Risk factors, clinical course and long‐term prognosis in hidradenitis suppurativa: a cross‐sectional study

2014 ◽  
Vol 171 (4) ◽  
pp. 819-824 ◽  
Author(s):  
C.B. Kromann ◽  
I.E. Deckers ◽  
S. Esmann ◽  
J. Boer ◽  
E.P. Prens ◽  
...  
Dermatology ◽  
2019 ◽  
Vol 236 (1) ◽  
pp. 37-45 ◽  
Author(s):  
Carlos Cuenca-Barrales ◽  
Alejandro Molina-Leyva

Background: Hidradenitis suppurativa (HS) has a high impact on quality of life. However, sexual health has scarcely been investigated. Objective: To describe the frequency of sexual dysfunction (SD) in women and erectile dysfunction (ED) in men with HS and to explore potential risk factors. Patients and Methods:We conducted a cross-sectional study using a crowd-sourced online questionnaire spread by the Spanish hidradenitis suppurativa patients’ association (ASENDHI). Results: In total, 393 participants answered the questionnaire. SD was found in 51% (95% CI 45–57%) of women and ED in 60% (95% CI 49–70%) of men. Factors related to SD were education status, patient’s global assessment for disease activity, numeric rating scale for pain and unpleasant odour and the absence of a stable relationship. Factors related to ED were increasing age, the presence of active lesions in the genital area and the number of areas affected by active lesions. Conclusions: There is a high prevalence of SD and ED in HS patients. Being in a stable relationship has been a protective factor of SD in women. The results suggest that sexual impairment in HS patients is due, at least in part, to disease activity, symptoms and active lesions.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A788-A789
Author(s):  
Leonardo A M Alvares ◽  
Lívia M Santos ◽  
Henrique A Ramos ◽  
Larissa G Rodeghel ◽  
Nathan B Cavenaghi ◽  
...  

Abstract Introduction: Few data of long-term outcomes of cardiovascular (CVRF) risk factors of transgender women (TW) undergoing gender-affirming hormone therapy (GAHT) are available. Objectives: Evaluate CV risk factors after long-term GAHT in TW. Methods: A cross-sectional study was carried out with 8 TW (average age of 34.0 ±4.8 yo), 8 matched CM and 8 CW on age, body mass index (BMI) and activity level. All TW were non-gonadectomized subjects and were in estrogen [(E); transdermal estradiol (n=2), oral estradiol (n=3) and conjugated estrogen (n=3)] plus cyproterone acetate (CA) (n=8) therapy in an average time of 15.6 ±8.7 years. Results: Total Testosterone (ng/dL) level of TW, CW and CM were 83,5 (range 12,0-637,0), 20,5 (range 12,0-41,0) and 480,5 (range 264,0-843,0), respectively. It was similar between TW and CW (p=0,7284) and different in the comparison TWvsCM (p=0,0325). In TW group, the median of blood glucose was 84 mg / dL, HBA1c 5.1%, total cholesterol 146 mg / dL, HDLc 43 mg / dL, LDLc 89 mg / dL and triglycerides 81.5 mg / dL. In the comparison with other groups, there was no difference from the statistical point of view. It is necessary to emphasize the HDLc of TW (43 mg/dL) which was exactly the same of CM (p>0,999) and lower than CW (60 mg/dL)(p=0,0720). Systolic Blood Pressure (SBP)(mmHg) of TW (126±13) was higher than that of CW (95±11;p<0.001) and equal to that of CM (115±9;p=0.1489). Regards Diastolic Blood Pressure (DBP) (mmHg), the medians of TW, CW and CM were 80, 60 and 80, respectively, and in the comparison TWxCW p = 0.0070 and TWxCM p> 0.9999. Discussion: Youth TW (16.3 ± 1.4 yo) taking an average estradiol dose of 1.5 ± 1.0 mg/day, with an average AGHT duration of 12.3 ± 9.9 months matched to controls on age and BMI did have higher HDL than CW and TW participants were more insulin resistant than CM. About SBP of that youth TW (107 ± 12), it was lower than CW 113 ± 7 (p>0,05) and CM 116 ± 8 (p<0,001). Other previous study showed that after 6 months of estradiol use, in doses ranging from 2 to 8 mg daily glucose enhanced 6 mg/dL (from 86 to 92) as well as TC from 170 to 178 mg/dL, HDLc from 50 to 54 mg/dL, TGL from 102 to 115 mg/dL, and LDL did not change (93), while a systematic review and meta-analysis showed increased only in TG levels. SBP and DBP increased on average of 7,2 mmHg and 5,7 mmHg, respectively. Conclusion: Metabolic findings observed after the first few months of TW GAHT appear to remain at long term, except for HDLc. SBP and DBP appear to increase in the long term, after a drop initially observed.


2020 ◽  
Vol 7 (2) ◽  
pp. 92-100
Author(s):  
Ni Luh Sri Wahyuni ◽  
Tina Handayani Nasution ◽  
Edy Widjajanto

The prevalence of Acute Coronary Syndrome (ACS) is increasing in both developed and developing countries. Uncontrolled risk factors such as smoking, hypertension, and fewer activities are the main causes of ACS recurrence within 30 days after the acute presentation. This study aims to analyze risk factors related to the recurrence rate of ACS patients in Pakraman and non-Pakraman villages in Buleleng Regency, Bali Province. Observational analytics with Cross-Sectional Study are used in this study involving 130 patients within 1 month. Data is collected through two (2) stages using a questionnaire. The bivariate analysis shows that both smoking groups (p = 0.003 and p = 0.008) and hypertension groups (p = 0.02 and p = 0.01) are associated with ACS recurrence, while physical activity groups are not related (p = 0.455 and p = 0.565). Logistic regression results show that smoking (5.633) is highly associated with ACS recurrence in Pakraman villages, while hypertension (4.784) is highly associated with ACS recurrence in non-Pakraman villages. ACS handling is important in the acute period and in the long-term to prevent the risk of recurrence.


2021 ◽  
Author(s):  
Xuening Chang ◽  
Yifan Yang ◽  
Li Ruizhen

Abstract Objective. To understand the prevalence of domestic violence (DV) in Wuhan, China, to explore the correlation between domestic violence and husbands. Methods. A cross-sectional study was conducted in a community health center in Wuhan from June 2015 to December 2015. Participants were 1015 women who came to the center for gynecological examination. They were assessed using WHO violence against women instrument to evaluate the prevalence of domestic violence. Chi-square test, Wilcoxon rank test and unadjusted and adjusted logistic regression analysis were used to analyze the possible risk factors of domestic violence. Results. The prevalence of domestic violence was 29.36% (298/1015). The risk factors included heavy physical labor (OR=3.56, 95%CI:1.63~7.78), long-term drinking (OR=1.61, 95%CI:1.20~2.16), overweight or obesity (OR=1.38, 95%CI:1.02~1.88) and long-term smoking (OR=1.02, 95%CI:1.01~1.04). Protective factors were higher education (OR=0.78, 95%CI: 0.66-0.93). Conclusion. The prevalence of domestic violence in women from Wuhan, China was common. We might decrease the occurrence of the possible risk factors of domestic violence to control it.


2012 ◽  
Vol 2 (2) ◽  
pp. 104-117
Author(s):  
Wasif Gillani ◽  
Syed Sulaiman ◽  
Shameni Sundram ◽  
Maisharah Sheikh Ghadzi ◽  
Noor Haroon ◽  
...  

Introduction: The prevalence of diabetes is on the increase and an estimated 239 million people worldwide are expected to have the condition by the year 2020 (1). Diabetes mellitus (DM) represents a serious healthcare challenge. The aim of the study was to evaluate the patient clinical characteristics and risk factors for long term complications in the endocrine clinic of Hospital Penang, Malaysia.Methods: Descriptive Prospective cross-sectional study design was chosen. To achieve a power of 0.7 with alpha set at 0.05, 186 subjects were required for the study but researcher increase the sample to 297 in caseof drop out. Self-developed data collection form was used to collect the patient information.Results: 297 (100%) patients were enrolled from OPD diabetic clinic of Hospital Palau Pinang. Among the sample 150 (50.5%) were males and rest 147 (49.5%) females. Malay males mean weight at the time of diagnosis significantly higher (p<0.001,) as compared to other ethnics, same results found among Malay females (p<0.001). Findings suggested increased number of risk factors among the study population. Finding alsoshowed that hypertension found among all the classes of diagnosis. Signifi cant variable are diagnosis class and medication consideration.Conclusion of the study suggested that majority of patients are at high risk of long-term complications and comorbidies. It has been found that increased rate of risk factors have been found among the study population and non-significant to sociodemographic differences.


2019 ◽  
Vol 47 (02) ◽  
pp. 132-132
Author(s):  
Sebastian Ganz

Nathues C, Janssen E, Duengelhoef A et al. Cross-sectional study on risk factors for Porcine Reproductive and Respiratory Syndrome virus sow herd instability in German breeding herds. Acta Vet Scand 2018; 60 (1): 1–8 In mit PRRSV (Porcine Reproductive and Respiratory Syndrom Virus) infizierten Schweinebeständen zeigen die Tiere oftmals ernsthafte klinische Symptome. Die Schwere der Symptomatik hängt von der Virulenz der jeweiligen Virusstämme ab. Deshalb ist die Impfung gegen diesen Erreger sinnvoll und wird empfohlen, auch wenn sie nicht immer klinische Fälle verhindert bzw. das Virus vollends eliminiert. Aufgrund dessen rückt die Prävention durch Verbesserung der innerbetrieblichen Abläufe zunehmend in den Fokus. Um solche Maßnahmen erfolgreich etablieren zu können, ist es wichtig, den epidemiologischen Status der Herde und mögliche Risikofaktoren zu kennen. Ziel der Studie war deshalb, die Prävalenz der Infektion in Sauenbetrieben in Norddeutschland zu eruieren und verschiedene Arbeitsabläufe hinsichtlich des Risikos der Erregerverbreitung zu untersuchen.


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