scholarly journals Urinary coproporphyrin I/(I + III) ratio as a surrogate for MRP2 or other transporter activities involved in methotrexate clearance

2014 ◽  
Vol 78 (2) ◽  
pp. 329-342 ◽  
Author(s):  
Isabelle Benz-de Bretagne ◽  
Noël Zahr ◽  
Amélie Le Gouge ◽  
Jean-Sébastien Hulot ◽  
Caroline Houillier ◽  
...  
Keyword(s):  
Urinary Coproporphyrin ◽  
Coproporphyrin I

Developmental characteristics of urinary coproporphyrin I/(I + III) ratio

2016 ◽  
Vol 58 (10) ◽  
pp. 974-978 ◽  
Author(s):  
Jun Kunikata ◽  
Hitoshi Okada ◽  
Susumu Itoh ◽  
Takashi Kusaka
Keyword(s):  
Developmental Characteristics ◽  
Urinary Coproporphyrin ◽  
Coproporphyrin I

Liquid-chromatographic separation and determination of coproporphyrins I and III in urine.

1983 ◽  
Vol 29 (2) ◽  
pp. 350-353 ◽  
Author(s):  
T Sakai ◽  
Y Niinuma ◽  
S Yanagihara ◽  
K Ushio
Keyword(s):  
Acetic Acid ◽  
Present Method ◽  
High Performance ◽  
Normal Subjects ◽  
Liquid Chromatographic Separation ◽  
Acetic Acid Treatment ◽  
Liquid Chromatographic ◽  
Urinary Coproporphyrin ◽  
Coproporphyrin I

Abstract We describe a method of determining coproporphyrin I, III, and I plus III in urine by "high-performance" liquid chromatography. Urine is simply injected after dilution with an equal volume of glacial acetic acid. Some urinary coproporphyrin apparently binds zinc without acetic acid treatment. The working linear range of coproporphyrin concentrations is 10 to 2000 micrograms/L of urine. The sensitivity of the method is sufficient to detect as little as 10 micrograms of coproporphyrins per liter of urine. Analytical recoveries for both coproporphyrins were 96.7-106%. Results by the present method and those by an extraction method (Br J Ind Med 31:72-74, 1974) correlate well (r = 0.975). Mean (and range) coproporphyrin I, III, and I plus III concentrations in urine from normal subjects are 33.7 (7-75), 28.6 (0-130), and 62.2 (7-174) micrograms/L, respectively.

scholarly journals A MICROMETHOD FOR THE QUANTITATIVE DETERMINATION OF THE URINARY COPROPORPHYRIN ISOMERS (I AND III)

1947 ◽  
Vol 168 (1) ◽  
pp. 133-144
Author(s):  
Samuel Schwartz ◽  
Violet Hawkinson ◽  
Sanford Cohen ◽  
Cecil James Watson
Keyword(s):  
Quantitative Determination ◽  
Coproporphyrin Isomers ◽  
Urinary Coproporphyrin

scholarly journals Relationship of Hemoglobin Level and Plasma Coproporphyrin‐I Concentrations as an Endogenous Probe for Phenotyping OATP1B

2021 ◽  
Author(s):  
Yosuke Suzuki ◽  
Yuri Sasamoto ◽  
Teruhide Koyama ◽  
Chisato Yoshijima ◽  
Ayako Oda ◽  
...  
Keyword(s):  
Hemoglobin Level ◽  
Relationship Of ◽  
Coproporphyrin I

Increased urinary coproporphyrin excretion observed in patients with differently staged Hodgkin's disease treated with chemotherapy

2005 ◽  
Vol 51 (3) ◽  
pp. 283-288 ◽  
Author(s):  
Arnaldo Pinelli ◽  
Cirillo Mussini ◽  
Marina Buratti ◽  
Maria Parmiggiani-Venezia ◽  
Silvio Trivulzio
Keyword(s):  
Hodgkin's Disease ◽  
Hodgkin’S Disease ◽  
Urinary Coproporphyrin

CHRONIC LEAD ENCEPHALOPATHY

PEDIATRICS ◽  
1960 ◽  
Vol 25 (2) ◽  
pp. 309-315
Author(s):  
Harry H. White ◽  
Fred D. Fowler
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Pediatric Patients ◽  
Early Recognition ◽  
Central Nervous System Involvement ◽  
Fast Screening ◽  
The Central Nervous System ◽  
Lead Encephalopathy ◽  
Urinary Coproporphyrin

Chronic lead encephalopathy must be considered in the differential diagnosis of pediatric patients who present with manifestations of schizophrenia, behavior disorders or degenerative diseases of the central nervous system. Determination of urinary coproporphyrin is a simple, fast screening procedure applicable to office practice. The prognosis for normal mental development following encephalopathy is poor. It is hoped that early recognition of the more subtle signs of central nervous system involvement will allow treatment to be instituted soon enough to prevent the crippling mental deterioration which is so often a sequela of lead poisoning.

scholarly journals Comprehensive Evaluation of the Utility of 20 Endogenous Molecules as Biomarkers of OATP1B Inhibition Compared with Rosuvastatin and Coproporphyrin I

2018 ◽  
Vol 368 (1) ◽  
pp. 125-135 ◽  
Author(s):  
Shelby Barnett ◽  
Kayode Ogungbenro ◽  
Karelle Ménochet ◽  
Hong Shen ◽  
W. Griffith Humphreys ◽  
...  
Keyword(s):  
Comprehensive Evaluation ◽  
Coproporphyrin I
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