Transducer and Activator of Transcription 3 (JAK2-STAT3) Pathway as a Therapeutic Option for Pulmonary Hypertension

10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5283 ◽

2019 ◽

Author(s):

N.D.R. Yerabolu ◽

A. Weiss ◽

N. Weissmann ◽

H.A. Ghofrani ◽

F. Grimminger ◽

...

Keyword(s):

Pulmonary Hypertension ◽

Therapeutic Option ◽

Janus Kinase ◽

Signal Transducer ◽

Janus Kinase 2 ◽

Stat3 Pathway ◽

Transcription 3

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Anticancer Activity of Tubulosine through Suppression of Interleukin-6-Induced Janus Kinase 2/Signal Transducer and Activation of Transcription 3 Signaling

Journal of Breast Cancer ◽

10.4048/jbc.2019.22.e34 ◽

2019 ◽

Vol 22 (3) ◽

pp. 362 ◽

Cited By ~ 3

Author(s):

Byung-Hak Kim ◽

Eun Hee Yi ◽

Yu-Chen Li ◽

In-Chul Park ◽

Jung Youl Park ◽

...

Keyword(s):

Anticancer Activity ◽

Interleukin 6 ◽

Janus Kinase ◽

Signal Transducer ◽

Janus Kinase 2 ◽

Activation Of Transcription ◽

Transcription 3

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Methanol extracts of Xanthium sibiricum roots inhibit inflammatory responses via the inhibition of nuclear factor-κB (NF-κB) and signal transducer and activator of transcription 3 (STAT3) in murine macrophages

Journal of Ethnopharmacology ◽

10.1016/j.jep.2015.07.038 ◽

2015 ◽

Vol 174 ◽

pp. 74-81 ◽

Cited By ~ 12

Author(s):

Anna Ju ◽

Young-Chang Cho ◽

Sayeon Cho

Keyword(s):

Inflammatory Responses ◽

Nuclear Factor Κb ◽

Nuclear Factor ◽

Signal Transducer ◽

Murine Macrophages ◽

Methanol Extracts ◽

Xanthium Sibiricum ◽

Transcription 3

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Non-coding RNA 886 promotes renal cell carcinoma growth and metastasis through the Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway

Molecular Medicine Reports ◽

10.3892/mmr.2017.7093 ◽

2017 ◽

Vol 16 (4) ◽

pp. 4273-4278 ◽

Cited By ~ 2

Author(s):

Jun Lei ◽

Ju-Hua Xiao ◽

Shou-Hua Zhang ◽

Zhi-Qiang Liu ◽

Kai Huang ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Signaling Pathway ◽

Renal Cell ◽

Janus Kinase ◽

Signal Transducer ◽

Janus Kinase 2 ◽

Non Coding Rna ◽

Transcription 3

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Signal transducer and activator of transcription 3 signaling upregulates fascin via nuclear factor-κB in gastric cancer: Implications in cell invasion and migration

Oncology Letters ◽

10.3892/ol.2014.1804 ◽

2014 ◽

Vol 7 (3) ◽

pp. 902-908 ◽

Cited By ~ 21

Author(s):

JUN YAO ◽

CUI-JUAN QIAN ◽

BEI YE ◽

ZHI-QIANG ZHAO ◽

JIE WEI ◽

...

Keyword(s):

Gastric Cancer ◽

Cell Invasion ◽

Nuclear Factor Κb ◽

Nuclear Factor ◽

Signal Transducer ◽

Invasion And Migration ◽

And Migration ◽

Transcription 3

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Inhibition of Janus Kinase 2/Signal Transducer and Activator of Transcription 3 Pathway Sensitization of LoVo Cells After 5-Chloro-2,4-Dihydroxypyridine Based 5-Fluorouracil Treatment

Nanoscience and Nanotechnology Letters ◽

10.1166/nnl.2018.2710 ◽

2018 ◽

Vol 10 (7) ◽

pp. 969-976

Author(s):

Lingna Zhou ◽

Mingyue Hu ◽

Yu Ma ◽

Yuan Li ◽

Sunkai Ling ◽

...

Keyword(s):

Janus Kinase ◽

Signal Transducer ◽

Janus Kinase 2 ◽

Lovo Cells ◽

Transcription 3

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Mangiferin amelioratesPorphyromonas gingivalis-induced experimental periodontitis by inhibiting phosphorylation of nuclear factor-κB and Janus kinase 1-signal transducer and activator of transcription signaling pathways

Journal of Periodontal Research ◽

10.1111/jre.12360 ◽

2016 ◽

Vol 52 (1) ◽

pp. 1-7 ◽

Cited By ~ 8

Author(s):

H. Li ◽

Q. Wang ◽

Y. Ding ◽

C. Bao ◽

W. Li

Keyword(s):

Signaling Pathways ◽

Nuclear Factor Κb ◽

Janus Kinase ◽

Nuclear Factor ◽

Signal Transducer ◽

Janus Kinase 1 ◽

Experimental Periodontitis

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Janus kinase 2 (V617F) mutation status, signal transducer and activator of transcription-3 phosphorylation and impaired neutrophil apoptosis in myelofibrosis with myeloid metaplasia

Leukemia ◽

10.1038/sj.leu.2404338 ◽

2006 ◽

Vol 20 (10) ◽

pp. 1800-1808 ◽

Cited By ~ 21

Author(s):

R A Mesa ◽

A Tefferi ◽

T S Lasho ◽

D Loegering ◽

R F McClure ◽

...

Keyword(s):

Janus Kinase ◽

Neutrophil Apoptosis ◽

Signal Transducer ◽

Janus Kinase 2 ◽

Myeloid Metaplasia ◽

Mutation Status ◽

Status Signal ◽

V617f Mutation ◽

Myelofibrosis With Myeloid Metaplasia ◽

Transcription 3

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