scholarly journals Early childhood infections and the use of antibiotics and antipyretic‐analgesics in Finland, Estonia and Russian Karelia

2019 ◽  
Vol 108 (11) ◽  
pp. 2075-2082 ◽  
Author(s):  
Neea Mustonen ◽  
Heli Siljander ◽  
Aleksandr Peet ◽  
Vallo Tillmann ◽  
Taina Härkönen ◽  
...  
Keyword(s):  
Early Childhood ◽  
Childhood Infections ◽  
Russian Karelia

scholarly journals Early Childhood Infections and the Risk of Islet Autoimmunity: The Diabetes Autoimmunity Study in the Young (DAISY)

Diabetes Care ◽  
2012 ◽  
Vol 35 (12) ◽  
pp. 2553-2558 ◽  
Author(s):  
J. K. Snell-Bergeon ◽  
J. Smith ◽  
F. Dong ◽  
A. E. Baron ◽  
K. Barriga ◽  
...  
Keyword(s):  
Early Childhood ◽  
Islet Autoimmunity ◽  
Childhood Infections

scholarly journals Nonspecific effect of BCG vaccination at birth on early childhood infections: a randomized, clinical multicenter trial

2016 ◽  
Vol 80 (5) ◽  
pp. 681-685 ◽  
Author(s):  
Jesper Kjærgaard ◽  
Nina M. Birk ◽  
Thomas N. Nissen ◽  
Lisbeth M. Thøstesen ◽  
Gitte T. Pihl ◽  
...  
Keyword(s):  
Early Childhood ◽  
Multicenter Trial ◽  
Bcg Vaccination ◽  
Nonspecific Effect ◽  
Childhood Infections

scholarly journals Early childhood infections and body mass index in adolescence

2021 ◽  
Author(s):  
Annemarijn C. Prins-van Ginkel ◽  
Alet H. Wijga ◽  
Patricia C. J. Bruijning-Verhagen ◽  
Bert Brunekreef ◽  
Ulrike Gehring ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Early Childhood ◽  
Body Mass ◽  
Childhood Infections

scholarly journals Early childhood infections, antistreptococcal and basal ganglia antibodies in adult ADHD: A preliminary study

2020 ◽  
Author(s):  
Francesco Oliva ◽  
Giulia di Girolamo ◽  
Francesca Malandrone ◽  
Noemi Iaia ◽  
Fiorella Biasi ◽  
...  
Keyword(s):  
Early Childhood ◽  
Basal Ganglia ◽  
Adult Adhd ◽  
Enzyme Linked Immunosorbent Assay ◽  
Continuous Variables ◽  
Recurrent Infections ◽  
Childhood Infections ◽  
Streptolysin O ◽  
Increased Risk ◽  
History Of

Abstract Background: To explore the relationship between adult Attention Deficit/ Hyperactivity Disorder (ADHD), antistreptococcal titers, ABGA, and recurrent infections during early childhood.Method: Childhood history of recurrent infections and a blood sample were collected in a sample of DSM-IV adult outpatients with ADHD. The anti-streptolysin O (ASO), anti-deoxyribonuclease B (anti-DNase B), and anti-basal ganglia antibodies (ABGA) titers were determined in patient plasma by enzyme-linked immunosorbent assay (ELISA). Titers positivity was evaluated following manufacturer's specifications. Absolute titers were also collected as continuous variables.Results: Fourteen out of 22 (63.6%) have had recurrent infections in childhood (i.e., seven, 31.8%, have had tonsillitis or adenoiditis and seven, 31.8%, have had any other infections). Eighteen patients (81.9%) were positive for anti-DNase B, five (22.7%) for ASO, and 4 (18.2%) were positive for both of them. Five participants (22.7%) were ABGA positive, whereas only two (9.1%) were positive for all three antibodies.Conclusions: Patients with ADHD might be more prone to infections during childhood and subclinical streptococcal infections during adulthood, moreover they seem to have an increased risk for basal ganglia autoimmunity in adulthood. Both infections and ensuing acquired autoimmunity could influence the neurodevelopmental process, by contributing, at least in part, to the ADHD pathogenesis.

Early childhood infections precede development of beta-cell autoimmunity and type 1 diabetes in children with HLA-conferred disease risk

2017 ◽  
Vol 19 (2) ◽  
pp. 293-299 ◽  
Author(s):  
N Mustonen ◽  
H Siljander ◽  
A Peet ◽  
V Tillmann ◽  
T Härkönen ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Early Childhood ◽  
Beta Cell ◽  
Disease Risk ◽  
Childhood Infections ◽  
Beta Cell Autoimmunity

Early childhood infections and risk of schizophrenia

2012 ◽  
Vol 200 (2-3) ◽  
pp. 214-217 ◽  
Author(s):  
Wenbin Liang ◽  
Tanya Chikritzhs
Keyword(s):  
Early Childhood ◽  
Childhood Infections

scholarly journals Early childhood infections, antistreptococcal and basal ganglia antibodies in adult ADHD: a preliminary study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Francesco Oliva ◽  
Giulia di Girolamo ◽  
Francesca Malandrone ◽  
Noemi Iaia ◽  
Fiorella Biasi ◽  
...  
Keyword(s):  
Early Childhood ◽  
Basal Ganglia ◽  
Adult Adhd ◽  
Enzyme Linked Immunosorbent Assay ◽  
Continuous Variables ◽  
Recurrent Infections ◽  
Childhood Infections ◽  
Streptolysin O ◽  
Increased Risk ◽  
History Of

Abstract Background To explore the relationship between adult Attention Deficit/ Hyperactivity Disorder (ADHD), antistreptococcal titers, ABGA, and recurrent infections during early childhood. Method Childhood history of recurrent infections and a blood sample were collected in a sample of DSM-IV adult outpatients with ADHD. The anti-streptolysin O (ASO), anti-deoxyribonuclease B (anti-DNase B), and anti-basal ganglia antibodies (ABGA) titers were determined in patient plasma by enzyme-linked immunosorbent assay (ELISA). Titers positivity was evaluated following manufacturer’s specifications. Absolute titers were also collected as continuous variables. Results Fourteen out of 22 (63.6%) have had recurrent infections in childhood (i.e., seven, 31.8%, have had tonsillitis or adenoiditis and seven, 31.8%, have had any other infections). Eighteen patients (81.9%) were positive for anti-DNase B, five (22.7%) for ASO, and 4 (18.2%) were positive for both of them. Five participants (22.7%) were ABGA positive, whereas only two (9.1%) were positive for all three antibodies. Conclusions patients with ADHD might be more prone to infections during childhood and subclinical streptococcal infections during adulthood. Moreover, they seem to have an increased risk for basal ganglia autoimmunity in adulthood. Both infections and the ensuing acquired autoimmunity could influence the neurodevelopmental process, by contributing, at least in part, to the ADHD pathogenesis.

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