scholarly journals Pseudo-Chédiak-Higashi granules and Auer rods in mixed phenotype acute leukaemia, T/myeloid, not otherwise specified

2017 ◽  
Vol 180 (2) ◽  
pp. 175-175 ◽  
Author(s):  
Yu Aruga ◽  
Ayumu Arakawa ◽  
Kouji Ono ◽  
Chitose Ogawa ◽  
Hiromichi Matsushita
Keyword(s):  
Acute Leukaemia ◽  
Not Otherwise Specified ◽  
Mixed Phenotype

A dimorphic blast population demonstrates Philadelphia-positive mixed phenotype acute leukaemia

Pathology ◽  
2014 ◽  
Vol 46 (3) ◽  
pp. 244-246 ◽  
Author(s):  
Victoria Y. Ling ◽  
Meaghan Wall ◽  
Amanda Davis ◽  
Malgorzata Gorniak ◽  
George Grigoriadis
Keyword(s):  
Acute Leukaemia ◽  
Mixed Phenotype

scholarly journals Mixed phenotype acute leukaemia with giant inclusions

2010 ◽  
Vol 149 (1) ◽  
pp. 2-2
Author(s):  
Min Shi ◽  
Fang Cui ◽  
Bo Li ◽  
Shun-Yi Li ◽  
Hui-Jie Ma
Keyword(s):  
Acute Leukaemia ◽  
Mixed Phenotype

Auer rods in neutrophils in bone marrow and peripheral blood in mixed phenotype acute leukaemia in a child

2018 ◽  
Vol 184 (5) ◽  
pp. 708-708
Author(s):  
Samia Kabbage ◽  
Roberto Cupaiolo ◽  
Laurence Rozen ◽  
Anne Demulder
Keyword(s):  
Bone Marrow ◽  
Peripheral Blood ◽  
Acute Leukaemia ◽  
Mixed Phenotype

scholarly journals Venetoclax and Decitabine for T/Myeloid Mixed-Phenotype Acute Leukemia Not Otherwise Specified (MPAL NOS)

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Heather Klocke ◽  
Zhao Ming Dong ◽  
Craig O’Brien ◽  
Nicholas Burwick ◽  
Robert E. Richard ◽  
...  
Keyword(s):  
Stem Cell ◽  
Acute Leukemia ◽  
Stem Cell Transplant ◽  
Treatment Guidelines ◽  
Cell Transplant ◽  
Allogeneic Stem Cell Transplant ◽  
Not Otherwise Specified ◽  
Mixed Phenotype Acute Leukemia ◽  
One Year ◽  
Mixed Phenotype

T/myeloid mixed-phenotype acute leukemia not otherwise specified (MPAL NOS) is an uncommon and aggressive leukemia without well-established treatment guidelines, particularly when relapsed. Venetoclax plus a hypomethylating agent offers a promising option in this situation since studies support its use in both acute myeloid and, albeit with fewer data to date, acute T-cell-lymphoblastic leukemias. We report the successful eradication of T/myeloid MPAL NOS relapsed after allogeneic stem cell transplant with venetoclax plus decitabine. A consolidative allogeneic stem cell transplant from a second donor was subsequently performed, and the patient remained without evidence of disease more than one year later. Further investigation is indicated to evaluate venetoclax combined with hypomethylating agents and/or other therapies for the management of T/myeloid MPAL NOS.

scholarly journals Blinatumomab for paediatric mixed phenotype acute leukaemia

2021 ◽  
Author(s):  
Jack Bartram ◽  
Milena Balasch‐Carulla ◽  
Shashank Bhojaraja ◽  
Stuart Adams ◽  
Danny Cheng ◽  
...  
Keyword(s):  
Acute Leukaemia ◽  
Mixed Phenotype
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