A Comparison of Physiologically Based Pharmacokinetic Model Predictions and Experimental Data for Inhaled Ethanol in Male and Female B6C3F1Mice, F344 Rats, and Humans

Gina M. Pastino; Bahman Asgharian; Kay Roberts; Michele A. Medinsky; James A. Bond

doi:10.1006/taap.1997.8161

A Comparison of Physiologically Based Pharmacokinetic Model Predictions and Experimental Data for Inhaled Ethanol in Male and Female B6C3F1Mice, F344 Rats, and Humans

Toxicology and Applied Pharmacology ◽

10.1006/taap.1997.8161 ◽

1997 ◽

Vol 145 (1) ◽

pp. 147-157 ◽

Cited By ~ 40

Author(s):

Gina M. Pastino ◽

Bahman Asgharian ◽

Kay Roberts ◽

Michele A. Medinsky ◽

James A. Bond

Keyword(s):

Experimental Data ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Male And Female ◽

Physiologically Based Pharmacokinetic ◽

Model Predictions ◽

Physiologically Based ◽

F344 Rats

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Physiologically‐based pharmacokinetic model predictions of inter‐ethnic differences in imatinib pharmacokinetics and dosing regimens

British Journal of Clinical Pharmacology ◽

10.1111/bcp.15084 ◽

2021 ◽

Author(s):

Jeffry Adiwidjaja ◽

Annette S. Gross ◽

Alan V. Boddy ◽

Andrew J. McLachlan

Keyword(s):

Ethnic Differences ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Model Predictions ◽

Physiologically Based ◽

Dosing Regimens

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Physiologically Based Pharmacokinetic Model Predictions of Panobinostat (LBH589) as a Victim and Perpetrator of Drug-Drug Interactions

Drug Metabolism and Disposition ◽

10.1124/dmd.117.076851 ◽

2017 ◽

Vol 45 (12) ◽

pp. 1304-1316 ◽

Cited By ~ 13

Author(s):

Heidi J. Einolf ◽

Wen Lin ◽

Christina S. Won ◽

Lai Wang ◽

Helen Gu ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Model Predictions ◽

Physiologically Based

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DEVELOPMENT OF A PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL FOR METHYL ETHYL KETONE IN F344 RATS

Journal of Toxicology and Environmental Health Part A ◽

10.1080/00984100290071207 ◽

2002 ◽

Vol 65 (13) ◽

pp. 881-896 ◽

Cited By ~ 8

Author(s):

Karla D. Thrall ◽

Jolen J. Soelberg ◽

Karl K. Weitz ◽

Angela D. Woodstock

Keyword(s):

Methyl Ethyl Ketone ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Methyl Ethyl ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

F344 Rats

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Physiologically based pharmacokinetic model predictions of ivosidenib (AG-120) as a victim and perpetrator of drug–drug interactions

Drug Metabolism and Pharmacokinetics ◽

10.1016/j.dmpk.2018.09.238 ◽

2019 ◽

Vol 34 (1) ◽

pp. S70

Author(s):

Chandra Prakash ◽

Yue Chen ◽

Bin Fan ◽

David Dai ◽

Kha Le ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Model Predictions ◽

Physiologically Based

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Physiologically based pharmacokinetic model development for trazodone: application to paediatric dose projection

10.26226/morressier.5971be87d462b80290b534f2 ◽

2017 ◽

Author(s):

F. Calisti

Keyword(s):

Pharmacokinetic Model ◽

Model Development ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Paediatric Dose

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Risk Assessment of Perfluorooctane Sulfonate (PFOS) using Dynamic Age Dependent Physiologically based Pharmacokinetic Model (PBPK) across human lifetime

Environmental Research ◽

10.1016/j.envres.2021.111287 ◽

2021 ◽

pp. 111287

Author(s):

Deepika Deepika ◽

Raju Prasad Sharma ◽

Marta Schuhmacher ◽

Vikas Kumar

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Perfluorooctane Sulfonate ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Age Dependent

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Human risk assessment of di-isobutyl phthalate through the application of a developed physiologically based pharmacokinetic model of di-isobutyl phthalate and its major metabolite mono-isobutyl phthalate

Archives of Toxicology ◽

10.1007/s00204-021-03057-5 ◽

2021 ◽

Author(s):

Seung-Hyun Jeong ◽

Ji-Hun Jang ◽

Hea-Young Cho ◽

Yong-Bok Lee

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Major Metabolite ◽

Physiologically Based Pharmacokinetic Model ◽

Human Risk Assessment ◽

Human Risk ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically‐Based Pharmacokinetic Model for Alectinib, Ruxolitinib, and Panobinostat in The Presence of Cancer, Renal Impairment, and Hepatic Impairment

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2282 ◽

2021 ◽

Author(s):

Mo'tasem M. Alsmadi

Keyword(s):

Renal Impairment ◽

Hepatic Impairment ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Development of a Physiologically-Based Pharmacokinetic Model for Perchloroethylene Using Tissue Concentration-Time Data

Toxicology and Applied Pharmacology ◽

10.1006/taap.1994.1179 ◽

1994 ◽

Vol 128 (1) ◽

pp. 50-59 ◽

Cited By ~ 15

Author(s):

C.E. Dallas ◽

X.M. Chen ◽

K. Obarr ◽

S. Muralidhara ◽

P. Varkonyi ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Tissue Concentration ◽

Physiologically Based Pharmacokinetic Model ◽

Time Data ◽

Physiologically Based Pharmacokinetic ◽

Concentration Time ◽

Physiologically Based

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Development of a Physiologically Based Pharmacokinetic Model for Estradiol in Rats and Humans: A Biologically Motivated Quantitative Framework for Evaluating Responses to Estradiol and Other Endocrine-Active Compounds

Toxicological Sciences ◽

10.1093/toxsci/69.1.60 ◽

2002 ◽

Vol 69 (1) ◽

pp. 60-78 ◽

Cited By ~ 37

Author(s):

D. R. Plowchalk

Keyword(s):

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Active Compounds ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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