Chemical exposure in fetal/early life: a possible explanation for the rapid increase in atopic dermatitis incidence

2015 ◽  
Vol 172 (3) ◽  
pp. 555-555
Author(s):  
C. Giwercman Carson
Keyword(s):  
Atopic Dermatitis ◽  
Early Life ◽  
Chemical Exposure

Host‐microbial interactions between PTGR2 and Bifidobacterium in the early life gut of atopic dermatitis children

2021 ◽  
Author(s):  
Jeong‐Hyun Kim ◽  
Seung‐Hwa Lee ◽  
Mi‐Jin Kang ◽  
Sun‐Goo Hwang ◽  
Yoon Mee Park ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Early Life ◽  
Microbial Interactions

scholarly journals Using Life History Calendars to Estimate in Utero and Early Life Pesticide Exposure of Latinx Children in Farmworker Families

2020 ◽  
Vol 17 (10) ◽  
pp. 3478 ◽  
Author(s):  
Sara A. Quandt ◽  
Dana C. Mora ◽  
Theresa L. Seering ◽  
Haiying Chen ◽  
Thomas A. Arcury ◽  
...  
Keyword(s):  
Cluster Analysis ◽  
Life History ◽  
Early Life ◽  
Pesticide Exposure ◽  
Chemical Exposure ◽  
In Utero ◽  
Early Life Exposure ◽  
Research Designs ◽  
Past Life ◽  
Secondary Analyses

(1) Background: Early life exposure to neurotoxic chemicals can have later impacts on child health. Most research designs must assume that current exposure is similar to past. Life history calendar methods can help to provide data on early life exposure. (2) Methods: Life history calendars were completed by mothers of 8-year-old children from Latinx farmworker and non-farmworker families (n = 73 and 65, respectively). Measures were created of months exposure through living adjacent to farm fields and having household members who worked in jobs exposing them to toxic chemicals. Data were divided into time periods of in utero, early childhood (birth-35 months) and later childhood (36–96 months). Cluster analysis compared the measures for children from farmworker and non-farmworker parents. (3) Results: Although, as a group, children from farmworker families have greater lifetime months of probable exposure to pesticides than children in non-farmworker families, cluster analysis reveals groups of children who do not follow that pattern. (4) Conclusions: The life history calendar is a technique for obtaining data on early life toxic chemical exposure that may help assign children to proper exposure groups. Conducting secondary analyses using such information can help to clarify the association of exposures to health outcomes.

scholarly journals Using family atopy scores to identify the risk of atopic dermatitis in infants

2014 ◽  
Vol 54 (6) ◽  
pp. 330
Author(s):  
Melisa Anggraeni ◽  
Ketut Dewi Kumara Wati ◽  
Ketut Tangking
Keyword(s):  
Atopic Dermatitis ◽  
Cohort Study ◽  
Pregnant Woman ◽  
Environmental Factors ◽  
Antenatal Care ◽  
Early Life ◽  
Early Interventions ◽  
Chi Square

Background Atopic dermatitis is the first manifestation ofallergic disease in early life. Early interventions may prevent thedevelopment of allergy disease. Allergy trace cards have beenused to identify the level of allergic risk, based on family atopyscores. Because environmental factors may also influence thedevelopment of atopic dermatitis, the usefulness of the allergytrace card needs to be reevaluated.Objective To compare the incidence of atopic dermatitis ininfants aged 0-4 months with total family atopy scores of > 0 tothose with scores of 0.Methods We conducted this cohort study from June 1, 2012 toDecember 31, 2012 at Sanglah Hospital, Denpasar. Family atopyscore was tabulated from all pregnant woman in the ObstetricOutpatient Clinic and the Maternity Room. Subjects were dividedinto two groups based on their total family atopy score: those withscores > 0 and those with scores of 0. The appearance of atopicdermatitis symptoms in the infants were evaluated until theyreached 4 months of age. The incidence of atopic dermatitis intwo groups was compared using Chi-square test.Results The incidence of atopic dermatitis in this study was 10.9%.The group with total family atopy scores of 0 had a significantlyhigher incidence of atopic dermatitis than the group with scores> 0 (adjusted RR 22.5; 95%CI 8.8 to 57.0; P = 0.001).Conclusion The incidence of atopic dermatitis is higher ininfants with total family atopy score > 0 and this group has a 22.5times higher risk of atopic dermatitis compared to infants withtotal family atopy score of 0. Allergy trace cards are relevant indifferentiating the risk of atopy with regards to development ofatopic dermatitis. We suggest that family atopy scores be evaluatedduring antenatal care in order to limit the development of atopicdermatitis in infants.

Development of atopic dermatitis according to age of onset and association with early-life exposures

2012 ◽  
Vol 130 (1) ◽  
pp. 130-136.e5 ◽  
Author(s):  
Caroline Roduit ◽  
Remo Frei ◽  
Georg Loss ◽  
Gisela Büchele ◽  
Juliane Weber ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Early Life ◽  
Age Of Onset ◽  
Early Life Exposures

scholarly journals Events in Normal Skin Promote Early-Life Atopic Dermatitis—The MPAACH Cohort

2020 ◽  
Vol 8 (7) ◽  
pp. 2285-2293.e6 ◽  
Author(s):  
Jocelyn M. Biagini Myers ◽  
Michael G. Sherenian ◽  
Asel Baatyrbek Kyzy ◽  
Rosario Alarcon ◽  
Amen An ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Early Life ◽  
Normal Skin

scholarly journals Early life atopic dermatitis increases food allergy risk throughout childhood

2019 ◽  
Vol 143 (2) ◽  
pp. AB125
Author(s):  
Anne Marie Singh ◽  
Christopher J. Tisler ◽  
Lisa Salazar ◽  
Susan Doyle ◽  
Michael D. Evans ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Early Life

Gut microbiome skin axis in the development of atopic dermatitis

2021 ◽  
pp. 1-6
Author(s):  
Hitham Abduarhman Alghamdi ◽  
Ahmed Behieldin ◽  
Sherif Edris
Keyword(s):  
Staphylococcus Aureus ◽  
Atopic Dermatitis ◽  
Gut Microbiome ◽  
Early Life ◽  
Skin Diseases ◽  
Skin Microbiome ◽  
Healthy Skin ◽  
Immunological Activity ◽  
Bacterial Composition ◽  
Strong Relation

Abstract Atopic dermatitis (AD) is the main focus of this review which mostly starts with children in early life. Beside the etiological factors like environmental, dietary or medical exposures, Gut-skin axis microbiome studies have an impact to investigate and to understand the relation between the gut microbiome and changes to the skin microbiom and some skin diseases resulting like AD. Infants start forming their microbiome in early life and some researches suggest that this time have a crucial role in development of AD. Balanced bacterial composition is important to maintain healthy skin as the gut microbiome dysbiosis may result in dramatic shifting in the skin microbiome that gives better chance for some bacteria such as Staphylococcus aureus to over prevail which has been reported to contribute in AD development. Among several factors, immunological activity has a strong relation to microbiome changed composition and development of AD. Continuous....  

scholarly journals P2-319 Cord blood vitamin D levels are associated with early life atopic dermatitis

2011 ◽  
Vol 65 (Suppl 1) ◽  
pp. A310-A311
Author(s):  
G. Wegienka ◽  
S. Havstad ◽  
D. Ownby ◽  
E. Zoratti ◽  
C. C. Johnson
Keyword(s):  
Vitamin D ◽  
Atopic Dermatitis ◽  
Cord Blood ◽  
Early Life ◽  
Vitamin D Levels
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