Systematic review with meta-analysis: early infant feeding and coeliac disease - update 2015

2015 ◽  
Vol 41 (11) ◽  
pp. 1038-1054 ◽  
Author(s):  
H. Szajewska ◽  
R. Shamir ◽  
A. Chmielewska ◽  
M. Pieścik-Lech ◽  
R. Auricchio ◽  
...  
2012 ◽  
Vol 36 (7) ◽  
pp. 607-618 ◽  
Author(s):  
H. Szajewska ◽  
A. Chmielewska ◽  
M. Pieścik-Lech ◽  
A. Ivarsson ◽  
S. Kolacek ◽  
...  

Author(s):  
Stephen E. Roberts ◽  
Sian Morrison‐Rees ◽  
Nikhil Thapar ◽  
Marc A. Benninga ◽  
Osvaldo Borrelli ◽  
...  

Nutrients ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 142 ◽  
Author(s):  
Emma Clappison ◽  
Marios Hadjivassiliou ◽  
Panagiotis Zis

Background: Coeliac disease (CD) is increasingly prevalent and is associated with both gastrointestinal (GI) and extra-intestinal manifestations. Psychiatric disorders are amongst extra-intestinal manifestations proposed. The relationship between CD and such psychiatric disorders is not well recognised or understood. Aim: The aim of this systematic review and meta-analysis was to provide a greater understanding of the existing evidence and theories surrounding psychiatric manifestations of CD. Methodology: An online literature search using PubMed was conducted, the prevalence data for both CD and psychiatric disorders was extracted from eligible articles. Meta analyses on odds ratios were also performed. Results: A total of 37 articles were included in this review. A significant increase in risk was detected for autistic spectrum disorder (OR 1.53, 95% CI 1.24–1.88, p < 0.0001), attention deficit hyperactivity disorder (OR 1.39, 95% CI 1.18–1.63, p < 0.0001), depression (OR 2.17, 95% CI 2.17–11.15, p < 0.0001), anxiety (OR 6.03, 95% CI 2.22–16.35, p < 0.0001), and eating disorders (OR 1.62, 95% CI 1.37–1.91, p < 0.00001) amongst the CD population compared to healthy controls. No significant differences were found for bipolar disorder (OR 2.35, 95% CI 2.29–19.21, p = 0.43) or schizophrenia (OR 0.46, 95% CI 0.02–10.18, p = 0.62). Conclusion: CD is associated with an increased risk of depression, anxiety, eating disorders as well as ASD and ADHD. More research is required to investigate specific biological explanations as well as any effect of gluten free diet.


2010 ◽  
Vol 52 (8) ◽  
pp. 700-707 ◽  
Author(s):  
ELENA LIONETTI ◽  
RUGGIERO FRANCAVILLA ◽  
PIERO PAVONE ◽  
LORENZO PAVONE ◽  
TERESA FRANCAVILLA ◽  
...  

Gut ◽  
2011 ◽  
Vol 60 (Suppl 1) ◽  
pp. A18-A18
Author(s):  
A. Sainsbury ◽  
D. S. Sanders ◽  
A. C. Ford

Nutrients ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1950 ◽  
Author(s):  
Mercedes Castaño ◽  
Rubén Gómez-Gordo ◽  
David Cuevas ◽  
Concepción Núñez

We aimed to estimate the seroprevalence and the prevalence of coeliac disease (CD) in women with reproductive problems. A systematic review of English published articles until June 2019 was performed in PubMed and Scopus using the terms: (infertility and (coeliac disease OR gluten) OR (miscarriage and (coeliac disease OR gluten) OR (abortion and (coeliac disease OR gluten). All articles showing numerical data of anti-transglutaminase type 2 or anti-endomisium antibodies, or intestinal biopsy information were included. The study group comprised women with overall infertility, unexplained infertility, or recurrent spontaneous abortions. Two authors independently performed data extraction using a predefined data sheet. The initial search yielded 310 articles, and 23 were selected for data extraction. After meta-analysis, the pooled seroprevalence was very similar for overall and unexplained infertility, with a pooled proportion of around 1.3%–1.6%. This implies three times higher odds of having CD in infertility when compared to controls. The pooled prevalence could not be accurately calculated due to the small sample sizes. Further studies with increased sample sizes are necessary before giving specific recommendations for CD screening in women with reproductive problems, but current data seem to support a higher risk of CD in these women.


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